ID A0A067CXD4_SAPPC Unreviewed; 612 AA.
AC A0A067CXD4;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=Purple acid phosphatase {ECO:0000256|RuleBase:RU361203};
DE EC=3.1.3.2 {ECO:0000256|RuleBase:RU361203};
GN ORFNames=SPRG_01804 {ECO:0000313|EMBL:KDO33925.1};
OS Saprolegnia parasitica (strain CBS 223.65).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Saprolegniales; Saprolegniaceae;
OC Saprolegnia.
OX NCBI_TaxID=695850 {ECO:0000313|EMBL:KDO33925.1, ECO:0000313|Proteomes:UP000030745};
RN [1] {ECO:0000313|EMBL:KDO33925.1, ECO:0000313|Proteomes:UP000030745}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 223.65 {ECO:0000313|EMBL:KDO33925.1,
RC ECO:0000313|Proteomes:UP000030745};
RX PubMed=23785293;
RA Jiang R.H., de Bruijn I., Haas B.J., Belmonte R., Lobach L., Christie J.,
RA van den Ackerveken G., Bottin A., Bulone V., Diaz-Moreno S.M., Dumas B.,
RA Fan L., Gaulin E., Govers F., Grenville-Briggs L.J., Horner N.R.,
RA Levin J.Z., Mammella M., Meijer H.J., Morris P., Nusbaum C., Oome S.,
RA Phillips A.J., van Rooyen D., Rzeszutek E., Saraiva M., Secombes C.J.,
RA Seidl M.F., Snel B., Stassen J.H., Sykes S., Tripathy S., van den Berg H.,
RA Vega-Arreguin J.C., Wawra S., Young S.K., Zeng Q., Dieguez-Uribeondo J.,
RA Russ C., Tyler B.M., van West P.;
RT "Distinctive expansion of potential virulence genes in the genome of the
RT oomycete fish pathogen Saprolegnia parasitica.";
RL PLoS Genet. 9:E1003272-E1003272(2013).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a phosphate monoester + H2O = an alcohol + phosphate;
CC Xref=Rhea:RHEA:15017, ChEBI:CHEBI:15377, ChEBI:CHEBI:30879,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:67140; EC=3.1.3.2;
CC Evidence={ECO:0000256|RuleBase:RU361203};
CC -!- SIMILARITY: Belongs to the metallophosphoesterase superfamily. Purple
CC acid phosphatase family. {ECO:0000256|RuleBase:RU361203}.
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DR EMBL; KK583192; KDO33925.1; -; Genomic_DNA.
DR RefSeq; XP_012195559.1; XM_012340169.1.
DR AlphaFoldDB; A0A067CXD4; -.
DR EnsemblProtists; KDO33925; KDO33925; SPRG_01804.
DR GeneID; 24124384; -.
DR KEGG; spar:SPRG_01804; -.
DR VEuPathDB; FungiDB:SPRG_01804; -.
DR OMA; SVQWMTK; -.
DR OrthoDB; 203742at2759; -.
DR Proteomes; UP000030745; Unassembled WGS sequence.
DR GO; GO:0003993; F:acid phosphatase activity; IEA:UniProtKB-EC.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR CDD; cd00839; MPP_PAPs; 1.
DR Gene3D; 3.60.21.10; -; 1.
DR Gene3D; 2.60.40.380; Purple acid phosphatase-like, N-terminal; 1.
DR InterPro; IPR004843; Calcineurin-like_PHP_ApaH.
DR InterPro; IPR029052; Metallo-depent_PP-like.
DR InterPro; IPR041792; MPP_PAP.
DR InterPro; IPR008963; Purple_acid_Pase-like_N.
DR InterPro; IPR015914; Purple_acid_Pase_N.
DR InterPro; IPR025733; Purple_acid_PPase_C_dom.
DR PANTHER; PTHR45867:SF3; ACID PHOSPHATASE TYPE 7; 1.
DR PANTHER; PTHR45867; PURPLE ACID PHOSPHATASE; 1.
DR Pfam; PF00149; Metallophos; 1.
DR Pfam; PF14008; Metallophos_C; 1.
DR Pfam; PF16656; Pur_ac_phosph_N; 1.
DR SUPFAM; SSF56300; Metallo-dependent phosphatases; 1.
DR SUPFAM; SSF49363; Purple acid phosphatase, N-terminal domain; 1.
PE 3: Inferred from homology;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Hydrolase {ECO:0000256|RuleBase:RU361203};
KW Reference proteome {ECO:0000313|Proteomes:UP000030745};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT DOMAIN 195..286
FT /note="Purple acid phosphatase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16656"
FT DOMAIN 297..504
FT /note="Calcineurin-like phosphoesterase"
FT /evidence="ECO:0000259|Pfam:PF00149"
FT DOMAIN 524..579
FT /note="Iron/zinc purple acid phosphatase-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF14008"
SQ SEQUENCE 612 AA; 67816 MW; B36336227680D5D1 CRC64;
MASLRHRVGV ALGALTLLFL LVVRDVVERR ALLVPLRYLQ HPLNPVVLSP DELDDESDTD
DVDGTPFLPG WIENCVPYDI VSTVDAAGNA SITWRTHRMY KSSNENDDGW VECGAGKGHV
QFRPVGQGQL YSSIYSEADR DADGNITTHV VSFSVPDPAA AYEFIVGSHH HGYSSRHRLG
HNVDYSLSHG FACRPTRIHA AYGASPSTFT IQWATPPECT NGRHVLVVRA DIDDGEAPRT
FVADSIVFGA RYEHVAAAVQ LRSNTRYAYY VGNDAYSRSI LYSFTTPRGV DDAPAPLRLL
VTGDIGYQNA ATLPMMQSEV ARGDIDAVIS VGDYAYNLHS AGGVVGDIFM TEIEPIAATV
PFMVAMGNHE VKQHFSHYTY RFQLMPANAG TVSIQGQQLR NNWFYSYNVG LVHFVVVNTE
VYFTSHVDEP NVEARQRAWL DADLATANAN RTAAPWIIVV GHRPLYCTSD TECDGPARVL
RTALEPLFYN HGVDLYLCGH QHNYERMFDI YDGITERRTR NMQATTHILT GAAGQSRVLP
VRKPFLRTAA PWDAFRNNIF GYGRLTIANA SHLHWAQIEC DPANPAASHL NGKAVDDVWL
VQERHGSFAN LT
//
