KEGG   Streptomyces reticuli: TUE45_02084
Entry
TUE45_02084       CDS       T04246                                 
Symbol
metH
Name
(GenBank) Methionine synthase
  KO
K00548  5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
Organism
srw  Streptomyces reticuli
Pathway
srw00270  Cysteine and methionine metabolism
srw00450  Selenocompound metabolism
srw00670  One carbon pool by folate
srw01100  Metabolic pathways
srw01110  Biosynthesis of secondary metabolites
srw01230  Biosynthesis of amino acids
srw04980  Cobalamin transport and metabolism
Brite
KEGG Orthology (KO) [BR:srw00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    TUE45_02084 (metH)
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    TUE45_02084 (metH)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    TUE45_02084 (metH)
 09150 Organismal Systems
  09154 Digestive system
   04980 Cobalamin transport and metabolism
    TUE45_02084 (metH)
Enzymes [BR:srw01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     TUE45_02084 (metH)
SSDB
Motif
Pfam: S-methyl_trans Pterin_bind Met_synt_B12 B12-binding_2 B12-binding Tautomerase_2
Other DBs
NCBI-ProteinID: CUW27361
Position
I:complement(2482058..2485573)
AA seq 1171 aa
MASSPTSPSTDSRTRASALREALATRVVVADGAMGTMLQAQEPTLEDFENLEGCNEILNL
TRPDIVRSVHEAYFAVGVDCVETNTFGANHAAMAEYDIADRVHELSEAGARIARETADAF
SARDGRPRWVLGSIGPGTKLPTLGHVGFTTIRDGFQANAEGLLTGGADALIVETTQDLLQ
TKASVLGARRAMDKLGVDVPLLVSMAFETTGTMLLGSEIGAALTALEPLGIDMIGLNCST
GPAEMSEHLRYLTRHSRIPLLCMPNAGLPVLTKDGAHFPLGPEGLADAQENFVRDYGLSL
IGGCCGTTPEHLRQVVERVHGLTPPERDPRPEPGAASLYQSVPFRQDTSYLAIGERTNAN
GSKKFREAMLAGRWDDCVEMAREQIREGAHMLDLCVDYVGRDGVADMEELAGRFATASTL
PIVLDSTEVDVIRAGLEKLGGRAVINSVNYEDGDGPDSRFAKVTQLAREHGAALIALTID
EEGQARTPEKKVEIAERLIADLTGNWGIREEDILIDTLTFTICTGQEESRKDGIATIEAI
RELKRRHPAVQTTLGLSNISFGLNPAARILLNSVFLDECVKAGLDSAIVHASKILPIARF
SEEEVRTALDLIYDRRGEGYDPLQKLMQLFEGATAKSLKAGKAEELAALPLEERLKRRII
DGERNGLEADLDAALRDRPALDIVNETLLDGMKVVGELFGSGQMQLPFVLQSAEVMKAAV
AYLEPHMEKSDAEGKGTIVLATVRGDVHDIGKNLVDIILSNNGYNVVNLGIKQPVSAILE
AAEEHRADVIGMSGLLVKSTVIMKENLEELNQRGLAARFPVILGGAALTRAYVEQDLHEI
YQGEVRYARDAFEGLRLMDALIGVKRGVPGAKLPELRQRRVRPAAAVPVAERPEEGHVRS
DVATDNPVPTPPFWGTRVVKGIQLKEYASWLDEGALFKGQWGLKQARTGEGPTYEELVET
EGRPRLRGLLDRLQTDNLLEAAVVYGYFRCVSKDDDLIILDEQGNERTRFTFPRQRRGRR
LCLADFFRPEESGETDVVGLQVVTVGSRIGEETAKLFETNAYRDYLELHGLSVQLAEALA
EYWHARVRAELGFAGEDPADIQDMFDLKYRGARFSLGYGACPDLEDRAKIADLLQPERIG
VHLSEEFQLHPEQSTDAIVIHHPEAKYFNAR
NT seq 3516 nt   +upstreamnt  +downstreamnt
atggcctcgtcgccgacgtccccttccaccgacagccggacccgtgcgtccgcgctccgc
gaggcgctcgccacccgtgtggtggtcgccgacggagcgatgggcacgatgctccaggcc
caggagccgaccctcgaggacttcgagaacctcgagggctgcaacgagatcctcaacctc
acccgccccgacatcgtccgctccgtccacgaggcgtacttcgccgtgggcgtcgactgc
gtcgagaccaacaccttcggggccaaccacgcggccatggcggagtacgacatcgccgac
cgcgtccacgagctgtccgaggccggcgcccgcatcgcccgcgagaccgccgacgcgttc
tccgcccgcgacggccgcccccgctgggtcctcggctccatcggccccggcaccaagctg
cccaccctcggtcacgtcggcttcaccaccatccgcgacggcttccaggcgaacgccgag
ggcctgctcaccggcggcgccgacgccctgatcgtggagaccacccaggacctgttgcag
accaaggcctccgtgctgggcgcccgccgcgccatggacaagctcggcgtcgacgtcccc
ctgctggtctccatggccttcgagaccaccggcaccatgctgctgggctccgagatcggc
gccgccctcaccgcgctggagccgctcggtatcgacatgatcggcctgaactgctcgacc
ggcccggccgagatgagcgagcacctgcgctacctcacccggcactcccgcatcccgctg
ctgtgcatgcccaacgccggcctgcccgtcctcaccaaggacggcgcccacttcccgctc
ggccccgagggcctggcggacgcccaggagaacttcgtacgcgactacggcctctccctc
atcggcggctgctgcggcaccacccccgaacacctgcgccaggtcgtggagcgcgtgcac
ggcctcaccccgcccgagcgcgacccgcgtcccgagcccggcgccgcctccctctaccag
tccgtcccgttccggcaggacacctcctacctggccatcggcgagcgcaccaacgccaac
ggctccaagaagttccgcgaggccatgctggcgggccgctgggacgactgcgtcgagatg
gcccgggagcagatccgcgagggcgcgcacatgctcgacctgtgcgtcgactacgtcggc
cgggacggcgtcgcggacatggaggagctggccggccgcttcgccaccgcctccaccctg
ccgatcgtgctggactccaccgaggtcgacgtcatccgggccggcctggagaagctcggc
ggccgtgcggtgatcaactcggtgaactacgaggacggcgacggccccgactcccggttc
gcgaaggtcacccagctggcgcgcgagcacggggcggcgctcatcgcgctcaccatcgac
gaggagggccaggcccgcaccccggagaagaaggtcgagatcgccgaacggctgatcgcc
gacctcaccgggaactggggcatccgcgaggaggacatcctcatcgacaccctgaccttc
accatctgcaccggtcaggaggagtcccgcaaggacggcatcgccaccatcgaggccatc
cgcgagctgaagaggcggcaccccgcggtgcagaccacgctgggcctgtcgaacatctcc
ttcggcctcaacccggccgcccgcatcctgctgaactccgtcttcctcgacgagtgcgtc
aaggcgggcctggactccgcgatcgtccacgcctccaagatcctgccgatcgcccgcttc
agcgaggaagaggtccggaccgctctcgacctgatctacgaccgccgcggcgagggctac
gaccccctccagaagctcatgcagctcttcgagggcgccacggcgaagtccctgaaggcc
ggcaaggccgaggaactggccgcgctgcccctggaggagcggctcaagcgccggatcatc
gacggcgagcgcaacggcctggaagccgacctggacgccgccctgcgggaccgcccggca
ctcgacatcgtcaacgagaccctgctggacggcatgaaggtcgtcggcgaactgttcggc
tccggccagatgcagctgccgttcgtcctccagtccgccgaggtcatgaaggccgccgtc
gcctacctcgaaccgcacatggagaagtcggacgccgagggcaagggcacgatcgtgctg
gccaccgtgcgcggcgacgtgcacgacatcggcaagaacctggtcgacatcatcctgtcc
aacaacggctacaacgtcgtcaacctgggcatcaagcagccggtctccgcgatcctggag
gccgccgaggagcaccgggccgatgtgatcggcatgtccgggctgctggtgaagtccacg
gtgatcatgaaggagaacctggaggagctgaaccagcgcggcctcgccgcccgcttcccg
gtcatcctcggcggtgccgccctgacccgggcgtacgtcgagcaggacctgcacgagatc
taccagggcgaggtccgctacgcccgcgacgccttcgagggcctgcgcctgatggacgcc
ctgatcggcgtcaagcggggcgtgcccggtgccaagctgcccgagctgcggcagcgccgg
gtccgcccggccgccgccgtcccggtggccgagcggcccgaggagggccacgtccgctcc
gacgtcgccaccgacaaccccgtgcccaccccgcccttctggggcacccgggtggtcaag
ggcatccagctcaaggagtacgcgagctggctggacgagggcgcgctgttcaagggccag
tggggactgaagcaggcccgcaccggcgagggacccacctacgaggaactggtcgagacc
gagggccggccccggctgcgcggcctgctcgaccggctccagaccgacaacctgctggag
gcggccgtcgtctacggctacttccgctgcgtctccaaggacgacgacctgatcatcctg
gacgagcagggcaacgagcgcacccgcttcaccttcccgcgccagcgccgcggccggcgc
ctgtgcctggccgacttcttccgcccggaggagtccggcgagaccgacgtcgtcggcctc
caggtcgtcaccgtcggctcccgcatcggcgaggagacggccaagctcttcgagaccaac
gcctaccgtgactacctcgaactgcacggcctgtccgtccagttggccgaggccctcgcc
gagtactggcacgcccgcgtccgcgccgaactcggcttcgccggcgaggacccggccgac
atccaggacatgttcgacctgaagtaccgcggggcccgcttctccctcggttacggcgcc
tgccccgacctggaggaccgcgccaagatcgccgacctgctccagcccgagcggatcggc
gtccacctgtccgaggagttccagctgcaccccgagcagtccacggacgccatcgtgatc
caccacccggaggcgaagtacttcaacgctcggtga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (8)   
   KEGG PATHWAY (7)   
   KEGG MODULE (1)   
Chemical substance (8)   
   KEGG COMPOUND (8)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein domain (6)   
   Pfam (6)   
All databases (31)   

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