KEGG   Spirochaeta thermophila DSM 6192: STHERM_c08940
Entry
STHERM_c08940     CDS       T01315                                 
Name
(GenBank) hypothetical protein
  KO
K01929  UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10]
Organism
sta  Spirochaeta thermophila DSM 6192
Pathway
sta00300  Lysine biosynthesis
sta00550  Peptidoglycan biosynthesis
sta01100  Metabolic pathways
sta01502  Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:sta00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00300 Lysine biosynthesis
    STHERM_c08940
  09107 Glycan biosynthesis and metabolism
   00550 Peptidoglycan biosynthesis
    STHERM_c08940
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01502 Vancomycin resistance
    STHERM_c08940
Enzymes [BR:sta01000]
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.2  Acid-D-amino-acid ligases (peptide synthases)
    6.3.2.10  UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
     STHERM_c08940
SSDB
Motif
Pfam: Mur_ligase_M Mur_ligase_C Mur_ligase
Other DBs
NCBI-ProteinID: ADN01841
UniProt: E0RS54
Position
985261..986673
AA seq 470 aa
MSARTLPALSLDQLASIVGARLVAPSGERPPIRRVTIDSRECEEGVLFVPLRGRFTDGHL
YLGEAFQRGASAALVQETVFSEAGSALLKHVVQTRGALLVVTDTLEALQTLGEWYLSSLR
VPIRIGVTGSSGKTSTKEMLRAVLSLHYSRVWATEGNLNSEIGVPLSILGIREEPEVVIC
EMGIDHVGEMDVLARIVKPNLAVVTGIGSAHLERFGTRERIAREKAKIFSSFDDRSVGFI
PEDEEFFHVLVEGWRGTFLPYGPATVEGFEGWESRGLEGVILSWKGLRIPLQGYGEHMVR
NALGVIRLSGHLGVPPSMVAEGLQAYRPLFGRGELKEIGGVWFLVDCYNANPESMRASLE
GVRGLKGIRRRIVVLGSMRELGDAAPSEHRRLGDYLAGYPADVVLLVGEEMEAAFAVLEG
RSGVWWMRTVEEASSLLVSIVQEGDLVLLKGSRALGLERIIQDFEGRYHA
NT seq 1413 nt   +upstreamnt  +downstreamnt
atgagcgcccgtacccttcccgccctctccctggaccagctggcttccatcgtaggagct
cgcctcgtcgccccatccggagaacgccccccgatccggagggtcacgatcgattcccgg
gagtgtgaagaaggcgtgctcttcgtcccactcagaggtcgtttcaccgatggtcacctc
tacctgggagaggccttccaacgaggtgcgtctgcagccctggtgcaggagaccgtgttc
tctgaagcgggatcggccctcctgaaacacgtggtccagacccgcggggccctcctcgtg
gtgaccgatacgctcgaggcccttcagaccctgggcgagtggtacctttcgtccctccgg
gttccgattcggataggggtgaccgggagcagcgggaagacgtccaccaaggagatgctc
agagccgtgctctccctccactattcgagggtgtgggccaccgaagggaacctcaattcg
gaaataggcgtgccgctctcgatcctcggtatccgggaggagcctgaggtggtgatctgc
gagatgggtatcgatcatgtcggggagatggacgtgctcgcgcgtatcgtgaagcccaat
ctcgcggtcgtcacggggatagggagtgcgcatctggagcggttcggcacgagggagcgc
atcgcacgcgagaaggcgaagatcttctcctctttcgacgatcgctcggtgggcttcatc
cccgaggacgaggagttcttccatgtcctggtggaggggtggcgtggaaccttcctcccc
tacggacctgccacggtggagggcttcgaggggtgggagagtcgggggctcgaaggcgtg
atcctttcgtggaaggggctgcgtataccgctccagggatacggggaacacatggtgagg
aatgccctgggggttatccgtctctccggtcacctgggtgttcctccctcgatggtggcg
gaggggctccaggcctaccgtccgctcttcgggagaggggagctcaaggagatcgggggg
gtgtggttcctcgtggattgttacaatgcgaatcccgagtccatgagggcttcgctcgag
ggcgtgcggggtctcaaggggatccggaggcgcatcgtggtcctcgggagcatgcgtgag
ctgggggatgccgctccgtccgagcacaggaggctgggggactatctcgccggatatccg
gcggatgtggtgctgctggtgggtgaggagatggaagccgcctttgctgtactcgagggg
cggagcggggtctggtggatgaggaccgtggaggaagcgtcctcgctcctcgtttcgatc
gttcaggaaggggatctcgtactgctcaaaggctcgagggcactgggcctggaacggatc
atccaggacttcgaggggaggtatcatgcttaa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical substance (8)   
   KEGG COMPOUND (8)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (11)   
   KEGG ORTHOLOGY (1)   
   RefGene (8)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (3)   
   Pfam (3)   
All databases (33)   

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