KEGG   Shigella dysenteriae Sd197: SDY_0457
Entry
SDY_0457          CDS       T00306                                 
Symbol
acrB
Name
(GenBank) acridine efflux pump
  KO
K18138  multidrug efflux pump
Organism
sdy  Shigella dysenteriae Sd197
Pathway
sdy01501  beta-Lactam resistance
sdy01503  Cationic antimicrobial peptide (CAMP) resistance
Brite
KEGG Orthology (KO) [BR:sdy00001]
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01501 beta-Lactam resistance
    SDY_0457 (acrB)
   01503 Cationic antimicrobial peptide (CAMP) resistance
    SDY_0457 (acrB)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:sdy02000]
    SDY_0457 (acrB)
   01504 Antimicrobial resistance genes [BR:sdy01504]
    SDY_0457 (acrB)
Transporters [BR:sdy02000]
 Other transporters
  Electrochemical potential-driven transporters [TC:2]
   SDY_0457 (acrB)
Antimicrobial resistance genes [BR:sdy01504]
 Gene sets
  Multipdrug resistance modules
   Multidrug resistance, efflux pump MexAB-OprM [MD:M00718]
    SDY_0457 (acrB)
SSDB
Motif
Pfam: ACR_tran SecD_SecF
Other DBs
NCBI-ProteinID: ABB60665
ShiBASE_China: SDY0457
UniProt: Q32J42
Position
448942..452091
AA seq 1049 aa
MPNFFIDRPIFAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVTISASYPGADAKTVQDT
VTQVIEQNMNGIDNLMYMSSNSDSTGTVQITLTFESGTDADIAQVQVQNKLQLAMPLLPQ
EVQQQGVSVEKSSSSFLMVVGVINTDGTMTQEDISDYVATNMKDAISRTSGVGDVQLFGS
QYAMRIWMNPNELNKFQLTPVDVITAIKAQNAQVAAGQLGGTPPVKGQQLNASIIAQTRL
TSTEEFGKILLKVNQDGSRVLLRDVAKIELGGENYDIIAEFNGQPASGLGIKLATGANAL
DTAAAIRAELAKMEPFFPSGLKIVYPYDTTPFVKISIHEVVKTLVEAIILVFLVIYLFLQ
NFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFGMVLAIGLLVDDAIVVVENVERVM
AEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMAL
SVLVALILTPALCATMLKPIAKGDHGEGKKGFFGWFNRMFEKSTHHYTDSVGGILRSTGR
YLVLYLIIVVGMAYLFVRLPSSFLPDEDQGVFMTMVQLPAGATQERTQKVLNEVTHYYLT
KEKNNVESVFAVNGFGFAGRGQNTGIAFVSLKDWADRPGEENKVEAITMRATRAFSQIKD
AMVFAFNLPAIVELGTATGFDFELIDQAGLGHEKLTQARNQLLAEAAKHSDMLTSVRPNG
LEDTPQFKIDIDQEKAQALGVSINDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYR
MLPDDIGNWYVRAADGQMVPFSAFSSSRWEYGSPRLERYNGLPSMEILGQAAPGKSTGEA
MELMEQLASKLPTGVGYDWTGMSYQERLSGNQAPSLYAISLIVVFLCLAALHESWSIPFS
VMLVVPLGVIGALLAATFRGLTNDVYFQVGLLTTIGLSAKNAILIVEFAKDLMDKEGKGL
IEATLDAVRMRLRPILMTSLAFILGVMPLVISTGAGSGAQNAVGTGVMGGMVTATVLAIF
FVPVFFVVVRHRFSRKNEDIEHSHTVDHH
NT seq 3150 nt   +upstreamnt  +downstreamnt
atgcctaatttctttatcgatcgcccgatttttgcgtgggtgatcgccattatcatcatg
ttggcaggggggctggcgatcctcaaactgccggtggcgcaatatcctacgattgcaccg
ccggcagtaacgatctccgcctcctacccaggcgctgatgcgaaaacagtgcaggacacg
gtgacacaggttatcgaacagaatatgaacggtatcgataacctgatgtacatgtcctct
aacagtgactccacgggtaccgtacagatcaccctgacctttgagtctggtactgatgcg
gatatcgcgcaggttcaggtgcagaacaaactgcagctggcgatgccgttgctgccgcaa
gaagttcagcagcaaggggtgagcgttgagaaatcatccagcagcttcctgatggttgtc
ggcgttatcaacaccgatggcaccatgacgcaggaggatatctccgactacgtggcgacg
aatatgaaagatgccattagccgtacgtcgggcgtgggtgacgttcagttgttcggttca
cagtacgcgatgcgtatctggatgaacccgaatgaactgaacaaattccagctaacaccg
gttgatgttattaccgccatcaaagcgcagaacgcccaggttgcggcgggtcagctcggt
ggtacgccgccggtgaaaggccaacagcttaacgcctctattattgctcagacgcgtctg
acctctactgaagagtttggcaaaatcctgctgaaagtgaatcaggatggttcccgcgtg
ctgctgcgtgatgtggcgaagattgagctgggtggtgagaactacgacatcatcgcagag
tttaacggccaaccggcttccggtctggggatcaagctggcgaccggtgcaaacgcgctg
gataccgctgcggcaatccgtgctgaactggcgaagatggaaccgttcttcccgtcgggt
ctgaaaattgtttacccgtacgacaccacgccgttcgtgaaaatctctattcacgaagtg
gttaaaacgctggtcgaagcgatcatcctcgtgttcctggttatatatctgttcctgcag
aacttccgcgcgacgttgattccgaccattgccgtaccggtggtattgctcgggaccttt
gccgtccttgccgcctttggcttctcgataaacacgctaacaatgttcgggatggtgctc
gccatcggcctgttggtggatgacgctatcgttgtggtagaaaacgttgagcgtgtgatg
gcggaagaaggtttgccgccaaaagaagccacccgtaagtcgatggggcagattcagggc
gctctggtcggtatcgcgatggtactgtcggcggtattcgtaccgatggccttctttggc
ggttctactggtgctatctatcgtcagttctctattaccattgtttcagcaatggcgctg
tcggtactggtggcgttgatcctgactccagctctttgtgccaccatgctgaaaccgatt
gccaaaggcgatcacggggaaggtaaaaaaggcttcttcggctggtttaaccgcatgttc
gagaagagcacgcaccactacaccgacagcgtaggcggtattctgcgcagtacggggcgt
tacctggtgctgtatctgatcatcgtggtcggcatggcctatctgttcgtgcgtctgcca
agctccttcttgccagatgaggaccagggcgtgtttatgaccatggttcagctgccagca
ggtgcaacgcaggaacgtacacagaaagtgctcaatgaggtaacgcattactatctgacc
aaagaaaagaacaacgttgagtcggtgttcgccgttaacggcttcggctttgcgggacgt
ggtcagaataccggtattgcgttcgtttccttgaaggactgggccgatcgtccgggtgaa
gaaaacaaagttgaagcgattaccatgcgtgcaacacgcgctttctcgcaaatcaaagat
gcgatggttttcgcctttaacctgcccgcaatcgtggaactgggtactgcaaccggcttt
gactttgagctgattgaccaggctggccttggtcacgaaaaactgactcaggcgcgtaac
cagctgcttgcagaagcagcgaagcactctgatatgttgaccagcgtacgtccaaacggt
ctggaagataccccgcagtttaagattgatatcgaccaggaaaaagcgcaggcgctgggt
gtttctatcaacgacatcaacaccactctgggcgctgcatggggcggtagctatgtgaac
gactttatcgaccgcggtcgtgtgaagaaagtttacgtcatgtcagaagcgaaataccgt
atgctgccggatgatatcggcaactggtatgttcgtgctgctgatggtcagatggtgcca
ttctcggcgttctcctcttctcgttgggagtacggttcgccgcgtctggaacgttacaac
ggcctgccatccatggaaatcttaggccaggcggcaccgggtaaaagtaccggtgaagca
atggagctgatggaacaactggcgagcaaactgcctaccggtgttggctatgactggacg
gggatgtcctatcaggaacgcctctccggcaaccaggcaccttcactgtacgcgatttcg
ttgattgtcgtgttcctgtgtctggcggcgctgcacgagagctggtcgattccgttctcc
gttatgctggtcgttccgctgggggttatcggtgcgttgctggctgccaccttccgtggc
ctgaccaatgacgtttacttccaggtaggcctgctcacaaccattgggttgtcggcgaag
aacgcgatacttatcgtcgaattcgccaaagacttgatggataaagaaggtaaaggtctg
attgaagcgacgcttgatgcggtgcggatgcgtttacgtccgatcctgatgacctcgctg
gcgtttattctcggcgttatgccgctggttatcagtactggtgctggttccggcgcgcag
aacgcagtaggtaccggtgtaatgggcgggatggtgaccgcaacggtactggcaatcttc
ttcgttccggtattctttgtggtggttcgccaccgctttagccgcaagaatgaagatatc
gagcacagccatactgtcgatcatcattga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (3)   
   KEGG PATHWAY (2)   
   KEGG MODULE (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
   SHIBASE_CHINA (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (2)   
   Pfam (2)   
All databases (14)   

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