KEGG   Schizosaccharomyces pombe (fission yeast): SPAC9E9.03
Entry
SPAC9E9.03        CDS       T00076                                 
Symbol
leu2
Name
(RefSeq) putative 3-isopropylmalate dehydratase Leu2
  KO
K01702  3-isopropylmalate dehydratase [EC:4.2.1.33]
Organism
spo  Schizosaccharomyces pombe (fission yeast)
Pathway
spo00290  Valine, leucine and isoleucine biosynthesis
spo01100  Metabolic pathways
spo01110  Biosynthesis of secondary metabolites
spo01210  2-Oxocarboxylic acid metabolism
spo01230  Biosynthesis of amino acids
Module
spo_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:spo00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    SPAC9E9.03 (leu2)
Enzymes [BR:spo01000]
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.33  3-isopropylmalate dehydratase
     SPAC9E9.03 (leu2)
SSDB
Motif
Pfam: Aconitase Aconitase_C
Other DBs
NCBI-GeneID: 2543296
NCBI-ProteinID: NP_594576
PomBase: SPAC9E9.03
Ensembl: SPAC9E9.03
UniProt: O14289
Position
I:4439837..4442513
AA seq 758 aa
MSPSVASPKTLYDKVWDSHVVDLQEDGTCLLYIDRHLIHEVTSPQAFEGLRTAGRKVRHP
ELALATVDHNIPTDPRKDMKDIASFIHQPDSRTQVLALENNIKEFGLTYYGMNDRRQGIV
HVIGPEQGFTLPGTTLVCGDSHTSTHGAFGALAFGIGTSEVEHVLATQTILQRKSKNMRI
RVNGKLPEGIASKDLILHIIGVIGTAGGTGSVIEFCGEAIEGLSMEARMSMCNMSIEAGA
RAGMIAPDATTFEYVKNRPLAPKGDDWEQAVAYWKTLRSDENAKYDIEVEINAADVLPTV
TWGTSPQDVIPINGNIPDPAHVKDNVRAASIQRSLEYMGLKPNTSIVSYPIDKVFIGSCT
NSRIEDLRLAAAVVKGRKVAANVKDAMIVPGSGLVKKMAEAEGLDQIFIEAGFDWREAGC
SMCLGMNPDQLKPYERCASTSNRNFEGRQGAKGRTHLVSPAMAAAAAIKGHLCNVREFFG
DVSNGSPSIITNKNYDPSHDVEGDIGLSVDDATDAVTDADGIATNVAGSVSSGSAGIPKF
TVVEGIAAPLPMANVDTDKIIPKQFLKTIKRTGLGQFAFYEIRYDADGKEIPDFVLNREP
YRHATVLVAHDNFGCGSSREHAPWALNDFGIRVIIAPSFADIFFNNCFKNGMLPIPTPIE
QVNDMMKAAENQVKFSVDLVNQTITYGDKQVKFDVEPFRKHCLVNGLDDIGLTLQKETMI
DAFEAAREENFPWMNIKRSRARLSPVKSNKQSSSRNDW
NT seq 2277 nt   +upstreamnt  +downstreamnt
atgtctccctcagttgcttctcctaaaactttgtacgacaaggtttgggacagccacgtt
gtcgaccttcaagaggatggtacatgtttgttgtatattgatcgacacttgattcacgaa
gtcacttctcctcaagcctttgagggccttcgtactgctggtagaaaagttcgtcatccc
gaacttgctcttgcaactgtcgatcacaatattcctaccgatcctcgtaaggacatgaag
gatatcgcttccttcattcatcaacctgactcacgcactcaagtcttggctttggaaaat
aacattaaggagtttggtcttacctactatggtatgaatgacagacgtcaaggtatcgtt
cacgttattggtcctgaacagggcttcactctccctggtacgaccctcgtttgtggtgat
tctcacacctctacccacggcgcttttggtgctttggcttttggtatcggtactagtgag
gtcgaacatgtcttggccactcaaaccattttgcaacgcaagagtaaaaacatgcgcatt
cgtgtaaacggtaaattgcctgagggtattgcttctaaggacttgatccttcatattatt
ggagttattggtactgctggtggtactggttccgttattgagttttgcggtgaagctatt
gaaggtttaagtatggaagctcgtatgtccatgtgtaacatgtccattgaggctggtgct
cgcgccggtatgattgctcctgatgcaacgacttttgaatatgttaaaaaccgccctctt
gctcccaagggcgatgattgggaacaggccgtggcttattggaaaaccctccgctccgat
gagaatgctaagtacgatattgaagttgaaatcaatgctgctgatgttttacccactgta
acatggggtacttctcctcaggacgttatccccattaatggtaatatccctgatcccgca
cacgttaaagacaacgtacgtgctgcgtctattcaacgctctctagaatatatgggactc
aaacctaatacctctattgtgtcctatcccatcgacaaagtctttattggctcttgtacc
aattctcgtattgaggatttgcgtcttgctgctgccgttgtcaagggccgtaaggtcgct
gctaacgtaaaagatgctatgattgttccaggctctggtctcgttaaaaaaatggccgaa
gctgaaggattggaccaaatattcattgaagctggatttgattggcgtgaagctggctgt
tcaatgtgtttgggtatgaatcccgatcaactcaagccatatgaacgttgtgcctcaacc
tcaaatcgtaactttgaaggtcgccaaggtgctaagggtagaacgcatcttgttagtccc
gctatggctgccgctgccgctattaaaggacatctctgtaatgttcgtgaattttttgga
gatgtttccaacggatctccttctattattactaacaagaactatgatcccagccatgat
gtagagggtgatataggcctttctgttgacgatgctactgatgcagttactgatgctgat
ggcattgccactaatgttgctggttctgtatcttctggatctgccggtattcccaaattc
accgtcgttgaaggcattgctgctcctttgcctatggctaatgtcgacactgacaaaatt
attcccaagcaatttttgaagaccattaaacgtaccggtcttggtcaatttgctttctac
gaaatccgttacgatgcggacggaaaggagatacccgactttgtcctcaatcgcgaacct
taccgacatgcaactgttttggttgctcacgacaacttcggttgtggtagctctcgtgag
catgctccatgggcattaaacgattttggcattcgtgtaattattgcaccgtcttttgct
gacattttcttcaataactgcttcaagaatggtatgcttcctattcctactccaattgag
caagttaatgatatgatgaaagccgctgaaaatcaagtcaaattctctgtcgatcttgtt
aatcaaactataacttatggtgataaacaagtcaaatttgatgttgagcctttccgtaaa
cattgtttggttaatggtttggatgacatcggactgactttgcaaaaagaaactatgatt
gacgcttttgaggctgctagagaagaaaacttcccttggatgaatatcaagcgcagccgg
gctcgcctttcacctgttaaaagcaataagcaatcttctagcaggaacgattggtga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (6)   
   KEGG PATHWAY (5)   
   KEGG MODULE (1)   
Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (4)   
   KEGG ENZYME (1)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (46)   
   KEGG ORTHOLOGY (1)   
   RefGene (37)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (3)   
   OC (1)   
   POMBASE (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (2)   
   Pfam (2)   
All databases (69)   

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