KEGG   Streptococcus dysgalactiae subsp. equisimilis RE378: GGS_1891
Entry
GGS_1891          CDS       T02269                                 
Symbol
fhs2
Name
(GenBank) formate-tetrahydrofolate ligase
  KO
K01938  formate--tetrahydrofolate ligase [EC:6.3.4.3]
Organism
sda  Streptococcus dysgalactiae subsp. equisimilis RE378
Pathway
sda00670  One carbon pool by folate
sda01100  Metabolic pathways
sda01120  Microbial metabolism in diverse environments
sda01200  Carbon metabolism
sda01240  Biosynthesis of cofactors
Module
sda_M00140  C1-unit interconversion, prokaryotes
Brite
KEGG Orthology (KO) [BR:sda00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    GGS_1891 (fhs2)
Enzymes [BR:sda01000]
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.4  Other carbon-nitrogen ligases
    6.3.4.3  formate---tetrahydrofolate ligase
     GGS_1891 (fhs2)
SSDB
Motif
Pfam: FTHFS CbiA
Other DBs
NCBI-ProteinID: BAM62006
UniProt: A0A9W3ZR04
Position
2051181..2052854
AA seq 557 aa
MVLSDIEIANSVTMEPISKVANQLGIDEEALCLYGKYKAKIDARQLVALKDKPDGKLILV
TAISPTPAGEGKTTTSVGLVDALSAIGKKAVIALREPSLGPVFGVKGGAAGGGHAQVVPM
EDINLHFTGDFHAIGVANNLLAALIDNHIHHGNSLGIDSRRITWKRVVDMNDRQLRHIVD
GLQGKVNGVPREDGYDITVASEIMAILCLSENISDLKARLEKIIIGYNYQGEPVTAKDLK
AGGALAALLKDAIHPNLVQTLEHTPALIHGGPFANIAHGCNSVLATKLALKYADYAVTEA
GFGADLGAEKFIDIKCRMSGLRPAAVVLVATIRALKMHGGVPKADLATENVQAVVDGLPN
LDKHLANIQDVYGLPVVVAINKFPLDTDAELQAVYDACNKRGVDVVISDVWANGGAGGRE
LAEKVVTLAEQDNQFRFVYDEDDSIETKLTKIITKVYGGKGIRLTPTAKRELADLERLGF
GNYPICMAKTQYSFSDDAKKLGAPTDFTVTISNLKVSAGAGFIVALTGAIMTMPGLPKVP
ASETIDIDEEGNITGLF
NT seq 1674 nt   +upstreamnt  +downstreamnt
atggttttatcagatattgaaatagccaactctgtcactatggagcctatcagtaaggtt
gccaatcaattagggattgacgaggaagcgctctgtctctatggcaagtacaaggcaaaa
attgatgcccgtcaactggtcgccttaaaagacaaacctgatggcaaactcattcttgtc
actgctatctcaccaacaccagctggtgaaggcaaaaccactacttccgttggattggta
gatgctctttctgccattggaaaaaaagcagttattgcccttcgtgaaccttctcttggt
cctgtttttggggttaagggaggagctgctggcggtggccacgcgcaagttgtcccaatg
gaagacatcaaccttcactttacaggggactttcatgccatcggtgtcgccaacaactta
ttggctgccttgattgataaccacattcaccatggcaatagcctaggcattgattctaga
cgtatcacttggaaacgtgtggtggatatgaatgaccgccagcttcgtcatattgttgac
ggcttgcaaggcaaggtcaacggggttcctcgtgaagatggttatgacattaccgtcgcc
tctgaaatcatggcaatcctgtgcctatccgaaaatatttctgacctcaaagcccgcctt
gaaaaaatcatcatcggttacaactaccaaggtgaacctgtaacagctaaagacttgaaa
gctggtggtgccctagccgctctgctcaaggatgcgattcatcctaatctcgtgcaaacc
ttggaacacacaccagccctcattcacggcggcccatttgctaatatcgcccatggctgt
aatagtgtcctagccaccaaactagccttgaaatatgccgattatgccgttaccgaagct
ggatttggcgctgaccttggagctgaaaaattcattgacatcaaatgccgcatgtcaggc
cttcgcccagcagccgttgtcctagtagccactattcgtgcccttaaaatgcacggtggc
gttccaaaagcagacctggctactgaaaatgttcaggccgttgtggatggtttacctaac
cttgacaaacatttggctaatatccaagacgtctatggccttccagttgtcgtggcgatc
aataaattcccgcttgataccgatgctgaattacaagctgtctatgatgcctgcaacaaa
cgtggcgttgacgttgtgatttctgatgtttgggcaaatggcggagctggtggccgtgaa
ttagctgaaaaagtcgtgacactagccgagcaagacaatcaattccgctttgtttacgat
gaagatgatagcattgaaaccaaactgactaaaatcattaccaaggtttacggtggtaag
gggattagattgacccccacagccaaacgtgaactggctgacttagaacgcctcggcttt
ggcaactacccaatttgcatggccaaaacccaatattccttctcagacgatgccaaaaaa
cttggcgcaccaactgactttacagtgactattagcaacctcaaagtgtctgcaggagca
ggctttatcgttgctctgacgggtgctatcatgaccatgcctggccttccaaaagtacct
gccagcgaaacaattgatattgacgaggagggcaacatcacaggactattctaa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (7)   
   KEGG PATHWAY (5)   
   KEGG MODULE (2)   
Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (2)   
   Pfam (2)   
All databases (24)   

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