KEGG   Streptomyces leeuwenhoekii: sle_35370
Entry
sle_35370         CDS       T04414                                 
Symbol
sle_35370
Name
(GenBank) Pyruvate dehydrogenase E1 component subunit alpha
  KO
K00166  2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:1.2.4.4]
Organism
sle  Streptomyces leeuwenhoekii
Pathway
sle00280  Valine, leucine and isoleucine degradation
sle00640  Propanoate metabolism
sle00785  Lipoic acid metabolism
sle01100  Metabolic pathways
sle01110  Biosynthesis of secondary metabolites
sle01210  2-Oxocarboxylic acid metabolism
Brite
KEGG Orthology (KO) [BR:sle00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00640 Propanoate metabolism
    sle_35370 (sle_35370)
  09105 Amino acid metabolism
   00280 Valine, leucine and isoleucine degradation
    sle_35370 (sle_35370)
  09108 Metabolism of cofactors and vitamins
   00785 Lipoic acid metabolism
    sle_35370 (sle_35370)
Enzymes [BR:sle01000]
 1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.4  With a disulfide as acceptor
    1.2.4.4  3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
     sle_35370 (sle_35370)
SSDB
Motif
Pfam: E1_dh DXP_synthase_N TPP_enzyme_C
Other DBs
NCBI-ProteinID: CQR62998
UniProt: A0A0F7VX71
Position
chromosome:complement(4190922..4192082)
AA seq 386 aa
MTVMDQRGAYRPSPPPAWQPRTDPAPLLPDPEPYRVLGTEAAGQADPELLRTLYAHLVRG
RRYNAQATALTKQGRLAVYPSSTGQEACEVAAALALKEQDWLFPSYRDTLAVVARGVDPV
QALTLLRGDWHTGYDPREHRVAPLCTPLATQLPHAVGLAHAARLKGDDVVALAMVGDGGT
SEGDFHEALNFAAVWQAPVVFLVQNNGFAISVPLAKQTAAPSLAHKAVGYGMPGRLVDGN
DAAAVHEVLTDAVRHARAGGGPTLVEAITYRVDAHTNADDATRYRGDAEVDTWREHDPIL
LLERELTARGLLDEDAMRAAREDAEAMAADLRARMHQDPVLDPMDLFDHVYAEPTPQLRE
QRAQLRAELEAEAEAGPAPRPEGALR
NT seq 1161 nt   +upstreamnt  +downstreamnt
atgacggtcatggaccagcggggcgcgtaccggccatcaccgccgcccgcctggcagccc
cgaaccgaccccgcgccgctgctgcccgacccggagccgtaccgcgtcctgggcaccgag
gcggccggccaggccgacccggagctgctgcggacgctctacgcccacctggtccgcggc
cgccgttacaacgcgcaggccaccgccctcaccaagcagggccgcctcgccgtctacccc
tccagcaccggccaggaagcctgcgaggtcgccgccgcgctggcgctgaaggagcaggac
tggctcttcccgagctatcgcgacacgctcgccgtcgtcgcccgcggcgtcgacccggtc
caggccctcaccctgctgcgcggcgactggcacaccggctacgacccgcgcgagcaccgc
gtcgccccgctgtgcacgccgctggccacccagcttccgcacgcggtcggcctggcgcac
gccgcccgcctcaagggcgacgacgtggtcgcgctggccatggtcggcgacggcggcacc
agcgagggcgacttccacgaggcgctgaacttcgccgccgtctggcaggccccggtcgtc
ttcctggtgcagaacaacggcttcgccatctccgtcccgctcgccaagcagaccgcggcc
ccgtcgctggcccacaaggccgtcggctacgggatgcccggccgcctggtggacggcaac
gacgccgcggccgtgcacgaggtcctcaccgacgccgtacggcacgcgcgcgcggggggc
ggcccgacgctcgtggaggcgatcacctaccgggtcgacgcgcacaccaacgccgacgac
gccacccgctaccggggggacgccgaggtggacacctggcgggagcacgatccgatcctg
ctgctggagcgggagctgaccgcgcggggcctgctcgacgaggacgcaatgcgcgcggcc
cgggaggacgccgaggccatggccgccgatctgcgcgcgcggatgcaccaggacccggtg
ctcgaccccatggacctgttcgaccacgtgtacgccgagcccaccccgcagctcagggag
cagcgcgcgcagctccgcgccgagctggaggccgaggcggaggccgggccggcgccgcgg
ccggaaggagcgctgcgatga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (7)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1)   
Chemical substance (22)   
   KEGG COMPOUND (22)   
Chemical reaction (15)   
   KEGG ENZYME (1)   
   KEGG REACTION (14)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (3)   
   Pfam (3)   
All databases (54)   

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