KEGG   Shigella flexneri NCTC1 (serotype 2a): NCTC1_00070
Entry
NCTC1_00070       CDS       T03751                                 
Symbol
leuC
Name
(GenBank) isopropylmalate isomerase large subunit,3-isopropylmalate dehydratase large subunit,isopropylmalate isomerase large subunit,3-isopropylmalate dehydratase large subunit,3-isopropylmalate dehydratase, large subunit,Aconitase family (aconitate hydratase)
  KO
K01703  3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35]
Organism
sft  Shigella flexneri NCTC1 (serotype 2a)
Pathway
sft00290  Valine, leucine and isoleucine biosynthesis
sft00660  C5-Branched dibasic acid metabolism
sft01100  Metabolic pathways
sft01110  Biosynthesis of secondary metabolites
sft01210  2-Oxocarboxylic acid metabolism
sft01230  Biosynthesis of amino acids
Module
sft_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:sft00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00660 C5-Branched dibasic acid metabolism
    NCTC1_00070 (leuC)
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    NCTC1_00070 (leuC)
Enzymes [BR:sft01000]
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.33  3-isopropylmalate dehydratase
     NCTC1_00070 (leuC)
    4.2.1.35  (R)-2-methylmalate dehydratase
     NCTC1_00070 (leuC)
SSDB
Motif
Pfam: Aconitase Spo0M
Other DBs
NCBI-ProteinID: CDX05366
UniProt: Q821C2
Position
1:complement(76792..78192)
AA seq 466 aa
MAKTLYEKLFDAHVVYEAENETPLLYIDRHLVHEVTSPQAFDGLRAHGRPVRQPGKTFAT
MDHNVSTQTKDINACGEMARIQMQELIKNCKEFGVELYDLNHPYQGIVHVMGPEQGVTLP
GMTIVCGDSHTATHGAFGALAFGIGTSEVEHVLATQTLKQGRAKTMKIEVQGKAAPGITA
KDIVLAIIGKTGSAGGTGHVVEFCGEAIRDLSMEGRMTLCNMAIEMGAKAALVAPDETTF
NYVKGRLHAPKGKDFDDAVAYWKTLQTDEGATFDTVVTLQAEEISPQVTWGTNPGQVISV
NDNIPDPASFADPVERASAEKALAYMGLKPGIPLTEVAIDKVFIGSCTNSRIEDLRAAAE
IAKGRKVAPGVQALVVPGSGPVKAQAEAEGLDKIFIEAGFEWRLPGCSMCLAMNNDRLNP
GERCASTSNRNFEGRQGRGGRTHLVSPAMAAAAAVTGHFADIRNIK
NT seq 1401 nt   +upstreamnt  +downstreamnt
atggctaaaacgttatacgaaaaattattcgacgctcacgtagtgtacgaagccgaaaac
gaaaccccgctgttatatatcgaccgccacctggtgcatgaagtgacctcaccgcaggcg
ttcgatggtctgcgcgcccacggtcgcccggtacgtcagccgggcaaaaccttcgccact
atggatcacaacgtctctacccagaccaaagacattaatgcctgtggtgaaatggcgcgc
atccagatgcaggagctgattaaaaactgcaaagaatttggcgtcgagctgtatgacctg
aatcacccgtatcaggggatcgtccacgtaatggggccggaacagggcgtcaccttgccg
gggatgaccattgtctgcggcgactcgcataccgccacccacggcgcgtttggcgcactg
gcctttggtatcggcacttccgaagttgaacacgtactggcaacacaaaccctgaaacag
ggccgtgcgaagaccatgaaaattgaagtccagggcaaagccgcgccgggcattaccgca
aaagatatcgtgctggcaattatcggtaaaactggcagcgcaggcggcaccgggcatgtg
gtggagttttgcggcgaagcaattcgtgatttaagcatggaaggtcgtatgaccctgtgc
aatatggcgatcgaaatgggcgcaaaagccgctctggttgctcctgacgaaaccaccttt
aactatgtcaaaggccgtctgcatgcgccgaaaggcaaagatttcgacgacgccgttgcc
tactggaaaaccctgcaaaccgacgaaggcgcaactttcgataccgttgtcactctgcaa
gcagaagaaatttcaccgcaggtcacctggggcaccaatcccggccaggtgatttctgtg
aacgacaatattcccgatccggcttcgtttgccgatccggttgaacgtgcgtcggcagaa
aaagcgctggcctatatggggctgaaaccgggtattccgctgaccgaagtggctatcgac
aaagtgtttatcggttcctgtaccaactctcgcattgaagatttacgcgcggcagcggag
atcgccaaagggcgaaaagtcgcgccaggcgtgcaggcactggtggttcccggctctggc
ccggtaaaagcccaggcggaagcggaaggtctggataaaatatttattgaagccggtttt
gaatggcgcttgcctggctgctcaatgtgtctggcgatgaacaacgaccgtctgaatccg
ggcgaacgttgtgcatccaccagcaaccgtaactttgaaggccgccaggggcgcggcggg
cgcacgcatctggtcagcccggcaatggctgccgctgctgctgtgaccggacatttcgcc
gacattcgcaacattaaataa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (8)   
   KEGG PATHWAY (6)   
   KEGG MODULE (2)   
Chemical substance (19)   
   KEGG COMPOUND (19)   
Chemical reaction (13)   
   KEGG ENZYME (2)   
   KEGG REACTION (11)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   SWISS-PROT (1)   
Protein domain (2)   
   Pfam (2)   
All databases (50)   

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