KEGG   Streptomyces sp. SAT1: A8713_22105
Entry
A8713_22105       CDS       T04706                                 
Name
(GenBank) 2-isopropylmalate synthase
  KO
K01649  2-isopropylmalate synthase [EC:2.3.3.13]
Organism
strt  Streptomyces sp. SAT1
Pathway
strt00290  Valine, leucine and isoleucine biosynthesis
strt00620  Pyruvate metabolism
strt01100  Metabolic pathways
strt01110  Biosynthesis of secondary metabolites
strt01210  2-Oxocarboxylic acid metabolism
strt01230  Biosynthesis of amino acids
Module
strt_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:strt00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    A8713_22105
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    A8713_22105
Enzymes [BR:strt01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.3  Acyl groups converted into alkyl groups on transfer
    2.3.3.13  2-isopropylmalate synthase
     A8713_22105
SSDB
Motif
Pfam: HMGL-like LeuA_dimer
Other DBs
NCBI-ProteinID: ANH93521
UniProt: A0A1A9J106
Position
complement(5099813..5101600)
AA seq 595 aa
MTTTPSTTTAHPTAPYGRPLWNPQRPGPMPYHRYRPFQERVRVPVPAEGRGWPSARIERA
PLWVPVDLRDGNQALAEPMDTPRKRRFFDLLVRLGFKEIEVGYPSASRTDFDFVRHLVTS
GAVPDDVTPVVFTPARRDLIDRTFEAVAGLPRAVVHLYMATSPVWREVVLGRDRDGVRAS
VRDAAAHMARRADALPGGAHLRFQFSPETFNLTEPDYVLELCDGLTELWDASPDRPVTHN
LPATVEIATPNVYADQIEYVHRHLSRRDAVILSVHPHNDRGTGVACAELAVLAGAQRVEG
CLFGNGERTGNVDLVTLALNLYAQGVDPMVDFSDIDAVRATVEHCNRLPVHPRHPYAGDL
VHTAFSGTHQDAISKGLDAHARRAAETGTAPELAPWSVPYLPIDPADVGRSYEAVIRVNS
QSGKGGVAYLLRAHASLDLPRRMRPEVSRAVQEATDGSGREATPKELYELFRTTYLAVDG
PVRLDAWSVHREPSGAHRFVCSLGHGDRTGDHEGTGDGPVSAFVDALAGAGLAVAVLDFA
EHRSAAPGEEGGAEVTTAYAECRVNGTTAWGAGRDASSLTAAVHAVLAAVNRAAR
NT seq 1788 nt   +upstreamnt  +downstreamnt
atgaccaccaccccgagcaccaccaccgcgcaccccaccgccccgtacgggagaccgctg
tggaatccgcagcgtcccgggcccatgccctaccaccgctaccgccccttccaggagcgg
gtgcgcgtgcccgtcccggcagagggccgcggctggccgtccgcccggatcgagcgcgcg
ccgctgtgggtcccggtcgacctgcgcgacggcaaccaggcgctggccgagccgatggac
accccgcgcaagcgccgcttcttcgatctgctggtgcggctggggttcaaggagatcgag
gtcggctacccgtcggcgagccgcaccgacttcgacttcgtccggcacctggtgaccagc
ggggccgtgcccgacgacgtcacgccggtcgtcttcaccccggcccgccgggacctgatc
gaccgcaccttcgaggcggtggcggggctgccgcgggccgtcgtccacctgtacatggcg
acctcgcccgtctggcgcgaggtggtgctcgggcgggaccgggacggggtgcgcgcgagc
gtacgggacgcggcggcgcacatggcccggcgcgcggacgccctgcccggcggcgcgcac
ctccgcttccagttctccccggagaccttcaacctcaccgagccggactacgtcctcgaa
ctgtgcgacgggctcaccgagctgtgggacgcgagcccggaccggccggtcacgcacaac
ctccccgccacggtggagatcgccaccccgaacgtctacgcggaccagatcgagtacgtg
caccgccatctgtcccgccgggacgcggtgatcctctcggtgcacccgcacaacgaccgc
ggcaccggcgtcgcctgcgccgaactcgccgtgctggcgggcgcgcagcgggtcgaaggc
tgcctgttcggcaacggcgagcgcaccgggaacgtggacctggtgaccctggcgctcaat
ctgtacgcgcagggcgtcgacccgatggtcgacttcagcgacatcgacgcggtacgggcg
acggtggagcactgcaaccggctgccggtgcatccgcgccacccctacgcgggcgacctc
gtccacaccgcgttctccggcacccaccaggacgcgatcagcaagggcctggacgcgcac
gcccggcgtgccgccgagacgggcaccgcgccggagctggcgccgtggtcggtgccgtat
ctgccgatcgatccggccgacgtgggccggtcctacgaggcggtgatccgggtcaactcc
cagtcgggcaagggcggggtggcgtatctgctgcgcgcgcacgcgagtctggacctgccg
cggcggatgcggccggaggtgtcgcgggcggtccaggaggccacggacggcagcgggcgt
gaggcgacgccgaaggagctgtacgagctgttccgcacgacgtacctggcggtggacggg
ccggtgcggctggacgcctggtcggtgcaccgggagccgtccggggcgcaccgcttcgtc
tgctcgctgggccacggcgaccgcaccggcgaccacgagggcaccggggacggaccggtg
agcgccttcgtggacgcgctcgccggggccggactcgccgtggccgtgctcgacttcgcc
gagcaccggtcggcggcgcccggcgaggagggcggcgccgaggtgacgaccgcgtacgcc
gagtgccgggtgaacggcacgacggcctggggcgccggccgggacgcctcgtcgctgacg
gccgccgtgcacgcggtgctggccgccgtgaaccgggccgcgcgatga

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