ID NOP9_TRIVH Reviewed; 716 AA.
AC D4D9R6;
DT 03-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT 18-MAY-2010, sequence version 1.
DT 22-FEB-2023, entry version 41.
DE RecName: Full=Nucleolar protein 9;
DE AltName: Full=Pumilio domain-containing protein NOP9;
GN Name=NOP9; ORFNames=TRV_03859;
OS Trichophyton verrucosum (strain HKI 0517).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Arthrodermataceae; Trichophyton.
OX NCBI_TaxID=663202;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HKI 0517;
RX PubMed=21247460; DOI=10.1186/gb-2011-12-1-r7;
RA Burmester A., Shelest E., Gloeckner G., Heddergott C., Schindler S.,
RA Staib P., Heidel A., Felder M., Petzold A., Szafranski K., Feuermann M.,
RA Pedruzzi I., Priebe S., Groth M., Winkler R., Li W., Kniemeyer O.,
RA Schroeckh V., Hertweck C., Hube B., White T.C., Platzer M., Guthke R.,
RA Heitman J., Woestemeyer J., Zipfel P.F., Monod M., Brakhage A.A.;
RT "Comparative and functional genomics provide insights into the
RT pathogenicity of dermatophytic fungi.";
RL Genome Biol. 12:R7.1-R7.16(2011).
CC -!- FUNCTION: RNA-binding nucleolar protein required for pre-rRNA
CC processing. Involved in production of 18S rRNA and assembly of small
CC ribosomal subunit (By similarity). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the NOP9 family. {ECO:0000305}.
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DR EMBL; ACYE01000197; EFE41424.1; -; Genomic_DNA.
DR RefSeq; XP_003022042.1; XM_003021996.1.
DR AlphaFoldDB; D4D9R6; -.
DR SMR; D4D9R6; -.
DR GeneID; 9578926; -.
DR KEGG; tve:TRV_03859; -.
DR HOGENOM; CLU_008720_1_1_1; -.
DR OrthoDB; 5477111at2759; -.
DR Proteomes; UP000008383; Unassembled WGS sequence.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 3.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR040000; NOP9.
DR InterPro; IPR001313; Pumilio_RNA-bd_rpt.
DR PANTHER; PTHR13102; NUCLEOLAR PROTEIN 9; 1.
DR PANTHER; PTHR13102:SF0; NUCLEOLAR PROTEIN 9; 1.
DR SMART; SM00025; Pumilio; 6.
DR SUPFAM; SSF48371; ARM repeat; 2.
DR PROSITE; PS50302; PUM; 6.
PE 3: Inferred from homology;
KW Nucleus; Repeat; Ribosome biogenesis; rRNA processing.
FT CHAIN 1..716
FT /note="Nucleolar protein 9"
FT /id="PRO_0000407835"
FT REPEAT 110..145
FT /note="Pumilio 1"
FT REPEAT 146..181
FT /note="Pumilio 2"
FT REPEAT 305..342
FT /note="Pumilio 3"
FT REPEAT 361..396
FT /note="Pumilio 4"
FT REPEAT 397..433
FT /note="Pumilio 5"
FT REPEAT 534..575
FT /note="Pumilio 6"
FT REPEAT 576..613
FT /note="Pumilio 7"
FT REGION 1..70
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 179..207
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 653..716
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..15
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 16..41
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 51..65
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 179..206
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 672..700
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 716 AA; 80016 MW; 5704D8CD30A94743 CRC64;
MPREKKKRGR RAEKSQSKRK REDEEGSDSP KRQRTTNEDN DVQAGDDYIP LVTHDTEKEQ
EQGQEDDTPF YGLLDTEEQE YFSKASQTLE LNSFEDDDDK RLFIESVYTE AKGKELKIAC
SQSCSRLMEK LIAMSTPDQV KALFEKFSGH FLHLVQHRFA SHCCECLFIR AAPIVTSEME
KPKDKKKDRK QTTETNGEDG EQDEPMNQKP AMDLFLGVVS ELEGNWGYLL TESFASHTIR
VLLLILAGEP LADHSNARVL ASRKKENVDS ITSTAQAELT IRESRQVPAE FNSTLRKMIS
DLSAGLNSTY LQALATHPIG SPVLQVILSI ELGCMGKEKV KDKSSVFRRL VPDDTLETKE
EGVNFLNSLF YDPVGSRLLE TIVRVAPGKF FKTFYKTIIR ERIGSLARNE IASYVVIKVL
ERVSREDLQS AIESILPEIP SLVQRSRLNV IKTIIDRSTV RSADTTSLAK ALESAYGEDG
LVRLKTILGV EATDKDAESV KPKAATSAQH LHGSLLAQAM LQAPGRLATM IQTSFLAAPV
EILIQIAKNS TASRALQEAL KPSKSNTQFR RQLLPQFYGQ MCDLSLDSSG SHVADALWDA
TSDLVFIKQR LAQELVDNES ALRDSFLGRA VWRNWSMDLY KRKRGEWMSR AKGLDNPRVS
APTADSSAEP AKSKLDLARA RYAARAEQQE KPDSREQGPR GKKQALSAPS GLLKAQ
//
