KEGG   Thermus brockianus: A0O31_02000
Entry
A0O31_02000       CDS       T04600                                 
Name
(GenBank) 2-isopropylmalate synthase
  KO
K01649  2-isopropylmalate synthase [EC:2.3.3.13]
Organism
tbc  Thermus brockianus
Pathway
tbc00290  Valine, leucine and isoleucine biosynthesis
tbc00620  Pyruvate metabolism
tbc01100  Metabolic pathways
tbc01110  Biosynthesis of secondary metabolites
tbc01210  2-Oxocarboxylic acid metabolism
tbc01230  Biosynthesis of amino acids
Module
tbc_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:tbc00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    A0O31_02000
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    A0O31_02000
Enzymes [BR:tbc01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.3  Acyl groups converted into alkyl groups on transfer
    2.3.3.13  2-isopropylmalate synthase
     A0O31_02000
SSDB
Motif
Pfam: HMGL-like LeuA_dimer TipAS
Other DBs
NCBI-ProteinID: APD10072
UniProt: A0A1J0LV36
Position
1809967..1811523
AA seq 518 aa
MERHIRIFDTTLRDGEQSPGVALSLDQKLEIAHALARLNVDIIEAGFPVSGPLEFEAVRR
IATEVKGPIIAALARTHTLDIDQAAKALEKAEKPRIHVFTSASKIHLEYMLKKTEEEVLE
MADQMVRYARRYVDDVEFSAQDVMRADWDFVKRLYEVAIEAGATTINIPDTTGYGTPGEY
GALIRRIRDEVVRGRDVIISTHTHDDLGLAVANALAGVENGAGQVECTINGIGERAGNTS
LEEVVMALYVRRDWYKAYTQINTREIYRVSRLVERYTGMPVPPNKAIVGDNAFAHESGIH
QDGVLKHRATYEIMDAELIGRRPAVIVLGKHSGRAAFRKALEDLGYKDLSEEELKKLFAR
FKEIAEKKGPLSAEELQALVESEREPASHFFTLEHVQFFSGSGLLPTATVKVRTPEGERV
ATHTGDGPVDAVYKAIQEAIGLRPELELYRVEAITGSTEALGQVTVRLRLGELQAVGVGV
SPDIIEASALAFLDAAGKLVSGRATRHPPSIAEVQRGV
NT seq 1557 nt   +upstreamnt  +downstreamnt
atggagcggcacatccgaatctttgacaccacgcttagggacggcgagcagagcccaggg
gtggcgctttccttggaccagaagctggaaatcgcccatgccctggcccggctcaacgtg
gacatcattgaggcgggctttcccgtatccgggcctttggagtttgaggcggtgcggcgc
atcgccacggaggtaaagggccccatcatcgccgccttggcccgcacccacaccctggac
attgaccaggcggccaaggccttggagaaggcggaaaagccaaggattcacgtcttcacc
tccgcctccaagatccacctggagtacatgctgaagaagacggaggaggaggtcttggag
atggcggaccaaatggtccgctacgcccgccgctacgtggacgacgtggagttttccgcc
caggacgtgatgcgggcggactgggacttcgtgaagcggctttacgaggtggccatagag
gcgggggccaccaccatcaacatccccgacaccacgggctacggcacgcctggggagtac
ggggccctcatccgccgcatccgcgacgaggtggtgcgggggcgggatgtcatcatctcc
acccacacccacgacgacctgggcctcgccgtggccaacgccctggccggcgtggagaac
ggggcggggcaggtggagtgcaccatcaacggcattggggagcgggcggggaacacctcc
ttggaggaggtggtcatggcgctctacgtgcgccgggactggtacaaggcctacacccag
atcaacacccgggagatctaccgggtttcccgcctggtggagcgctacacggggatgccc
gtcccccccaacaaggccatcgtgggggacaacgccttcgcccacgagtccggcatccac
caggacggcgtcctgaagcaccgggccacctacgagatcatggacgccgagctcatcggc
cgccggcccgcggtgatcgtcctgggcaagcactcggggcgggcagccttcaggaaggcc
ctggaggatctgggctacaaggacctctccgaggaggagctgaagaagctcttcgcccgc
ttcaaggagatcgccgagaaaaagggtcccctttccgccgaggagctccaggccctggtg
gaaagcgagcgcgagcccgcctcccacttcttcaccctggaacacgttcagttcttctcg
ggctcgggcctcttgcccacggccacggtgaaggtgaggacccccgagggggagcgggtg
gccacccacacaggggatgggccggtggacgccgtgtacaaggccatccaggaggccatc
ggtctcaggcccgagctggagctctaccgggtggaggccatcacggggagcaccgaggcc
ttgggccaggtgacggtgcggctccggctgggtgagctccaggcggtgggggtgggggtt
tccccggacatcattgaggccagcgccttggccttcttggacgccgccgggaagctggtc
tcgggccgggccacccggcatcccccttccatcgccgaggtccagcgcggggtctag

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (7)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (3)   
   Pfam (3)   
All databases (24)   

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