KEGG   Sarcophilus harrisii (Tasmanian devil): 100913854
Entry
100913854         CDS       T02286                                 
Symbol
ARHGEF12
Name
(RefSeq) rho guanine nucleotide exchange factor 12 isoform X1
  KO
K07532  Rho guanine nucleotide exchange factor 12
Organism
shr  Sarcophilus harrisii (Tasmanian devil)
Pathway
shr04270  Vascular smooth muscle contraction
shr04360  Axon guidance
shr04611  Platelet activation
shr04625  C-type lectin receptor signaling pathway
shr04810  Regulation of actin cytoskeleton
shr05135  Yersinia infection
shr05152  Tuberculosis
shr05163  Human cytomegalovirus infection
shr05200  Pathways in cancer
shr05205  Proteoglycans in cancer
Brite
KEGG Orthology (KO) [BR:shr00001]
 09140 Cellular Processes
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    100913854 (ARHGEF12)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    100913854 (ARHGEF12)
   04625 C-type lectin receptor signaling pathway
    100913854 (ARHGEF12)
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    100913854 (ARHGEF12)
  09158 Development and regeneration
   04360 Axon guidance
    100913854 (ARHGEF12)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100913854 (ARHGEF12)
   05205 Proteoglycans in cancer
    100913854 (ARHGEF12)
  09172 Infectious disease: viral
   05163 Human cytomegalovirus infection
    100913854 (ARHGEF12)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    100913854 (ARHGEF12)
   05152 Tuberculosis
    100913854 (ARHGEF12)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:shr04131]
    100913854 (ARHGEF12)
Membrane trafficking [BR:shr04131]
 Others
  Rho GTPase associated proteins
   Rho guanine nucleotide exchange factors (GEFs)
    100913854 (ARHGEF12)
SSDB
Motif
Pfam: RGS-like PH_16 RhoGEF PDZ PDZ_6 PDZ_2 PH_13 Tricorn_PDZ
Other DBs
NCBI-GeneID: 100913854
NCBI-ProteinID: XP_031816016
Ensembl: ENSSHAG00000017964
Position
3:360606283..360770508
AA seq 1537 aa
MSGTQPTITDRFPLKKPIRHASILTRESPTDKKQKVERSTSHDFDPTDSSSKKTKSSSEE
SRSETYGLVQRCVIIQKDDNGFGLTVSGDNPVFVQSVKEDGAAMRAGVQTGDRIIKVNGT
LVTHSNHLEVVKLIKSGSYVALTVQGRPPGSPQIPLADSEVEPAAFGHMSPIMTSPHSPG
TSGNTERITSPVLMGEENNVVHNQKVEILRKMLQQEQERLQFLQEDYSRTPAQRLLKEIQ
EAKKHIPQLQEQLSKATGSTQDGAVVLSSKTSGDSLPLSEVEADSGDGLGRIDYSSGDGS
RPNSDIADSPRSGLKERIYLEESPEKSEMIPDNDTQSNIGSPLIRTAPQIIGAEDDDFGT
EHEQINGQCSCFQSIELLRSRPAHLAAFLHHVVSQFDPATLLCYLYSDLYKQTNSKETRR
IFLEFHQFFLDRAAHLKVSVPDEISLDLEKRRPELIPEDLHRHYVQTMQDKVYPEVQKHL
EDFRQKRSMGLTLAESELTKLDAERDRDRVILEKERACAEQIITKIEELLMTAQAVEEDK
SSTMQYVILMYMKHLGVRVKEPRNLEHKRGRIGFLPKIKQSIKKDREGEEKVKRRGFPSI
LGPPRRPSRHDSSAIGRAMELQKQRHPKHLSTPSSVSPEPQDSAKLRQSGISSDAADVMY
MPPNPMSSLTSGTSASQDGGKENEMGSKQIGEGPASGDSTDGTPRTPNTVFDFPAPPLDQ
LQEEEGEIERFPEHGTPKSFRKLDSIAFGESQSEDEQFENDLETDPPNWQQLVSREVLLG
LKPCEIKRQEVINELFYTERAHVRTLKVLDQVFYQRVSREGILSSSELRRIFSNLEEILQ
LHIGLNEQMKAVRKRNETSVIDEIGEDLLIWFSGSGEEKLKHAAATFCSNQPFALEMIKS
RQKKDSRFQTFVQDAESNPLCRRLQLKDIIPTQMQRLTKYPLLLDNIAKYTERPKEREKV
KKAADHCRQILNYVNQAVKEAENKQRLEDYQRRLDTSNLKLSEYPNVEELRNLDLTKRKM
IHEGPLVWKVNRDKTIDLYTLLLEDILVLLQKQDDRLVLRCHSKILASTADSKHTFSPVI
KLNTVLVRQVATDNKALFVISMSDNGAQIYELVAQTVSEKAVWQDLIGRMALTVKEQSTK
PIPLPESPPCEGEREEEEASKLKEESHDVSTSSLQSPEKQMGAETSLMSKPQSPSSVISG
KSEISDLLAERQFEKEQMEETSKESGMDFQSTIPEPHLPVCEERWALDALRNLGLLKQLL
VQQLGLTEKRTPEDWPHFSRFRTSSQGVQVESPGVSQNVLDHSENNKTSQFGEGHTSLQT
RTGQIACYSPRTSIESPVPQDYMELASQDSRASNLLVMDHMIMTPEPSSAELEGGPDDSG
EHFFDAREAHSDDNPSESDGTERKEEEALQLRISGNVLILDGFETVQESSTEEEGVSNLP
SVGWAHQQQSVLNPRSDGGGSPFTPEFLVQQRWRPGEESGFSAQSPSSSADSHSQIMQYI
RKIEADLEHLKKVEESYMTLCQRLAGSALTEEHSDKS
NT seq 4614 nt   +upstreamnt  +downstreamnt
atgagtggcacacagcctactatcacggacaggtttcccctcaaaaaacctataaggcat
gcaagtattttgacccgagagtctccaacagacaagaagcagaaagttgaacgcagtaca
tcacatgactttgaccccacagacagctcctccaagaagacaaagtctagttcagaggag
agtagatcggagacatatggtcttgttcagcgctgtgtgataatccagaaggatgacaat
ggatttgggctgacagtcagtggagacaatccagtcttcgtacagtctgttaaagaagat
ggagcagccatgcgggctggagtacaaacaggtgatcgaatcatcaaggtaaatggaact
ctagtgactcattcaaaccatttggaagtggtaaagctgatcaaatcgggttcctatgta
gctctcactgttcagggacgcccacctgggtcgccccagatcccattagctgattctgaa
gtggagccagcagcctttggacatatgtctcccatcatgacatcaccccattcacctgga
acatctggaaatacagagagaatcaccagtccagtgttgatgggggaagaaaacaatgtg
gttcacaaccagaaagtagaaatactgagaaagatgctacagcaagagcaggaacggcta
cagttcttacaagaagattatagccgcacacctgctcagcgattgcttaaggagattcag
gaggccaagaaacatattcctcagttgcaggaacagttatccaaagcaacaggctcaact
caggatggagctgtagttctatccagcaagacttctggtgactcccttccactcagtgaa
gtagaagcagacagtggtgatgggttaggcagaattgattatagtagtggagatggttct
cgacccaatagtgacattgcggatagtcccagaagtggcttgaaggaaaggatttatcta
gaagaaagtccagagaaaagtgagatgataccagataatgacactcaatcaaacattggt
agtcccttaattcgaacagcacctcagatcattggagcggaagatgatgactttggcact
gaacatgaacagattaatggacaatgcagctgcttccaaagtattgaactgctgagatcc
cgccctgctcacctagctgcattcctacaccatgtagtttcacagttcgaccctgcaaca
ctgctctgttatctttattcagatttatataaacaaaccaattccaaggagactcggcgc
attttccttgagtttcatcagttctttttggaccgagcagcacacttgaaggtttctgtt
ccagatgaaatatctctagacctggagaagagaaggccagaacttattcctgaagatttg
caccgacattatgtccaaactatgcaagataaagtttatcctgaagttcagaaacatttg
gaagattttaggcagaaacgtagtatggggctaaccttagctgaaagtgagctgaccaaa
cttgatgcagaacgagaccgtgaccgtgtaatcttggagaaagaacgagcatgtgcagag
cagatcattaccaaaattgaagaattattgatgacagctcaggctgttgaagaagataag
agttcaacaatgcaatatgtgatcctcatgtacatgaaacatttgggagtcagagtaaaa
gagcctcggaatttggagcataagcgaggtcgcattggatttctgccaaaaatcaagcaa
agtataaagaaagatagggaaggcgaagaaaaagtaaagagaagaggattcccaagcatt
ttaggacccccaaggaggccaagccgtcatgacagcagtgcaattggcagagccatggaa
ttacaaaaacaacgccatcctaagcacttatccacaccctcatcagtgagtcctgaacct
caggactctgccaagttacgccagagtgggatctccagtgatgcagcagatgttatgtat
atgcctcctaatcccatgtcttctttgacttcagggactagtgcctcccaagatggagga
aaagagaatgaaatggggtcaaaacagattggagaaggaccagcttccggagattctaca
gatggtacaccacgaactcctaatacagtctttgattttccagctccaccattagaccaa
ttgcaggaggaggaaggtgaaatagaaaggttccctgaacatggaacaccaaaatctttt
cggaagcttgatagtatagcttttggggaaagtcagagtgaagatgagcagtttgaaaat
gacttagaaacagatccaccaaattggcagcagcttgttagcagagaggtgctcttgggg
ctaaaaccttgtgagatcaaacggcaggaagtgatcaatgagttgttctacacagagcga
gctcatgtccggacactgaaagttctagatcaggtgttctaccagcgagtatcccgagag
gggattctgtcatcgtcagaactgagaagaatcttctccaatctagaagagattcttcag
cttcacattgggttgaatgaacaaatgaaagctgttcgaaagaggaatgagacttctgta
attgatgagattggagaagatttattgatctggttcagtggatcaggagaggagaagttg
aaacatgcagctgccaccttctgtagtaaccagccttttgccctggaaatgatcaaatct
cgtcagaaaaaggactctcgattccagacttttgtgcaggatgctgagagtaatccacta
tgccgtcgactgcagctaaaggatattattcctactcaaatgcagaggctcactaaatat
ccccttctgctggataatattgctaaatatacagaacggccaaaggaaagagaaaaggta
aagaaagcagcagatcactgtcgtcaaatcctaaattatgtgaatcaagctgtcaaggag
gcagagaacaaacagcgcttagaagattatcagcgccgccttgatacatctaacttgaag
ctgtcagagtatccaaatgttgaagagctcaggaatttggatttaacaaagaggaagatg
attcatgaaggaccattagtgtggaaggtgaatagagataagaccattgatctttacaca
ttgctgttggaagacatccttgtattgttacaaaagcaggatgatagactggtgttgagg
tgtcatagtaaaattctagcatctacagcagatagcaaacacacattcagccctgtaatc
aaattgaataccgtgttggttcgacaagttgcaacagataacaaagcattattcgtcatc
tctatgtcagacaatggagcccaaatttatgaattggtggcacagacagtttctgaaaaa
gcagtctggcaggacttgattggcaggatggccctgacagtaaaggaacagtctacaaag
cccatcccattaccagagtcacccccctgcgaaggggaacgtgaggaagaagaagcttca
aagctgaaggaggaatcgcatgatgtttctacctctagtcttcagagtccagaaaaacaa
atgggagcagaaacttctttaatgtcaaaacctcagtccccttcatcagttatatctgga
aaatcagaaatcagtgatctactggctgaaagacagtttgaaaaggaacaaatggaagag
acatctaaagagtctggaatggactttcagagtactatcccagagccacatctccctgtt
tgtgaagagcgctgggcactggatgcactcaggaacttgggtctgttgaagcagttgctg
gtacagcagctaggtttgactgagaagaggactcctgaagactggccacatttttccagg
tttaggacatcttctcagggggtgcaagtagaaagtccaggtgtgagccaaaatgtcttg
gaccactctgaaaataataagaccagccagtttggtgaagggcatacgtccctccaaacc
agaactggccaaattgcatgttacagcccaaggacttcaattgaatctccagttccacag
gattatatggaactggcatctcaagatagcagggcaagtaatcttttagtcatggaccac
atgatcatgaccccagagccgtctagtgcagagctagaagggggtcctgatgacagcgga
gagcacttttttgatgcccgtgaagcccacagtgatgataatccttcagaaagtgatggg
acagaaagaaaggaagaggaagctcttcagttacggatctcaggaaatgttctgatcctt
gatggctttgaaacagttcaggaaagctctacggaggaagaaggtgtttcaaacctccct
tctgtgggctgggctcaccagcagcaatctgttctcaatccccggtctgatggaggaggt
tctccattcactcctgaattcctagtccagcagcgctggagacctggagaggagtctggc
ttcagtgcccagagtccctcttcctctgcagattcacacagccagatcatgcagtacatt
cggaagatagaggctgaccttgaacacttaaagaaagtggaggaaagttacatgactctt
tgccaaaggctggctggatcagccctcacagaggagcactcagataaaagttaa

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (10)   
   KEGG PATHWAY (10)   
Genome (1)   
   KEGG GENOME (1)   
Gene (22)   
   KEGG ORTHOLOGY (1)   
   RefGene (17)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (2)   
   RefSeq(pep) (2)   
DNA sequence (2)   
   RefSeq(nuc) (2)   
Protein domain (8)   
   Pfam (8)   
All databases (47)   

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