KEGG   Spirochaeta africana: Spiaf_2344
Entry
Spiaf_2344        CDS       T01811                                 
Name
(GenBank) 3-isopropylmalate dehydratase, large subunit
  KO
K01703  3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35]
Organism
sfc  Spirochaeta africana
Pathway
sfc00290  Valine, leucine and isoleucine biosynthesis
sfc00660  C5-Branched dibasic acid metabolism
sfc01100  Metabolic pathways
sfc01110  Biosynthesis of secondary metabolites
sfc01210  2-Oxocarboxylic acid metabolism
sfc01230  Biosynthesis of amino acids
Module
sfc_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:sfc00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00660 C5-Branched dibasic acid metabolism
    Spiaf_2344
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    Spiaf_2344
Enzymes [BR:sfc01000]
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.33  3-isopropylmalate dehydratase
     Spiaf_2344
    4.2.1.35  (R)-2-methylmalate dehydratase
     Spiaf_2344
SSDB
Motif
Pfam: Aconitase
Other DBs
NCBI-ProteinID: AFG38376
UniProt: H9ULI3
Position
2649891..2651327
AA seq 478 aa
MAKRTLYNKVWDQHAVTRLPSGQTQLFIGLHMVHEVTSPQAFDMLRERGLKVAYPERTFA
TMDHIVPTRSQQRPFADSQAELMMQAIEKNTKEFGVNFFNFETGKQGIVHIIGPEMGLTQ
PGMTIACGDSHTSTHGAFGTLAFGIGTSQVRDVLASQCLAMDPMKVRRIEINGELKPGVT
PKDVILYIINRLGVKGGLGYAYEYAGDVFDNMSMEGRMTVCNMSIEGGARAGYVNPDDTT
FDYLKGREYCPQGAEWDAAVEKWRNLASDADAEYDDVVVYDAADIEPMVTWGVTPGQSVG
ISQTLPDPAVVADSGERKAAELAFKHMSLQPGQDMKGVAIDVAFLGSCTNGRIEDLRAAA
EVVRGQKVAESVHAFVVPGSMQVAKQAVKEGLHQIFMDAGFEWRAAGCSMCLAMNPDKLQ
GNQISASSSNRNFIGRQGSSTGRTLLMSPQMVAAAAITGKVVDIREFAGSGAKEAVNV
NT seq 1437 nt   +upstreamnt  +downstreamnt
atggcgaaacgaacattatataacaaggtgtgggatcagcatgcggtgaccaggctgccg
tccgggcagacacagctgtttatcgggctgcatatggtacacgaggttaccagtccgcag
gcgtttgatatgctgcgcgaacggggcctgaaggtggcgtatccggaacggacctttgcg
acaatggatcatatcgtgccgaccaggagccagcagcggccgtttgcggattcccaggcc
gagctgatgatgcaggcgatcgagaagaataccaaggagttcggggtgaacttctttaat
ttcgagaccggcaagcaggggatcgtgcatattatcgggccggagatgggcctgacccag
ccggggatgacgattgcctgcggcgactcgcacaccagtacccacggggcctttggcacc
ctggccttcgggatcgggacaagccaggtgcgcgatgtactggccagtcagtgtctggcc
atggatccgatgaaggtacggcgtatcgagataaacggggaactgaagcccggggttacc
ccgaaggatgtcatcctgtacatcatcaatcgcctgggcgtaaagggcggcctgggctat
gcctatgagtatgccggggatgtgttcgacaacatgagtatggaaggccggatgacggtc
tgcaacatgtcgatcgagggcggcgcccgcgccggatatgtaaaccccgacgacaccacc
tttgattacctgaaggggcgtgagtactgcccgcagggggcggaatgggatgcagcagtc
gagaagtggcgcaacctggccagcgacgcagacgccgagtacgacgatgtggtggtttac
gatgcagcagatatcgagcctatggtaacctggggggtaaccccggggcagagtgtgggg
atatcacagaccctgccggaccccgcggttgttgctgactccggtgagcgcaaggcggcc
gagctggcattcaaacacatgagcctgcagccgggccaggatatgaagggcgtggcaatc
gatgtcgccttcctgggcagctgcacgaacggacggatcgaggatctgcgggccgccgcc
gaggtggtgcgcgggcagaaggtcgccgagagcgtacatgcctttgtggtaccgggatcg
atgcaggtagccaagcaggcggtcaaggaagggctgcatcagatctttatggatgccggt
tttgagtggcgtgctgccggatgctccatgtgtctggcgatgaaccctgacaagctgcag
ggcaaccagatcagtgccagctcgagcaaccgcaactttatcgggcggcagggaagctcg
accgggcgcaccctgctgatgtcaccccagatggtggcggcggcggccatcaccggcaag
gtggtggatattcgcgagtttgccggcagcggcgcaaaggaggcggtaaatgtctaa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (8)   
   KEGG PATHWAY (6)   
   KEGG MODULE (2)   
Chemical substance (19)   
   KEGG COMPOUND (19)   
Chemical reaction (13)   
   KEGG ENZYME (2)   
   KEGG REACTION (11)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (1)   
   Pfam (1)   
All databases (48)   

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