KEGG T00050: SPy

Streptococcus pyogenes M1 GAS (serotype M1): SPy_1164

Entry

SPy_1164          CDS       T00050

Symbol

topA

Name

(GenBank) putative DNA topoisomerase I

K03168

DNA topoisomerase I [EC:5.6.2.1]

Organism

spy Streptococcus pyogenes M1 GAS (serotype M1)

Brite

KEGG Orthology (KO) [BR:spy00001]
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:spy03032]
    SPy_1164 (topA)
   03400 DNA repair and recombination proteins [BR:spy03400]
    SPy_1164 (topA)
Enzymes [BR:spy01000]
5. Isomerases
  5.6  Isomerases altering macromolecular conformation
   5.6.2  Enzymes altering nucleic acid conformation
    5.6.2.1  DNA topoisomerase
     SPy_1164 (topA)
DNA replication proteins [BR:spy03032]
Prokaryotic type
  DNA Topoisomerases
   SPy_1164 (topA)
DNA repair and recombination proteins [BR:spy03400]
Prokaryotic type
  DSBR (double strand breaks repair)
   NHEJ (non-homologous end-joining)
    SHIIR (short-homology-independent illegitimate recombination)
     Facilitator
      SPy_1164 (topA)

SSDB

Motif

Pfam:

Topoisom_bac zf-C4_Topoisom Toprim C1_2 Toprim_4 DUF2996 HypA

Other DBs

NCBI-ProteinID:

AAK34035

UniProt:

Q99ZM4

Position

956719..958848

AA seq 709 aa
MGTKTTTKPKTGTKKSTTKKKSTAKKNLVIVESPAKAKTIEKYLGRSYKVVASVGHIRDL
KKSSMSIDFDNNYEPQYINIRGKGPLINSLKKEAKAAKKVYLASDPDREGEAISWHLSHI
LGLDPQDNNRVVFNEITKDAVKHAFVEPRQIDMDLVDSQQARRVLDRIVGYSISPILWKK
VKKGLSAGRVQSVALKLIIDRENDIKAFVPKEYWSIDGLFKKGTKKFQATFYGINGKKTK
LDNNNDVKEVLAKLTNEDFLVSKVDKKERRRNAPLPYTTSSLQQDAANKINFRTRKTMMV
AQQLYEGIHLGENGTQGLITYMRTDSTRISPVAQNDAAQFIINRFGANYSKHGNRVKNTS
GVQDAHEAIRPSSVNHTPDSIAKYLNKDQLKLYTLIWNRFVASQMTAAVFDTVKVNLEQN
GVIFVANGSQMKFDGYMAVYNDSDKNKMLPEMAEGETVKKISTSPEQHFTQPPARYSEAT
LIKTLEENGVGRPSTYAPTLEVIQRRYYVKLSAKRFEPTELGEIVNKLIVEFFPDIVDVA
FTAEMEGKLDQVEIGEEQWQHVIDQFYQPFVKELNKAESEIEKIQIKDEPAGFDCDVCGH
PMVIKLGRFGKFYACSNFPECRNTKAITKEIGVTCPVCHKGQVIERKTKKNRIFYGCDQY
PDCEFISWDLPIGRACPKSGDYLIEKKVRGGKQVMCSNETCDYKEEKIK

NT seq 2130 nt +upstreamnt +downstreamnt
ttgggaacaaaaactacaactaagccaaaaacgggtactaaaaagtccaccactaaaaag
aaatcaacagcgaaaaaaaatctcgttattgttgaatcacctgccaaagctaagactatt
gaaaaatatcttggacgcagttataaagttgttgcttcggtaggacatattcgtgactta
aaaaaatcgtctatgtctattgattttgataataattatgagccacaatacattaatatc
cgtggtaagggaccccttatcaattctttaaaaaaagaagccaaagctgctaaaaaagtt
tatttagctagtgacccggatcgtgagggagaggctatttcttggcatttgtcacatatc
ttaggacttgatcctcaagataataaccgagtggtttttaatgaaattacgaaagatgca
gttaaacatgcctttgtggagcctcgtcagattgatatggacttggtagattctcaacaa
gcacgtcgtgttttggaccgtattgtgggatattccatttcaccaattctttggaaaaag
gtcaaaaaaggactttcagcaggacgtgtccagtcggttgctttaaaactcatcattgac
cgtgaaaatgacatcaaagcatttgttccaaaggaatactggtctattgatggtcttttt
aaaaaaggaactaaaaagtttcaagcgactttttacggtattaatggcaaaaaaacaaag
cttgacaataacaacgatgtcaaagaggtattagcaaagctaacaaatgaagattttctt
gtcagcaaggttgacaagaaagagcgacgtcgtaatgctcccttaccttacacaacatca
tctcttcaacaagatgctgctaataaaatcaatttcagaacgcgtaaaaccatgatggta
gcccaacaactgtatgaggggattcatttaggagaaaatggaactcaaggtttaattacc
tatatgcgtacggattctactcgtatcagtccagtagcacaaaacgatgctgctcaattt
attatcaatcgctttggagctaattattcaaaacatggtaatcgtgtcaaaaataccagt
ggtgtccaagatgctcacgaggcgattcgtccatctagtgttaatcatacgccagactct
attgccaaataccttaacaaggatcagttaaaactttatacgcttatttggaatcgtttt
gtggctagccaaatgacagcagctgtttttgataccgtaaaggtgaacttggagcaaaat
ggcgtgatttttgttgccaatggtagccaaatgaagtttgatggttacatggctgtttac
aatgattccgataaaaacaaaatgttacctgagatggcagaaggagaaacggttaaaaaa
atatcgacctctccagaacagcactttacgcagccaccagctcgttattctgaagcaact
ctaattaaaacgctagaagaaaatggtgttggacgtccatcaacttacgctccaacctta
gaagtcattcaacgcagatactatgttaaattgtctgctaagcgctttgagccaactgag
cttggggaaattgtcaacaagcttattgtcgaatttttcccagatattgtcgatgttgcc
tttactgccgagatggaaggtaagctagatcaagttgaaatcggagaagaacaatggcaa
catgttatcgatcaattctatcaaccctttgtcaaagaattgaataaggctgagtctgaa
attgaaaagattcaaatcaaagatgaaccagctggcttcgactgtgatgtttgtggtcac
ccaatggtcattaagttaggacgttttgggaaattttacgcgtgtagcaacttcccagag
tgccgtaatacaaaagccatcactaaagaaattggtgttacttgtccggtttgtcataaa
ggacaagttatcgagcgtaaaaccaaaaaaaataggatattttatggttgtgatcagtat
ccagattgtgagtttatctcgtgggatttacctattggacgtgcttgccctaagtcaggt
gactatcttattgagaaaaaagttcgtggtggcaaacaagtaatgtgtagcaatgagacc
tgtgattacaaggaagaaaaaattaaataa

All links

Ontology (4)   
   KEGG BRITE (4)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (28)   
   KEGG ORTHOLOGY (1)   
   RefGene (25)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (7)   
   Pfam (7)   
All databases (42)   

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