KEGG   Streptococcus pyogenes MGAS8232 (serotype M18): spyM18_0440
Entry
spyM18_0440       CDS       T00079                                 
Symbol
murE
Name
(GenBank) putative UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate ligase
  KO
K05362  UDP-N-acetylmuramoyl-L-alanyl-D-glutamate-L-lysine ligase [EC:6.3.2.7]
Organism
spm  Streptococcus pyogenes MGAS8232 (serotype M18)
Pathway
spm00550  Peptidoglycan biosynthesis
spm01100  Metabolic pathways
Brite
KEGG Orthology (KO) [BR:spm00001]
 09100 Metabolism
  09107 Glycan biosynthesis and metabolism
   00550 Peptidoglycan biosynthesis
    spyM18_0440 (murE)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01011 Peptidoglycan biosynthesis and degradation proteins [BR:spm01011]
    spyM18_0440 (murE)
Enzymes [BR:spm01000]
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.2  Acid-D-amino-acid ligases (peptide synthases)
    6.3.2.7  UDP-N-acetylmuramoyl-L-alanyl-D-glutamate---L-lysine ligase
     spyM18_0440 (murE)
Peptidoglycan biosynthesis and degradation proteins [BR:spm01011]
 Precursor biosynthesis
  Amino acid ligase
   spyM18_0440 (murE)
SSDB
Motif
Pfam: Mur_ligase_M Mur_ligase_C
Other DBs
NCBI-ProteinID: AAL97178
UniProt: Q8P2B4
Position
complement(362776..364221)
AA seq 481 aa
MITIEQLLDILKKDHNFREVLDADGYHYHYQGLSFERLSYDSRQVDGKTLFFAKGATFKA
DYLKEAITNGLQLYISEVDYELGIPVVLVTDIKKAMSLIAMAFYGNPQEKLKLLAFTGTK
GKTTAAYFAYHMLKESYKPAMFSTMNTTLDGKTFFKSQLTTPESLDLFAMMAECVTNGMT
HLIMEVSSQAYLVDRVYGLTFDVGVFLNISPDHIGPIEHPTFEDYFYHKRLLMENSRAVV
INSGMDHFSFLADQVADQEHVFYGPLSDNQITTSQAFSFEAKGQLAGHYDIQLIGHFNQE
NAMAAGLACLRLGASLADIQKGIAKTRVPGRMEVLTMTNHAKVFVDYAHNGDSLEKLLSV
VEEHQTGKLMLILGAPGNKGESRRADFGRVIHQHPNLTVILTADDPNFEDPEDISKEIAS
HIARPVEIISDREQAIQKAMSLCQGAKDAVIIAGKGADAYQIVKGQQVAYAGDLAIAKHY
L
NT seq 1446 nt   +upstreamnt  +downstreamnt
atgataaccattgaacaattattagacattttaaaaaaagaccataattttcgtgaggtt
cttgatgccgacggataccactaccattatcaaggcttaagttttgagcgcttgagttac
gatagccgtcaagtagatggcaagacccttttttttgctaaaggagcaactttcaaagct
gactaccttaaagaagcaatcactaacggattacaactctatatttcagaggtagattac
gagcttggtattcccgttgttttggtcactgatatcaaaaaagctatgagtctaattgcc
atggctttctatggcaaccctcaagaaaagctcaaactactagcttttacaggtactaag
ggaaagacgacggctgcttattttgcctaccacatgttgaaagaatcctataaacctgcc
atgttttctaccatgaataccaccttagatggcaagacctttttcaaatcacaacttaca
actcctgaaagcttggatctttttgctatgatggctgagtgtgtgactaatggcatgacc
cacttgattatggaagtttctagtcaggcttacctcgttgaccgtgtctatgggcttacg
ttcgatgttggggttttcctaaatattagtcctgatcatattggcccaatcgagcatcca
acgtttgaagattatttctatcataagcgtcttttaatggagaatagcagagctgttgtg
atcaatagcgggatggatcatttttcatttctagctgatcaggtagcggatcaagagcat
gtgttttatggtcccttgtctgacaaccagatcaccactagccaagctttctcctttgaa
gctaaaggacaattagctggccattatgacattcaattaattggccattttaaccaagaa
aatgctatggcagctggacttgcctgccttcgtttgggtgctagcctagctgatattcaa
aaaggcatcgctaagactcgcgtcccaggccgtatggaagtcctcaccatgactaatcat
gctaaagtttttgttgattatgcccataatggtgacagcttagaaaaattactcagcgtt
gtggaagaacatcagacaggcaaattaatgttgattttaggtgcaccaggaaataaaggc
gagagcagacgagctgattttggtagggtgattcatcagcatccaaacctcaccgtcatt
ctcactgctgatgaccctaatttcgaggatccagaagatatttcaaaagaaattgccagc
catatcgcacgcccggtagagattattagtgaccgtgagcaagctattcaaaaagccatg
tctctttgccaaggagcaaaagatgctgtgattatcgctgggaaaggcgcagatgcttat
caaattgttaaaggacaacaagtagcttatgctggtgatttagcaatcgccaaacactac
ctctag

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (2)   
   KEGG PATHWAY (2)   
Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   SWISS-PROT (1)   
Protein domain (2)   
   Pfam (2)   
All databases (21)   

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