KEGG   Streptococcus pyogenes A20 (serotype M1): A20_0401
Entry
A20_0401          CDS       T02335                                 
Symbol
nrdE
Name
(GenBank) ribonucleoside-diphosphate reductase, alpha subunit
  KO
K00525  ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
Organism
spya  Streptococcus pyogenes A20 (serotype M1)
Pathway
spya00230  Purine metabolism
spya00240  Pyrimidine metabolism
spya01100  Metabolic pathways
spya01232  Nucleotide metabolism
Brite
KEGG Orthology (KO) [BR:spya00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    A20_0401 (nrdE)
   00240 Pyrimidine metabolism
    A20_0401 (nrdE)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03400 DNA repair and recombination proteins [BR:spya03400]
    A20_0401 (nrdE)
Enzymes [BR:spya01000]
 1. Oxidoreductases
  1.17  Acting on CH or CH2 groups
   1.17.4  With a disulfide as acceptor
    1.17.4.1  ribonucleoside-diphosphate reductase
     A20_0401 (nrdE)
DNA repair and recombination proteins [BR:spya03400]
 Prokaryotic type
  Other factors with a suspected DNA repair function
   Modulation of nucleotide pools
    A20_0401 (nrdE)
SSDB
Motif
Pfam: Ribonuc_red_lgC RNR_N Ribonuc_red_lgN Vitelline_membr
Other DBs
NCBI-ProteinID: AFV37488
Position
355364..357544
AA seq 726 aa
MSQTNASYLSLNALTRFKKPDGSYHFDSDKEAVRRYLEEHVSPNQMAFNSLEDKLAYLIN
EGYYEQAIFDAYPNDLIKEAFHYAYQQGYRFLNLMGAMKFYQSYALKTLDGKQYLETFED
RAVMNALFLADGDQTFVFDVIDAILHRRFQPATPTFLNAGKKRRGEYISCYLLRVEDNME
SISRAISTSLQLSKRGGGVALCLTNLREIGAPIKGIENQATGIVPVMKLLEDSFSYANQL
GQRQGAGAVYLHAHHPEVLTFLDTKRENADEKIRIKSLALGLVIPDITFQLAKENKDMAL
FSPYDIKRAYGKDMSDISITEEYDKLLANPAIKKTYISARKFFQLIAELHFESGYPYLLF
DDTVNKRNPHAKKGRIVMSNLCSEIAQVSTPSTFKEDLSFETIGEDICCNLGSINIAQAM
ADAPHFEQLITTSIRALDRVSRVSDLNCAPSVETGNAANHAVGLGAMNLHGFLATNHIYY
DTKEAVDFTDLFFHAMAYYAFKASCQLAKEKGAFAGFSLSTYSDGTYFAKYLQEDAKPQT
AKVATLLQDYGFTLPTVADWQALVADIKQFGLANAHLLAVAPTGSISYLSSCTPSLQPVV
APVEVRKEGSLGRIYVPAYQIDQANYAYYERGAYEVGPKAIIDVVAAAQKHVDQAISLTL
FMTDQATTRDLNRSYIQAFKQNCASIYYVRVRQDVLAGSEQYDEDSLVTAPGASDETTTE
CQSCMI
NT seq 2181 nt   +upstreamnt  +downstreamnt
atgtcacaaaccaatgcgtcatacctctcattaaatgcactgacccgttttaaaaaacca
gacggcagctaccattttgatagcgataaagaagctgttaggcgctacctggaagaacat
gtctctcccaatcaaatggcttttaactcactagaagataagctagcttacctcatcaat
gaagggtattatgagcaggccatttttgatgcctatcctaatgaccttatcaaggaggcc
tttcattatgcctatcaacaaggctatcgctttttaaatctcatgggcgctatgaaattt
taccagtcctatgccttaaaaaccttggacggtaagcagtatctagaaacatttgaagac
cgtgctgtgatgaatgcactctttttagctgatggagatcaaacctttgtctttgacgtg
attgatgccatcttgcaccgacgctttcaaccagctaccccaacgtttttaaatgccgga
aaaaaacgccgtggcgaatacatttcgtgctatcttcttcgtgtcgaagacaatatggaa
tctatctctcgcgccattagcaccagcttgcaactctcaaaaagaggaggcggagtcgcc
ttgtgcctcaccaacctcagagaaatcggagcaccgataaaagggattgaaaatcaggca
acaggcatcgttcctgtcatgaaactactagaggactctttttcctatgccaatcaacta
ggtcagcgccaaggagcaggtgcggtttaccttcatgcccatcaccctgaggttttgacc
tttttagacaccaaacgtgaaaatgccgatgagaaaattcgcattaagtccctagcattg
ggacttgtgatcccagatattaccttccagttagccaaagaaaacaaagacatggcactc
ttttcaccctatgatatcaagcgtgcctatggcaaggacatgtcagacatctccatcaca
gaggaatacgataaactgctagccaatccagccatcaaaaagacctacatcagtgctaga
aagttctttcagttaattgcagagctacattttgagtcaggctacccttacctcttgttt
gatgacacggtcaataagcgcaaccctcatgccaaaaaaggcagaatcgtcatgtctaac
ctgtgttctgaaatcgctcaagttagcaccccaagcactttcaaagaagatttgagtttt
gaaaccattggagaggatatctgctgtaatttagggtctatcaatattgcccaggctatg
gcagatgcgccacactttgaacagctcatcacaacgagcatcagagcacttgatcgtgtc
tctagagtgtctgacctgaattgtgcgccttctgttgagacaggcaatgcagccaaccat
gcagtaggattaggcgccatgaacctacatggttttttggcaaccaaccacatctactat
gatacaaaagaagccgttgactttacagatctgtttttccatgccatggcctattatgct
tttaaagcctcttgccaattagccaaagaaaaaggcgcttttgcaggattttcgttatca
acctattcagatggcacttattttgccaagtatttgcaagaagatgccaagccacaaaca
gccaaggttgccacattgttgcaagattacggcttcacgttgccaacggtggcggattgg
caagccctagtagcagatatcaagcagtttggcctagccaatgcgcacttgctagcggtt
gctccgacaggctccatcagctacttatcatcctgcactccgagtctacaaccagtcgtt
gctcctgttgaggtccgaaaagaaggtagcctgggcaggatttacgtccctgcctatcag
attgaccaggctaactatgcttactatgaacgtggtgcctatgaggtcggcccaaaagcc
atcatcgacgttgtagctgctgcccaaaaacacgttgaccaagccatctcattgaccctg
tttatgaccgatcaagcgaccacacgtgacctgaaccgctcctatatccaagcttttaag
caaaattgtgcatcgatctattatgtgcgagtgaggcaagacgtcctagcaggcagcgaa
cagtatgacgaggatagtcttgtgacagctcctggagctagtgatgagaccaccacagag
tgtcaaagctgtatgatctaa

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (6)   
   KEGG PATHWAY (4)   
   KEGG MODULE (2)   
Chemical substance (11)   
   KEGG COMPOUND (11)   
Chemical reaction (5)   
   KEGG ENZYME (1)   
   KEGG REACTION (4)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein domain (4)   
   Pfam (4)   
All databases (33)   

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