KEGG   Thermosipho melanesiensis: Tmel_0486
Entry
Tmel_0486         CDS       T00550                                 
Name
(GenBank) D-alanine--D-alanine ligase
  KO
K01921  D-alanine-D-alanine ligase [EC:6.3.2.4]
Organism
tme  Thermosipho melanesiensis
Pathway
tme00470  D-Amino acid metabolism
tme00550  Peptidoglycan biosynthesis
tme01100  Metabolic pathways
tme01502  Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:tme00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00470 D-Amino acid metabolism
    Tmel_0486
  09107 Glycan biosynthesis and metabolism
   00550 Peptidoglycan biosynthesis
    Tmel_0486
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01502 Vancomycin resistance
    Tmel_0486
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01011 Peptidoglycan biosynthesis and degradation proteins [BR:tme01011]
    Tmel_0486
Enzymes [BR:tme01000]
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.2  Acid-D-amino-acid ligases (peptide synthases)
    6.3.2.4  D-alanine---D-alanine ligase
     Tmel_0486
Peptidoglycan biosynthesis and degradation proteins [BR:tme01011]
 Precursor biosynthesis
  Amino acid ligase
   Tmel_0486
SSDB
Motif
Pfam: Dala_Dala_lig_C Dala_Dala_lig_N ATP-grasp ATP-grasp_3 ATP-grasp_4 CPSase_L_D2
Other DBs
NCBI-ProteinID: ABR30353
UniProt: A6LKA2
Position
511969..513054
AA seq 361 aa
MLNIGIFFGSKSVEHEISIITAQQVLSSIDRKKYNVIPIYISKSGEWFTGKVLEDLETFK
DFDKLEKKAKKIDSFSVKNNKLLLKYGLKKQTIDFCFLVFHGTNGEDGTFQGMCEIFGIP
YSGCNHFSSAFTMDKVVTKLLLKEKEISVVDFEYTTEINEEFFKRCEKNLGYPMIVKPAR
LGSSIGVSKVVDRKNFEEAVKNVLLFDNKVLVEKWINAREINCAVMGYKNIFVSELEEIN
KKNDFFNFEEKYFKKGKKFSNHIIPARIDENLKNKIKEIAKDTFKILECSGNVRIDFLIA
DKIYVNEINTIPGALSFYIWQKSGFTFSQIIDNMINMGLERFKDKKIVSIDTNILKIKVG
K
NT seq 1086 nt   +upstreamnt  +downstreamnt
atgctaaatatcggtatattttttggctcaaaaagtgtagaacacgaaatatccataata
actgcacagcaagtactttcttccattgataggaaaaaatacaatgttatccctatttat
atatccaaatctggcgaatggtttacaggaaaagttttagaagatttagaaacttttaaa
gattttgataagttagaaaaaaaagcaaaaaaaatagatagtttcagtgtaaagaataac
aaacttcttctaaaatatggactaaaaaagcaaacgatagatttctgctttttagttttt
catggcacaaacggtgaagatggaacttttcagggaatgtgtgaaatttttgggatacca
tactctggttgtaatcatttttcatcagcttttactatggataaggtagtaacaaaactt
ttgttgaaggagaaagaaatttcagttgtagattttgaatacacaacagaaataaatgaa
gaattttttaaaagatgcgagaaaaatttaggctatcctatgattgtaaaacctgcaaga
cttggttcaagtataggtgtatcaaaagtggtagatagaaaaaatttcgaagaagcagta
aaaaatgtactcttattcgataacaaagtattagttgaaaaatggataaacgcacgtgaa
atcaattgtgccgtcatgggatacaaaaatatctttgtttctgaacttgaagaaataaac
aagaaaaacgacttttttaactttgaagaaaaatactttaaaaaaggaaaaaaattctca
aatcacattattcctgctagaatagatgaaaatttaaaaaataagataaaagaaattgca
aaagacacgtttaaaattctagaatgctctggaaacgtacgcatagatttcttgatagca
gataaaatatacgttaacgaaataaacactatacctggtgctttatcattttacatatgg
cagaagagtggatttacattttcgcagataattgataacatgataaacatgggactagaa
agattcaaagacaaaaagatagtttcaatagataccaatattttgaaaataaaggtgggc
aaatga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (24)   
   KEGG ORTHOLOGY (1)   
   RefGene (21)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   SWISS-PROT (1)   
Protein domain (6)   
   Pfam (6)   
All databases (47)   

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