KEGG   Sarcophilus harrisii (Tasmanian devil): 100924664
Entry
100924664         CDS       T02286                                 
Symbol
IL6R
Name
(RefSeq) interleukin-6 receptor subunit alpha
  KO
K05055  interleukin 6 receptor
Organism
shr  Sarcophilus harrisii (Tasmanian devil)
Pathway
shr01521  EGFR tyrosine kinase inhibitor resistance
shr04060  Cytokine-cytokine receptor interaction
shr04061  Viral protein interaction with cytokine and cytokine receptor
shr04066  HIF-1 signaling pathway
shr04151  PI3K-Akt signaling pathway
shr04630  JAK-STAT signaling pathway
shr04640  Hematopoietic cell lineage
shr04659  Th17 cell differentiation
shr04932  Non-alcoholic fatty liver disease
shr05163  Human cytomegalovirus infection
shr05171  Coronavirus disease - COVID-19
shr05200  Pathways in cancer
Brite
KEGG Orthology (KO) [BR:shr00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    100924664 (IL6R)
   04066 HIF-1 signaling pathway
    100924664 (IL6R)
   04151 PI3K-Akt signaling pathway
    100924664 (IL6R)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    100924664 (IL6R)
   04061 Viral protein interaction with cytokine and cytokine receptor
    100924664 (IL6R)
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    100924664 (IL6R)
   04659 Th17 cell differentiation
    100924664 (IL6R)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100924664 (IL6R)
  09172 Infectious disease: viral
   05171 Coronavirus disease - COVID-19
    100924664 (IL6R)
   05163 Human cytomegalovirus infection
    100924664 (IL6R)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    100924664 (IL6R)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    100924664 (IL6R)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors [BR:shr04050]
    100924664 (IL6R)
   04090 CD molecules [BR:shr04090]
    100924664 (IL6R)
Cytokine receptors [BR:shr04050]
 Interleukin receptor families
  IL6/12 receptor family
   100924664 (IL6R)
CD molecules [BR:shr04090]
 Proteins
  100924664 (IL6R)
SSDB
Motif
Pfam: IL6Ra-bind Ig_3 fn3 ig Ig_2 I-set Interfer-bind Ig_5
Other DBs
NCBI-GeneID: 100924664
NCBI-ProteinID: XP_012403604
Ensembl: ENSSHAG00000013873
UniProt: G3WLK1
Position
4:356522199..356588170
AA seq 466 aa
MLSVTPVLLSVLFLALGHGLVPEGCPRLDFPDDMVIQVVGASITLSCVDRVSENNASIHW
KLGDKPIAPQLGRREVVEGKLVLRSVQHSDSGNYSCYLDGHRLRTLFLLLVDPLEEPVFS
CHRKSFFSSIQCEWSPLKKPSPHTKAILLVKQANQKDKIFQRPCHYLPGLQKFSCSLNLK
EGDDSPYLAIICVTNGAVRKSSKIHQLGGYETLQPDPPADITVTAIDRSPHKLKVTWKDP
PSWNSTFYRLQFELRYWAENSTTYTTVKEKHHQLIISDALIGTKHTVQIRALEEFNNGRW
SEWSKEITGTPWTETKTFEVGRKLVISTQVPTTSNNYSTKHSPEDPESISNTQPVPGSTH
LSYTFLLSGGSLVLGMALFIAIIMRYRKKSKLTTLKEGKPNMLPPHSLDQVPEKPQSTTV
LVPLISPSVSASSSEPTNNIPGPSGKDIANTQSLYDITNRDYFFPR
NT seq 1401 nt   +upstreamnt  +downstreamnt
atgctgtctgtcaccccagtgctcctctccgtcctgttcttggctcttgggcatggactg
gtcccagaaggctgccccagactggattttccagatgatatggtgatccaggtggttggt
gcctccatcacgctgagctgcgtggacagggtatcggagaataatgcttctattcactgg
aaactgggagataagcccatagctccccagcttggccgaagggaagtggtggaaggaaag
ctggtgctgaggtcagtgcagcacagtgactcgggaaactactcctgctacctggatggt
cacagattgaggaccctgtttctgctactggttgatcctcttgaagaacctgtgttctcg
tgccatcggaagagtttctttagcagcatccagtgtgaatggagccccctgaaaaaaccc
tccccacacactaaggccatcttgttggtgaaacaggccaatcaaaaagacaagattttt
cagaggccgtgtcactacttgcctggactacagaagttctcctgctccttgaatcttaag
gaaggcgatgactccccctacttggctatcatatgtgttaccaatggggctgtgaggaag
tctagcaaaatccaccagcttgggggttatgaaaccttgcaaccagatcctccagctgac
atcacagtcacagccatagacagaagcccccataagcttaaagtcacctggaaagatcca
ccttcctggaactccactttctaccggctccaatttgagcttcgttattgggctgagaac
tccacaacttatacaaccgtcaaggagaagcatcatcagttgattatcagtgatgccttg
atcggcacaaagcatactgtgcagattcgggccctggaggagtttaacaatggcagatgg
agtgaatggagcaaggagatcacgggcaccccgtggacagaaaccaagacctttgaagtt
gggagaaaattagtcatctctacacaggtgcctactacctcaaataactacagtacgaaa
cactccccagaagaccctgaaagcatctctaacactcagccagttcctggctctactcat
ttatcctacacattcctactatctggtggaagtctggtcttgggaatggctctattcatt
gcaattatcatgaggtacagaaaaaagtcgaagctgacaactttgaaagaaggaaagcca
aacatgctccctccacattctttggatcaggtccctgagaagccccaatcaaccacggtt
ttggttcccctcatctctccatctgtgtctgccagtagctctgagcctaccaataacatc
ccagggcccagcggaaaagacattgcgaacacccagagtctttatgacataaccaacaga
gattactttttcccaaggtag

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (12)   
   KEGG PATHWAY (12)   
Genome (1)   
   KEGG GENOME (1)   
Gene (20)   
   KEGG ORTHOLOGY (1)   
   RefGene (15)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (8)   
   Pfam (8)   
All databases (47)   

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