ID A0A0B5ARC6_9BACL Unreviewed; 506 AA.
AC A0A0B5ARC6;
DT 01-APR-2015, integrated into UniProtKB/TrEMBL.
DT 01-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE RecName: Full=Putative aldehyde dehydrogenase AldA {ECO:0000256|ARBA:ARBA00039869};
DE EC=1.2.1.3 {ECO:0000256|ARBA:ARBA00024226};
GN ORFNames=JMA_17610 {ECO:0000313|EMBL:AJD91078.1};
OS Jeotgalibacillus malaysiensis.
OC Bacteria; Bacillota; Bacilli; Bacillales; Planococcaceae; Jeotgalibacillus.
OX NCBI_TaxID=1508404 {ECO:0000313|EMBL:AJD91078.1, ECO:0000313|Proteomes:UP000031449};
RN [1] {ECO:0000313|EMBL:AJD91078.1, ECO:0000313|Proteomes:UP000031449}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=D5 {ECO:0000313|EMBL:AJD91078.1,
RC ECO:0000313|Proteomes:UP000031449};
RA Yaakop A.S., Chan K.-G., Goh K.M.;
RT "Complete genome of a marine bacteria Jeotgalibacillus malaysiensis.";
RL Submitted (AUG-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=an aldehyde + H2O + NAD(+) = a carboxylate + 2 H(+) + NADH;
CC Xref=Rhea:RHEA:16185, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:17478, ChEBI:CHEBI:29067, ChEBI:CHEBI:57540,
CC ChEBI:CHEBI:57945; EC=1.2.1.3;
CC Evidence={ECO:0000256|ARBA:ARBA00024149};
CC -!- SIMILARITY: Belongs to the aldehyde dehydrogenase family.
CC {ECO:0000256|RuleBase:RU003345}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP009416; AJD91078.1; -; Genomic_DNA.
DR RefSeq; WP_039809031.1; NZ_CP009416.1.
DR AlphaFoldDB; A0A0B5ARC6; -.
DR STRING; 1508404.JMA_17610; -.
DR KEGG; jeo:JMA_17610; -.
DR HOGENOM; CLU_005391_0_2_9; -.
DR OrthoDB; 9762913at2; -.
DR BioCyc; JESP1508404:G14D9-11016-MONOMER; -.
DR Proteomes; UP000031449; Chromosome.
DR GO; GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR CDD; cd07116; ALDH_ACDHII-AcoD; 1.
DR InterPro; IPR016161; Ald_DH/histidinol_DH.
DR InterPro; IPR016163; Ald_DH_C.
DR InterPro; IPR016160; Ald_DH_CS_CYS.
DR InterPro; IPR029510; Ald_DH_CS_GLU.
DR InterPro; IPR016162; Ald_DH_N.
DR InterPro; IPR015590; Aldehyde_DH_dom.
DR PANTHER; PTHR43111; ALDEHYDE DEHYDROGENASE B-RELATED; 1.
DR PANTHER; PTHR43111:SF1; ALDEHYDE DEHYDROGENASE B-RELATED; 1.
DR Pfam; PF00171; Aldedh; 1.
DR SUPFAM; SSF53720; ALDH-like; 1.
DR PROSITE; PS00070; ALDEHYDE_DEHYDR_CYS; 1.
DR PROSITE; PS00687; ALDEHYDE_DEHYDR_GLU; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000256|RuleBase:RU003345}.
FT DOMAIN 27..493
FT /note="Aldehyde dehydrogenase"
FT /evidence="ECO:0000259|Pfam:PF00171"
FT ACT_SITE 262
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10007"
SQ SEQUENCE 506 AA; 56147 MW; B0860298AA8EDAB5 CRC64;
MTYANPNTDG SLVNFKEKYD NFIGGEWVAP VKGQYFDNPS PVDGKTFCQI ARSTEEDIEK
ALDAAHAAKD AWGKTSVTER SVILNKIADR MEENLEMLAV AETWENGKAV RETLNADIPL
AIDHFRYFAG VIRAQEGTLG EIDHDTVAYH FHEPLGVVGQ IIPWNFPLLM AVWKLAPALA
AGNCVVLKPA EQTPSSILVL MELVGDLLPK GVVNIVNGFG LEAGKPLASS KRIAKIAFTG
ETTTGRMIME YASQNLIPVT LELGGKSPNI FFKDIMDQDD EFVDKAVEGL LMFALNQGEV
CTCPSRALIH EDIYDEFMAR VVKRVKEINT GNPLDPNTMM GAQASTEQME KIQKYLQIGK
EEGAELVTGG DINKKEGEFA EGYYIQPTIF KGTNDMRIFQ EEIFGPVLSV TTFKTDEEAM
EIANDTLYGL GAGIWTRNVN TAYRFGRGIQ AGRVWTNCYH QYPAHAAFGG YKMSGIGREN
HKMMLDHYQQ TKNMLVSYSP KKLGFF
//
