ID A0A060HI65_9ARCH Unreviewed; 652 AA.
AC A0A060HI65;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 24-JAN-2024, entry version 28.
DE RecName: Full=acetate--CoA ligase {ECO:0000256|ARBA:ARBA00013275};
DE EC=6.2.1.1 {ECO:0000256|ARBA:ARBA00013275};
GN Name=acsA1 {ECO:0000313|EMBL:AIC15238.1};
GN ORFNames=NVIE_010120 {ECO:0000313|EMBL:AIC15238.1};
OS Nitrososphaera viennensis EN76.
OC Archaea; Nitrososphaerota; Nitrososphaeria; Nitrososphaerales;
OC Nitrososphaeraceae; Nitrososphaera.
OX NCBI_TaxID=926571 {ECO:0000313|EMBL:AIC15238.1, ECO:0000313|Proteomes:UP000027093};
RN [1] {ECO:0000313|EMBL:AIC15238.1, ECO:0000313|Proteomes:UP000027093}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=EN76 {ECO:0000313|EMBL:AIC15238.1};
RX PubMed=24907263; DOI=10.1099/ijs.0.063172-0;
RA Stieglmeier M., Klingl A., Alves R.J., Rittmann S.K., Melcher M.,
RA Leisch N., Schleper C.;
RT "Nitrososphaera viennensis gen. nov., sp. nov., an aerobic and mesophilic,
RT ammonia-oxidizing archaeon from soil and a member of the archaeal phylum
RT Thaumarchaeota.";
RL Int. J. Syst. Evol. Microbiol. 64:2738-2752(2014).
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DR EMBL; CP007536; AIC15238.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A060HI65; -.
DR STRING; 926571.NVIE_010120; -.
DR KEGG; nvn:NVIE_010120; -.
DR HOGENOM; CLU_000022_3_6_2; -.
DR Proteomes; UP000027093; Chromosome.
DR GO; GO:0003987; F:acetate-CoA ligase activity; IEA:UniProtKB-EC.
DR GO; GO:0016208; F:AMP binding; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0019427; P:acetyl-CoA biosynthetic process from acetate; IEA:InterPro.
DR CDD; cd05966; ACS; 1.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR011904; Ac_CoA_lig.
DR InterPro; IPR032387; ACAS_N.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR NCBIfam; TIGR02188; Ac_CoA_lig_AcsA; 1.
DR PANTHER; PTHR24095; ACETYL-COENZYME A SYNTHETASE; 1.
DR PANTHER; PTHR24095:SF14; ACETYL-COENZYME A SYNTHETASE 1; 1.
DR Pfam; PF16177; ACAS_N; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000313|EMBL:AIC15238.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000027093}.
FT DOMAIN 31..83
FT /note="Acetyl-coenzyme A synthetase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16177"
FT DOMAIN 90..471
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 532..610
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 652 AA; 72559 MW; BE8053B50400D072 CRC64;
MMYIYLSGPP SKLYEESSEV KVTVRPGMAL EDMSKEALSD PEKFWAEQAR GLDWHRQWDR
VLDWNPPFAR WFSGGLLNAS VNCLDRHVTT ETKNKAAIIW ESESGESRTL TYFQLYRYVN
RFANVLKGLG VQKGDRVTIY MPMVPELPVA MLACARIGAT HSVVFSGFSS QALVDRVNDA
QSKVIVTADG GFRKGKLVDL KRVVDESLAQ TPSVQHVVVF RRAGNDVRMG PKDVWWHEAI
EKAPMFCPPE MVESTHPLYI LYTSGTTGKP KGVMHGTAGY LVHLYATAKW VFDFNKSDIF
FCTADIGWVT GHSYIVYAPL MHGITEIMYD GAPDYPRPDR YWAVAEKHGA TILYTTPTAL
RMYMKYGDAI PNSFDLSFLR LLGTVGEPIN PEVWQWYFTT IGKERCPIID TWWQTETGGI
MLSACTGVDF VPMKPGSATF PVPGVDAVVV DDSGSPVPPG TKGYLVVRKP WPGMLLSLWG
DDEKYRKTYW SKFEGVYYPG DYALVDKDGY LWLLGRADDV LKVAGHRLGT MELESAFVAH
KAIAEAAVAS RPDSTKGESI IAFLVAKEGV AASDALRKDI VEHIRKTVGP IATPDEVYFV
GKLPKTRSGK IMRRLLKAIA SGDKIGDITT LEDGAAIDEV RHAYDELKKA VG
//
