ID A0A067KCX7_JATCU Unreviewed; 2200 AA.
AC A0A067KCX7;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE RecName: Full=Histone-lysine N-methyltransferase {ECO:0008006|Google:ProtNLM};
GN ORFNames=JCGZ_12155 {ECO:0000313|EMBL:KDP32863.1};
OS Jatropha curcas (Barbados nut).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Malpighiales; Euphorbiaceae; Crotonoideae; Jatropheae;
OC Jatropha.
OX NCBI_TaxID=180498 {ECO:0000313|EMBL:KDP32863.1, ECO:0000313|Proteomes:UP000027138};
RN [1] {ECO:0000313|EMBL:KDP32863.1, ECO:0000313|Proteomes:UP000027138}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. GZQX0401 {ECO:0000313|Proteomes:UP000027138};
RC TISSUE=Young leaves {ECO:0000313|EMBL:KDP32863.1};
RX PubMed=24837971; DOI=10.1371/journal.pone.0097878;
RA Zhang L., Zhang C., Wu P., Chen Y., Li M., Jiang H., Wu G.;
RT "Global Analysis of Gene Expression Profiles in Physic Nut (Jatropha curcas
RT L.) Seedlings Exposed to Salt Stress.";
RL PLoS ONE 9:E97878-E97878(2014).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KK914570; KDP32863.1; -; Genomic_DNA.
DR RefSeq; XP_012078323.1; XM_012222933.1.
DR STRING; 180498.A0A067KCX7; -.
DR GeneID; 105639000; -.
DR KEGG; jcu:105639000; -.
DR OrthoDB; 54704at2759; -.
DR Proteomes; UP000027138; Unassembled WGS sequence.
DR GO; GO:0005694; C:chromosome; IEA:UniProtKB-KW.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0046975; F:histone H3K36 methyltransferase activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd19172; SET_SETD2; 1.
DR Gene3D; 3.30.40.100; -; 1.
DR Gene3D; 2.170.270.10; SET domain; 1.
DR InterPro; IPR006560; AWS_dom.
DR InterPro; IPR003616; Post-SET_dom.
DR InterPro; IPR001214; SET_dom.
DR InterPro; IPR046341; SET_dom_sf.
DR InterPro; IPR044437; SETD2/Set2_SET.
DR InterPro; IPR011124; Znf_CW.
DR PANTHER; PTHR22884:SF413; HISTONE-LYSINE N-METHYLTRANSFERASE CG1716-RELATED; 1.
DR PANTHER; PTHR22884; SET DOMAIN PROTEINS; 1.
DR Pfam; PF17907; AWS; 1.
DR Pfam; PF00856; SET; 1.
DR Pfam; PF07496; zf-CW; 1.
DR SMART; SM00570; AWS; 1.
DR SMART; SM00508; PostSET; 1.
DR SMART; SM00317; SET; 1.
DR SUPFAM; SSF82199; SET domain; 1.
DR PROSITE; PS51215; AWS; 1.
DR PROSITE; PS50868; POST_SET; 1.
DR PROSITE; PS50280; SET; 1.
DR PROSITE; PS51050; ZF_CW; 1.
PE 4: Predicted;
KW Chromosome {ECO:0000256|ARBA:ARBA00022454};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000027138};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 1105..1159
FT /note="CW-type"
FT /evidence="ECO:0000259|PROSITE:PS51050"
FT DOMAIN 1217..1267
FT /note="AWS"
FT /evidence="ECO:0000259|PROSITE:PS51215"
FT DOMAIN 1269..1386
FT /note="SET"
FT /evidence="ECO:0000259|PROSITE:PS50280"
FT DOMAIN 1394..1410
FT /note="Post-SET"
FT /evidence="ECO:0000259|PROSITE:PS50868"
FT REGION 301..326
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 585..618
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 675..703
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 887..933
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 998..1055
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1860..1903
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2088..2110
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 301..315
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 593..615
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 679..702
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1012..1055
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2091..2110
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2200 AA; 242003 MW; DE7492E007D47032 CRC64;
MGSCENSLEV HEPLQQAYIE QHLCSIKNSD SEKLPCSEAG VDVIDNDVGP TGALDGFLEL
SQNDSAGCVS SSELRGAESV DWVIGSATEV ECGNERQSGI DDCSVETDGF CVEKEASNNE
NNGSENSLED CERSLELVHA SSSVRNCDQQ DEEKDDWNVR REMEEKTDGL AGTKIETCDQ
MMPSFNCEMP AELIAVDALA INGVEPDKDI RAILERAVVV MENKTAGLVE IDTDNHSQTG
PASNYVQLDD QKDQQLNNSP SAKVVTEVIK TNSNVSPMIE TIAHNQLFSC QGFDEALELM
PKTDSSEESI KQEEQNDDGS ITLPSEQGVM EKKSNLSTGV KCNLNNQTFS SMDDEMHVEL
DPFPLLPKHS CQQNDLEAKT VNSVGSMGVV NGKSDASATT DSDICIQKTL HHIAMPKESS
ITGSLESTCE RKNDQKNGFS VNCFTAETVS TDILKKSGVD KCIQAYPSQA CQRTLENLAI
ADSLGNPVYE PFIEGMPGIV EEESDVTTEI KFEIHGQKFC VEGDAYDLKE GSPEKTPSSA
QSCQPFGKDV SHDIYSSHSV DCSEQIDKEG KVLAGSCPSK TTCLDIGSSS SRRSKRIRKS
GQKTQTKRAA KKRKNKAKLQ DLQIFKADRR KRSCFSKPAR SSNWGLLGNI TQFFEQSNGL
GLNEIQYCGP RKIKVEQGNG KRGNSQPSGS SQKSSGKKNS STGGIRLKVI VRKEVGQNSL
NLVVPEVIDT STSGVLVSEF EAKTYTGTSS KIPNVVSGAE DKMGEREREE QLQCFGNKLE
EAKVYPNASV SDFHVADKDF EGHLICQNSA VDAAADYLGV PSHLEVDISG EATEKRYTDP
GTSPDSEVIN LVPEGQVNAT CQEDLHDVVL TSPKAFVAAG AVARGKKGKK KDRRIRVSDN
FAEDISPGMS SMKSVKTTKK HGGRQGKDDG FLSSQILISP TKANVSSNFS SHKEFSEEQL
HLSRKTEFRV SEEALQAESG LDFGPRLSES QNSNNLLHSV KSKSKGGQLP KKSDGASKRR
SKTSDKARSK KENGCGQRGS ERKTVNKNKA KEKSECDHVY KSADNPETGN CIAKDTGKTN
PVDSVASIDV ANLDMASTDA VEQQPPADNA WVRCDDCHKW RRIPVTLVDL IGQSNCQWIC
EDNMDKAFAD CSIPQEKSNA EINAELGLSD ADEDAYDAPL KNKGLEWKRT AVSKEHEFTR
ISTNQFLHRC RKTQTIDEIM VCHCKLPLHG GLGCGDECLN RMLNIECVQG TCPCGDLCSN
QQFQKRHYAK MQWARCGKKG FGLRLEEDIS KGQFLIEYVG EVLDMHTYEV RMREYASMSH
KHFYFMTLNG SEVIDACAKG NLGRFINHSC DPNCRTEKWV VNGEICIGLF ALRDIKKGEE
VTFDYNYVRV VGAAAKQCYC GSPQCRGYIG GDPTSTEVID QVDSDEEFPE PVMLEDGEAG
ERFKNRLSRI SSFDGVELQV AESISKDRNK MDISTTATEK MEVGLEIEDG MNQSVSAISQ
LSSPMEMNDS RGDIPSSSQP VEMSAQADDV ISKSASPVKQ EISKEDIQSG ETCPTAMLSK
LSSDGMVANR KSKSATAEEK RVFVKSRFLI KTSHHSGSGK KGKFTSNPTN ANKVQMVASK
SQLLSIKPKR SIDGTSNGRF EAVEEKLNEL LDADGGISKR KDAPKVYLKL LLLTAASGAS
GNGEAIQSNR DLSMILDALL KTKSRVVLID IINKNGLRML HNMIKQYRWD FKKIPILRKL
LKVLEYLAVR EILTPEHING GPPCPGMESF RESMLLLTEH NDKQVHQIAR NFRNRWIPQH
GRKYRHEDRD DGRMEFHRGS VNNRVSVPLN HSRDLGVRPT EAIECASQSK LATASSVDSA
VHEGCSAPSV GGVVKTRKRK SRWDQPAEEK PSSRSLQSDG QKIQSGLLQQ SEYHSQPEMG
KEILDNVEKG SKENSYCPHC ALNYYLQDEV SCADDGRQNM QSDVPPGFSS PLNQNLVSSS
SSSTITEIQQ QNGCMASPIG TVVGHPQEKF ISRMYVSYGI PLPIVQQFGS PRDGKVESWT
VAPGMPFHPF PPLPPFPQHK KETPSPAVNS MVINGSTEER QRDRHDLATC YPNENNPSTA
GGNQPDMDIP SENGQQAFKR ARGSSHDLGK RYFRQQKWNK VLPPWIRNRD GFGCLGNNSR
GGICTDVGSL TNDHRNSYCS QDVSCRVEKA GNCINQQKST
//
