KEGG   Sus scrofa (pig): 397343
Entry
397343            CDS       T01009                                 
Symbol
ADAM17
Name
(RefSeq) disintegrin and metalloproteinase domain-containing protein 17 precursor
  KO
K06059  disintegrin and metalloproteinase domain-containing protein 17 [EC:3.4.24.86]
Organism
ssc  Sus scrofa (pig)
Pathway
ssc04148  Efferocytosis
ssc04330  Notch signaling pathway
ssc05010  Alzheimer disease
ssc05171  Coronavirus disease - COVID-19
Brite
KEGG Orthology (KO) [BR:ssc00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04330 Notch signaling pathway
    397343 (ADAM17)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    397343 (ADAM17)
 09160 Human Diseases
  09172 Infectious disease: viral
   05171 Coronavirus disease - COVID-19
    397343 (ADAM17)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    397343 (ADAM17)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:ssc01002]
    397343 (ADAM17)
  09183 Protein families: signaling and cellular processes
   04090 CD molecules [BR:ssc04090]
    397343 (ADAM17)
Enzymes [BR:ssc01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.24  Metalloendopeptidases
    3.4.24.86  ADAM 17 endopeptidase
     397343 (ADAM17)
Peptidases and inhibitors [BR:ssc01002]
 Metallo peptidases
  Family M12: astacin/adamalysin family
   397343 (ADAM17)
CD molecules [BR:ssc04090]
 Proteins
  397343 (ADAM17)
SSDB
Motif
Pfam: Reprolysin_5 Reprolysin_2 ADAM17_MPD Disintegrin Reprolysin_3 Reprolysin Reprolysin_4 Pep_M12B_propep
Other DBs
NCBI-GeneID: 397343
NCBI-ProteinID: NP_001093396
Ensembl: ENSSSCG00000008639
UniProt: O77636 A0A8D0LFA7
Position
3:126795513..126853995
AA seq 833 aa
MRQCALFLTSLVPIVLAPRPPDEPGFGSPQRLEKLDSLLSDYDILSLSSIRQHSVRKRDL
QASTHLETLLTFSALNRHFKLYLTSSTERFSQNFKVVVVDGEDESEYPVKWQDFFSGHVV
GEPDSRVLAHIGDDDITVRINTDGAEYNIEPLWRLINDTKDKRVLVYKSEDIKNVSRLQS
PKVCGYIKADNEELLPKGLVDREPPDELVHRVKRRADPNPLRNTCKLLVVADHRFYKYMG
RGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGERHYNM
AKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANS
HGGVCPKAYYSPIGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGL
AECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGN
SRVDEGEECDPGIMYLNNDTCCNSDCTLRPGVQCSDRNSPCCKNCQFETAQKKCQEAINA
TCKGVSYCTGNSSECPPPGNAEDDTVCLDLGRCKDGKCVPFCEREQRLESCACNETDHSC
KVCCRAPSGRCLPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWEFIDKLS
INTFGKFLADNIVGSVLVFSLMLWIPVSILVHCVDKKLDKQYESLSLLHPSNVEMLSSMD
SASVRIIKPFPAPQTPGRLQPLQPLQPGPVLPSAPSVPVAPKLDHQRMDTIQEDPSTDSH
VDEDGFEKDPFPNSSAAAKSFEDLTDHPVTRSEKASSFKLQRQSRVDSKETEC
NT seq 2502 nt   +upstreamnt  +downstreamnt
atgaggcagtgtgcgctcttcctgaccagcttggttcctatcgtgctggcgccgcgaccg
ccggacgagccgggcttcggctcccctcagcgactcgaaaagcttgattctctgctctca
gactacgacatcctctctttatccagcattcgccagcactccgtaaggaaaagggatctg
caggcctcaacacacctagagacactactaactttttcagccttgaacaggcattttaaa
ttatacctgacatcaagtactgaacgcttctcccagaatttcaaagtcgtggtggtcgat
ggggaagatgaaagtgagtaccccgtcaagtggcaggacttcttcagtggacacgtggtt
ggtgaacctgactctagggttctcgcccacataggagatgatgatattacagtaagaatc
aacacagatggggcagaatataatatagagccactttggagactaattaatgatactaaa
gacaaaagagtgttagtttataagtctgaagatatcaagaatgtttcacgtttgcagtct
ccaaaagtgtgtggttatataaaggcggataatgaagagttgcttcctaaagggctagta
gacagagagccgcctgatgagcttgttcaccgggtgaagagaagagccgaccccaatccc
ctgaggaacacgtgtaaattattggtggtggcagatcatcgcttttataagtacatgggc
agaggggaagagagcacgaccacaaactacctgatagagctaattgacagagttgatgac
atctatcggaacacttcatgggacaatgcaggttttaaaggttatggaatacagatagag
cagattcgcattctcaagtctccacaagaggtaaaacctggtgaaaggcactacaatatg
gcaaaaagttacccaaatgaagaaaaggatgcttgggatgtgaagatgttgctagagcaa
tttagctttgatatagctgaagaagcatctaaagtctgcctggcacatcttttcacctac
caagattttgatatgggaactcttggattagcttatgttggttctcccagagcaaacagt
catggaggtgtttgtccaaaggcttattatagtccaattggaaagaaaaatatctattta
aatagtggtttgaccagcacaaaaaattatggtaaaaccatccttacaaaggaagctgac
cttgtgacaactcatgaattggggcacaattttggagcagaacacgatccagatggttta
gcagaatgtgccccaaacgaggaccagggaggaaaatacgtcatgtatcccatagccgtg
agtggtgatcatgagaacaacaagatgttttcaaactgcagtaaacagtccatctataag
accattgaaagtaaggcccaggagtgttttcaagagcgcagcaacaaagtgtgtggcaac
tccagggtggatgagggggaggagtgcgaccccggcatcatgtacctgaacaacgacacc
tgctgcaacagcgactgcaccctgaggccgggcgtccagtgcagtgataggaacagtcct
tgctgtaaaaactgtcagttcgagacggcccagaagaagtgccaggaggctattaatgcc
acttgcaaaggcgtgtcttactgcacaggtaacagcagtgagtgcccccctccgggaaac
gccgaggacgacacggtgtgcctggacctgggcaggtgcaaggacggcaagtgcgtgccc
ttctgcgagcgggagcagcggctggagtcctgcgcgtgtaacgaaaccgaccactcgtgc
aaggtgtgctgccgggccccctcgggccgttgcctgccctacgtggacgccgaacagaag
aacttgtttttgaggaaggggaagccctgtacagtaggattttgtgacatgaatggcaag
tgtgagaagcgagtgcaggacgtcatcgagcggttctgggagttcattgacaagctgagc
atcaatactttcgggaagttcctggcagacaacatcgtgggctccgtcctggtgttctcc
ctgatgctctggatccccgtcagcatcctcgtccactgcgtggataagaagctggataag
cagtacgaatccctgtctctgctgcaccccagcaacgtggagatgctaagcagcatggat
tcagcatccgttcgcatcatcaagccctttcctgcgccccagaccccaggccgcctgcag
cccctgcagcccctgcagcccggccccgtgctgccctctgcgccttcggtgcccgtggct
ccaaaactggaccaccagcggatggacaccatccaggaggaccccagcacggactcgcac
gtggacgaggacggcttcgagaaggaccctttccccaacagcagtgccgctgccaagtca
tttgaggatctcacggaccatccggtcacgagaagtgaaaaggcctcgtcctttaagctg
cagcgccagagtcgcgttgacagcaaggaaacggagtgctag

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (22)   
   KEGG ORTHOLOGY (1)   
   RefGene (17)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (7)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (4)   
DNA sequence (14)   
   RefSeq(nuc) (4)   
   GenBank (5)   
   EMBL (5)   
Protein domain (8)   
   Pfam (8)   
All databases (61)   

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