KEGG   Shigella flexneri NCTC1 (serotype 2a): NCTC1_04759
Entry
NCTC1_04759       CDS       T03751                                 
Symbol
hpaE
Name
(GenBank) 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase,Betaine aldehyde dehydrogenase,betaine aldehyde dehydrogenase,Delta 1-pyrroline-5-carboxylate dehydrogenase,5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase,Aldehyde dehydrogenase family
  KO
K00151  5-carboxymethyl-2-hydroxymuconic-semialdehyde dehydrogenase [EC:1.2.1.60]
Organism
sft  Shigella flexneri NCTC1 (serotype 2a)
Pathway
sft00350  Tyrosine metabolism
sft01100  Metabolic pathways
sft01120  Microbial metabolism in diverse environments
sft01220  Degradation of aromatic compounds
Module
sft_M00533  Homoprotocatechuate degradation, homoprotocatechuate => 2-oxohept-3-enedioate
Brite
KEGG Orthology (KO) [BR:sft00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00350 Tyrosine metabolism
    NCTC1_04759 (hpaE)
Enzymes [BR:sft01000]
 1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.1  With NAD+ or NADP+ as acceptor
    1.2.1.60  5-carboxymethyl-2-hydroxymuconic-semialdehyde dehydrogenase
     NCTC1_04759 (hpaE)
SSDB
Motif
Pfam: Aldedh
Other DBs
NCBI-ProteinID: CDX09812
UniProt: A0A9P2N119
Position
1:complement(4473732..4475198)
AA seq 488 aa
MKKVNHWINGKNVAGNDYFQTTNPATGEVLADVASGGEAEINQAVAAAKEAFPKWADLPM
KERARLMRRLGDLIDQNVPEIAAMETADTGLPIHQTKNVLIPRASHNFEFFAEVCQQMNG
KTYPVDDKMLNYTLVQPVGVCALASPWNVPFMTATWKVAPCLALGNTAVLKMSELSPLTA
DRLGELALEAGIPAGVLNVVQGYGATAGDALVRHHDVRAVSFTGGTATGRNIMKNAGLKK
YSMELGGKSPVLIFEDADIERALDAALFTIFSINGERCTAGSRIFIQQSIYPEFVKRFAE
RANRLRVGDPNDPNTQVRALISQQHWEKVSGYIRLGIEEGATLLAGGPDKPSDLPAHLKG
GNFLRPTVLADVDNRMRVAQEEIFGPVACLLPFKDEAEGLRLANDVEYGLASYIWTQDVS
KVLRLARGIEAGMVFVNTQNVRDLRQPFGGVKASGTGREGGEYSFEVFAEMKNVCISMGD
HPIPKWGV
NT seq 1467 nt   +upstreamnt  +downstreamnt
atgaaaaaagtaaatcattggatcaacggcaaaaatgttgcaggtaacgactacttccag
actaccaatccggcaacgggtgaagtgctggcggatgtggcctctggcggtgaagcggag
atcaatcaggcggtagcggcagcgaaagaggcgttcccgaaatgggctgatctgccgatg
aaagagcgtgcgcgcctgatgcgccgtctgggcgatctgatcgaccagaacgtgcctgag
atcgccgcgatggaaaccgcggacacgggcctgccgatccatcagaccaaaaatgtgttg
atcccacgcgcttctcacaactttgaatttttcgcggaagtctgccagcagatgaacggc
aagacctatccggttgacgacaagatgctcaactacacgctggtgcaaccggtaggcgtt
tgtgcgctggcgtcgccgtggaacgtgccgtttatgaccgccacctggaaggtcgcgccg
tgtctggcgctgggcaataccgcggtgctgaagatgtcggaactctccccgctgaccgcc
gaccgcctgggtgagctggcgctggaagctggtattccggcgggcgtgctaaacgtggta
cagggctacggcgcaaccgcaggcgatgcgctggtccgtcatcatgacgtgcgtgccgtg
tcgttcaccggcggtaccgccaccgggcgcaacatcatgaaaaacgccgggctgaaaaaa
tactccatggagctgggcggtaaatcaccggtgctgatttttgaagatgccgatattgag
cgtgcgctggacgccgccctgttcaccatcttctcaatcaacggcgaacgctgcaccgcc
ggttcgcgcatctttattcagcagagcatctatccagaattcgttaaacgctttgccgaa
cgcgccaaccgtctgcgcgtgggcgatccgaacgatccgaatacccaggttagggcgctt
atcagtcagcaacactgggaaaaagtctccggctatatccgtctcggcattgaagaaggc
gcaaccctgttggcgggcggcccggataaaccgtccgacctgcctgcgcacctgaaaggc
ggcaacttcctgcgcccaacggtgctggcggacgtagataaccgtatgcgcgttgcccag
gaagagattttcgggccggtcgcctgcctgctgccgtttaaagacgaagccgaaggctta
cgcctggcaaacgacgtggagtacggcctcgcgtcgtacatctggacacaggatgtcagc
aaagtgttacgcctggcgcgtggcattgaagcaggcatggtgttcgtcaacacccagaac
gtgcgcgacctgcgccagccatttggcggcgtaaaagcctccggcaccgggcgtgaaggc
ggtgagtacagcttcgaagtgttcgcggaaatgaagaacgtctgcatttccatgggcgac
catccaattccgaaatggggagtctga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (5)   
   KEGG PATHWAY (4)   
   KEGG MODULE (1)   
Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (1)   
   Pfam (1)   
All databases (21)   

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