ID A0A071KVM7_PSEAI Unreviewed; 484 AA.
AC A0A071KVM7;
DT 01-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 69.
DE RecName: Full=Trk system potassium uptake protein {ECO:0000256|PIRNR:PIRNR006247};
GN Name=trkH2 {ECO:0000313|EMBL:QJE85977.1};
GN ORFNames=GNQ48_21675 {ECO:0000313|EMBL:MUI37623.1}, IPC737_15360
GN {ECO:0000313|EMBL:RPW73511.1}, PA52Ts2_4576
GN {ECO:0000313|EMBL:QJE85977.1};
OS Pseudomonas aeruginosa.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=287 {ECO:0000313|EMBL:MUI37623.1, ECO:0000313|Proteomes:UP000433532};
RN [1] {ECO:0000313|EMBL:RPW73511.1, ECO:0000313|Proteomes:UP000284878}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CPHL10662 {ECO:0000313|EMBL:RPW73511.1,
RC ECO:0000313|Proteomes:UP000284878};
RA Feschi L., Jeukens J., Emond-Rheault J.-G., Kukavica-Ibrulj I., Boyle B.,
RA Levesque R.C.;
RL Submitted (AUG-2017) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:RPW73511.1, ECO:0000313|Proteomes:UP000284878}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CPHL10662 {ECO:0000313|EMBL:RPW73511.1,
RC ECO:0000313|Proteomes:UP000284878};
RA Freschi L., Vincent A.T., Jeukens J., Emond-Rheault J.-G.,
RA Kukavica-Ibrulj I., Dupont M.-J., Charette S.J., Boyle B., Levesque R.C.;
RT "The Pseudomonas aeruginosa pan-genome provides new insights on its
RT population structure, horizontal gene transfer and pathogenicity.";
RL Submitted (JAN-2019) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:MUI37623.1, ECO:0000313|Proteomes:UP000433532}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PA221 {ECO:0000313|EMBL:MUI37623.1,
RC ECO:0000313|Proteomes:UP000433532};
RA Khan M., Rice S.A., Willcox M.D.P., Stapleton F.;
RT "Genomes of ocular Pseudomonas aeruginosa isolates.";
RL Submitted (NOV-2019) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|EMBL:QJE85977.1, ECO:0000313|Proteomes:UP000502341}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GIMC5020:PA52Ts2 {ECO:0000313|EMBL:QJE85977.1,
RC ECO:0000313|Proteomes:UP000502341};
RA Voronina O.L., Kunda M.S., Aksenova E.I., Ryzhova N.N., Semenov A.N.;
RL Submitted (APR-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Low-affinity potassium transport system. Interacts with Trk
CC system potassium uptake protein TrkA. {ECO:0000256|PIRNR:PIRNR006247}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000256|PIRNR:PIRNR006247}; Multi-pass membrane protein
CC {ECO:0000256|PIRNR:PIRNR006247}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the TrkH potassium transport family.
CC {ECO:0000256|PIRNR:PIRNR006247}.
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DR EMBL; WOAD01000021; MUI37623.1; -; Genomic_DNA.
DR EMBL; CP051768; QJE85977.1; -; Genomic_DNA.
DR EMBL; NSTV01000005; RPW73511.1; -; Genomic_DNA.
DR RefSeq; WP_003091497.1; NZ_WXZW01000033.1.
DR Proteomes; UP000284878; Unassembled WGS sequence.
DR Proteomes; UP000433532; Unassembled WGS sequence.
DR Proteomes; UP000502341; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0015379; F:potassium:chloride symporter activity; IEA:InterPro.
DR InterPro; IPR003445; Cat_transpt.
DR InterPro; IPR004772; TrkH.
DR PANTHER; PTHR32024:SF3; TRK SYSTEM POTASSIUM UPTAKE PROTEIN; 1.
DR PANTHER; PTHR32024; TRK SYSTEM POTASSIUM UPTAKE PROTEIN TRKG-RELATED; 1.
DR Pfam; PF02386; TrkH; 1.
DR PIRSF; PIRSF006247; TrkH; 1.
PE 3: Inferred from homology;
KW Cell inner membrane {ECO:0000256|PIRNR:PIRNR006247};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW ECO:0000256|PIRNR:PIRNR006247};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065,
KW ECO:0000256|PIRNR:PIRNR006247};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PIRNR:PIRNR006247};
KW Metal-binding {ECO:0000256|PIRSR:PIRSR006247-1};
KW Potassium {ECO:0000256|ARBA:ARBA00022958, ECO:0000256|PIRNR:PIRNR006247};
KW Potassium transport {ECO:0000256|ARBA:ARBA00022538,
KW ECO:0000256|PIRNR:PIRNR006247};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR006247}.
FT TRANSMEM 12..34
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 40..61
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 73..94
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 135..159
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 180..203
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 237..261
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 273..293
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 334..355
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 395..416
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 457..482
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT BINDING 114
FT /ligand="K(+)"
FT /ligand_id="ChEBI:CHEBI:29103"
FT /evidence="ECO:0000256|PIRSR:PIRSR006247-1"
FT BINDING 221
FT /ligand="K(+)"
FT /ligand_id="ChEBI:CHEBI:29103"
FT /evidence="ECO:0000256|PIRSR:PIRSR006247-1"
FT BINDING 316
FT /ligand="K(+)"
FT /ligand_id="ChEBI:CHEBI:29103"
FT /evidence="ECO:0000256|PIRSR:PIRSR006247-1"
FT BINDING 317
FT /ligand="K(+)"
FT /ligand_id="ChEBI:CHEBI:29103"
FT /evidence="ECO:0000256|PIRSR:PIRSR006247-1"
FT BINDING 434
FT /ligand="K(+)"
FT /ligand_id="ChEBI:CHEBI:29103"
FT /evidence="ECO:0000256|PIRSR:PIRSR006247-1"
SQ SEQUENCE 484 AA; 52633 MW; 23F311A56E70A0D1 CRC64;
MALPTLRILG FIIGIFLITL AASMLVPILT MLAFDRTEGI QAFIWSSVAT FVTGLGLVLP
GRPEHVHLRP RDMYMLTVSS WVLVCIFAAL PFVLQQHISY TDAFFESMSG ITATGSTVLS
GLDDMSPGIL IWRSLLHWLG GIGFIAMAVA ILPMLRIGGM RLFQTESSDR SEKVLPRSHM
VAKYIVATYV GITLLGSLAF WGAGMSPFDA VNHAMSAIST GGFSTSDQSL AKWKQPAVHW
TAVVVMILGS LPFALYVATL RGHRKALIKD QQVRGLLGLL LVTWLLMGTW YAVTSKLPWM
DAFRIVAVNV TSVVTTTGFA LGDYSMWGHF SIMLFFYLGF IGGCSGSTAG GIKIFRFQVA
YTLLKANLYQ LIHPRAVLKQ NYNGHRLDEE IVRSILTFSF FFAIVVCLLA LCLSLIGLDW
MTALTGAAST VAGVGPGMGP IIGPSGNFAS LPDAAKWLLA AGMLLGRLEI ITVLVLLTPA
FWRH
//
