ID A0A0D8H3V7_ACIBA Unreviewed; 440 AA.
AC A0A0D8H3V7;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 27-MAR-2024, entry version 72.
DE RecName: Full=Glutaminase {ECO:0000256|ARBA:ARBA00012918, ECO:0000256|HAMAP-Rule:MF_00313};
DE EC=3.5.1.2 {ECO:0000256|ARBA:ARBA00012918, ECO:0000256|HAMAP-Rule:MF_00313};
GN Name=glsA {ECO:0000256|HAMAP-Rule:MF_00313,
GN ECO:0000313|EMBL:AVI34406.1};
GN ORFNames=A0141_RS03900 {ECO:0000313|EMBL:EHU2483385.1}, Aba7835_14680
GN {ECO:0000313|EMBL:QFY69830.1}, ABR2091_0950
GN {ECO:0000313|EMBL:CUW34357.1}, APD17_02685
GN {ECO:0000313|EMBL:KQD53055.1}, AYR68_04570
GN {ECO:0000313|EMBL:AML66321.1}, B7L45_14155
GN {ECO:0000313|EMBL:ARG02847.1}, B9W25_08785
GN {ECO:0000313|EMBL:PRN35219.1}, CAS83_05610
GN {ECO:0000313|EMBL:OTT25223.1}, CBL15_13240
GN {ECO:0000313|EMBL:AWW85922.1}, CSB70_0681
GN {ECO:0000313|EMBL:AVI34406.1}, CTZ19_14130
GN {ECO:0000313|EMBL:ATU57252.1}, CV954_014650
GN {ECO:0000313|EMBL:PQL81443.1}, DLI71_06400
GN {ECO:0000313|EMBL:QFX71300.1}, EA720_005625
GN {ECO:0000313|EMBL:QBH53232.1}, EGM95_15915
GN {ECO:0000313|EMBL:AYY90169.1}, F4T85_04710
GN {ECO:0000313|EMBL:MQZ67691.1}, FE003_14590
GN {ECO:0000313|EMBL:QCT16898.1}, FJU42_02175
GN {ECO:0000313|EMBL:TPU68668.1}, GSE42_05340
GN {ECO:0000313|EMBL:MYM77355.1}, HBK86_02875
GN {ECO:0000313|EMBL:QJH20340.1}, HIN86_14240
GN {ECO:0000313|EMBL:QJF36313.1}, IAG11_08375
GN {ECO:0000313|EMBL:MBD0219906.1}, IMO23_04705
GN {ECO:0000313|EMBL:QPF14238.1}, ITE13_01810
GN {ECO:0000313|EMBL:MBP4958257.1}, SAMEA104305318_00841
GN {ECO:0000313|EMBL:SST18689.1}, SAMEA4394745_00675
GN {ECO:0000313|EMBL:SSI23675.1};
OS Acinetobacter baumannii.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Moraxellales; Moraxellaceae;
OC Acinetobacter; Acinetobacter calcoaceticus/baumannii complex.
OX NCBI_TaxID=470 {ECO:0000313|EMBL:MBP4958257.1, ECO:0000313|Proteomes:UP000673677};
RN [1] {ECO:0000313|EMBL:KQD53055.1, ECO:0000313|Proteomes:UP000051023}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ABBL067b {ECO:0000313|EMBL:KQD53055.1,
RC ECO:0000313|Proteomes:UP000051023};
RA Ozer E.A., Fitzpatrick M.A., Hauser A.R.;
RT "The utility of whole genome sequencing in characterizing Acinetobacter
RT epidemiology and analyzing hospital outbreaks.";
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:CUW34357.1, ECO:0000313|Proteomes:UP000066661}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=R2091 {ECO:0000313|EMBL:CUW34357.1};
RA Wibberg D.;
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:AML66321.1, ECO:0000313|Proteomes:UP000070545}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=XH859 {ECO:0000313|EMBL:AML66321.1,
RC ECO:0000313|Proteomes:UP000070545};
RA Feng Y., Hua X., Yu Y.;
RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|EMBL:MYM77355.1, ECO:0000313|Proteomes:UP000480763}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DMS06669 {ECO:0000313|EMBL:MYM77355.1,
RC ECO:0000313|Proteomes:UP000480763};
RX PubMed=29137647;
RA Si-Tuan N., Ngoc H.M., Hang P.T.T., Nguyen C., Van P.H., Huong N.T.;
RT "New eight genes identified at the clinical multidrug-resistant
RT Acinetobacter baumannii DMS06669 strain in a Vietnam hospital.";
RL Ann. Clin. Microbiol. Antimicrob. 16:0-74(2017).
RN [5] {ECO:0000313|EMBL:PRN35219.1, ECO:0000313|Proteomes:UP000237823}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KUFAR57 {ECO:0000313|EMBL:PRN35219.1,
RC ECO:0000313|Proteomes:UP000237823};
RA Nasser K., Habibi N., Khan M.W., Purohit P., Al-Obaid I., Dhar R.,
RA Al-Fouzan W., Mustafa A.S.;
RT "Comparison of Acinetobacter baumannii whole genome sequences from two
RT major hospitals in Kuwait.";
RL Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
RN [6] {ECO:0000313|EMBL:ARG02847.1, ECO:0000313|Proteomes:UP000192723}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SAA14 {ECO:0000313|EMBL:ARG02847.1,
RC ECO:0000313|Proteomes:UP000192723};
RA Yoon E.-J., Kim J.O., Yang J.W., Kim H.S., Lee K.J., Jeong S.H., Lee H.,
RA Lee K.;
RT "Multiplied blaOXA-23-transposons in the genome of Acinetobacter spp. as an
RT adaptive mechanism for bacteria encountering carbapenems.";
RL Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
RN [7] {ECO:0000313|EMBL:AWW85922.1, ECO:0000313|Proteomes:UP000249421}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=XH731 {ECO:0000313|EMBL:AWW85922.1,
RC ECO:0000313|Proteomes:UP000249421};
RA Hua X., Yu Y.;
RT "The evolution of oxa-23 in Acinetobacter baumanni.";
RL Submitted (MAY-2017) to the EMBL/GenBank/DDBJ databases.
RN [8] {ECO:0000313|EMBL:OTT25223.1, ECO:0000313|Proteomes:UP000194553}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ARLG1317 {ECO:0000313|EMBL:OTT25223.1,
RC ECO:0000313|Proteomes:UP000194553};
RA Kreiswirth B., Manca C., Chen L., Evans S., Fowler V., Patel R.,
RA Chambers H., Bonomo R., Paul V., Sankar J., Gaind R., Ray P., Gautam V.,
RA Biswal M., Datta S., Walia K., Adams M., Nelson K., Sutton G., Fouts D.,
RA Hujer K., Hujer A.;
RL Submitted (MAY-2017) to the EMBL/GenBank/DDBJ databases.
RN [9] {ECO:0000313|EMBL:ATU57252.1, ECO:0000313|Proteomes:UP000229219}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Ab4568 {ECO:0000313|EMBL:ATU57252.1,
RC ECO:0000313|Proteomes:UP000229219};
RA Liu X.;
RT "Genome analysis of an Acinetobacter baumannii outbreak in hospital ICU in
RT China.";
RL Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
RN [10] {ECO:0000313|EMBL:PQL81443.1, ECO:0000313|Proteomes:UP000233757}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ZQ8 {ECO:0000313|EMBL:PQL81443.1,
RC ECO:0000313|Proteomes:UP000233757};
RA Qasim Z.J.;
RT "Acinetobacter baumanii whole genome sequence.";
RL Submitted (FEB-2018) to the EMBL/GenBank/DDBJ databases.
RN [11] {ECO:0000313|EMBL:AVI34406.1, ECO:0000313|Proteomes:UP000257523}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AR_0070 {ECO:0000313|EMBL:AVI34406.1,
RC ECO:0000313|Proteomes:UP000257523};
RA Benahmed F.H., Lutgring J.D., Yoo B., Machado M., Brown A., McAllister G.,
RA Perry A., Halpin A.L., Vavikolanu K., Ott S., Zhao X., Tallon L.,
RA Sadzewicz L., Aluvathingal J., Nadendla S., Voskania-kordi A., Simonyan V.,
RA Patel J., Shawar R.M.;
RT "FDA/CDC Antimicrobial Resistant Isolate Bank Genome Sequencing.";
RL Submitted (FEB-2018) to the EMBL/GenBank/DDBJ databases.
RN [12] {ECO:0000313|Proteomes:UP000252694, ECO:0000313|Proteomes:UP000262697}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=4300STDY6542375 {ECO:0000313|EMBL:SSI23675.1,
RC ECO:0000313|Proteomes:UP000262697}, and 4300STDY7045823
RC {ECO:0000313|EMBL:SST18689.1, ECO:0000313|Proteomes:UP000252694};
RG Pathogen Informatics;
RL Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases.
RN [13] {ECO:0000313|EMBL:QFY69830.1, ECO:0000313|Proteomes:UP000326952}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=7835 {ECO:0000313|EMBL:QFY69830.1,
RC ECO:0000313|Proteomes:UP000326952};
RA Salgado-Camargo A.D., Castro-Jaimes S., Silva-Sanchez J.,
RA Volkow-Fernandez P., Castillo-Ramirez S., Cevallos M.A.;
RT "Evolution of Acinetobacter baumannii plasmids.";
RL Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases.
RN [14] {ECO:0000313|Proteomes:UP000268766}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TG60155 {ECO:0000313|Proteomes:UP000268766};
RA Sahl J.W.;
RT "GWAS and RNA-Seq identify cryptic mechanisms of antimicrobial resistance
RT in Acinetobacter baumannii.";
RL Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases.
RN [15] {ECO:0000313|EMBL:QBH53232.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=TG60155 {ECO:0000313|EMBL:QBH53232.1};
RA Sahl J.W.;
RL Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases.
RN [16] {ECO:0000313|EMBL:AYY90169.1, ECO:0000313|Proteomes:UP000273577}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MRSN15313 {ECO:0000313|EMBL:AYY90169.1,
RC ECO:0000313|Proteomes:UP000273577};
RA Sorenson N.M., Snesrud E., Xavier D.E., Cacci L.C., Oeleman W.,
RA Iavarone A.T., Mc Gann P., Riley L.W., Moreira B.M.;
RT "A novel plasmid carries a functional mcr-4.3 gene in a colistin-resistant
RT Acinetobacter baumannii clinical strain.";
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
RN [17] {ECO:0000313|EMBL:QBH53232.1, ECO:0000313|Proteomes:UP000268766}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TG60155 {ECO:0000313|EMBL:QBH53232.1,
RC ECO:0000313|Proteomes:UP000268766};
RA Sahl J.;
RT "Comparative genomics and transcriptomics of Acinetobacter baumannii.";
RL Submitted (FEB-2019) to the EMBL/GenBank/DDBJ databases.
RN [18] {ECO:0000313|EMBL:QCT16898.1, ECO:0000313|Proteomes:UP000300722}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PB364 {ECO:0000313|EMBL:QCT16898.1,
RC ECO:0000313|Proteomes:UP000300722};
RA Huang W., Wang G., Yin C., Chen D., Dhand A., Chanza M., Dimitrova N.,
RA Fallon J.T.;
RT "Optimizing a Whole-Genome Sequencing Data Processing Pipeline for
RT Precision Surveillance of Healthcare-Associated Infections.";
RL Submitted (MAY-2019) to the EMBL/GenBank/DDBJ databases.
RN [19] {ECO:0000313|EMBL:TPU68668.1, ECO:0000313|Proteomes:UP000315888}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MRSN14237 {ECO:0000313|EMBL:TPU68668.1,
RC ECO:0000313|Proteomes:UP000315888};
RA Mcgann P., Snesrud E., Galac M.R.;
RT "A Diverse Panel of Clinical Acinetobacter baumannii for Research Use.";
RL Submitted (JUN-2019) to the EMBL/GenBank/DDBJ databases.
RN [20] {ECO:0000313|EMBL:QFX71300.1, ECO:0000313|Proteomes:UP000325982}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=6507 {ECO:0000313|EMBL:QFX71300.1,
RC ECO:0000313|Proteomes:UP000325982};
RA Paul V., Sankar M.J., Gaind R., Ray P., Gautam V., Biswal M., Datta S.,
RA Walia K., Kreiswirth B., Evans S., Fowler V., Patel R., Chambers H.C.,
RA Bonomo R.A., Hujer K.M., Huker A., Adams M., Clarke T.H., Sutton G.,
RA Nierman W.C., Nelson K.E., Fouts D.E.;
RT "10 Multi-Drug Resistant Acinetobacter Baumannii Strains for ARLG-ICMR From
RT India.";
RL Submitted (SEP-2019) to the EMBL/GenBank/DDBJ databases.
RN [21] {ECO:0000313|EMBL:MQZ67691.1, ECO:0000313|Proteomes:UP000420346}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AMA26 {ECO:0000313|EMBL:MQZ67691.1,
RC ECO:0000313|Proteomes:UP000420346};
RA Maria R.S., Adams M.D.;
RT "Distinct mechanisms of dissemination of NDM-1 metallo-beta-betalactamase
RT in Acinetobacter species spp. in Argentina.";
RL Submitted (SEP-2019) to the EMBL/GenBank/DDBJ databases.
RN [22] {ECO:0000313|EMBL:MYM77355.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=DMS06669 {ECO:0000313|EMBL:MYM77355.1};
RA Nguyen S.-T.;
RL Submitted (DEC-2019) to the EMBL/GenBank/DDBJ databases.
RN [23] {ECO:0000313|EMBL:QJH20340.1, ECO:0000313|Proteomes:UP000502990}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VB82 {ECO:0000313|EMBL:QJH20340.1,
RC ECO:0000313|Proteomes:UP000502990};
RA Veeraraghavan B., Vijayakumar S., Amala A., Francis L., Kirubananthan A.;
RT "Complete genome of Carbapenem Resistant Acinetobacter baumannii.";
RL Submitted (MAR-2020) to the EMBL/GenBank/DDBJ databases.
RN [24] {ECO:0000313|EMBL:QJF36313.1, ECO:0000313|Proteomes:UP000501210}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Ab-B004d-c {ECO:0000313|EMBL:QJF36313.1,
RC ECO:0000313|Proteomes:UP000501210};
RA Ayibieke A., Saito R.;
RT "Whole-genome sequence analysis of carbapanemase producing Acinetobacter
RT baumannii isolates from Ghana.";
RL Submitted (APR-2020) to the EMBL/GenBank/DDBJ databases.
RN [25] {ECO:0000313|EMBL:MBD0219906.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=A86 {ECO:0000313|EMBL:MBD0219906.1};
RA Abouelfetouh A., Mattock J., Turner D., Li E., Evans B.A.;
RT "Diversity of carbapenem-resistant Acinetobacter baumannii and
RT bacteriophage-mediated spread of the Oxa23 carbapenemase.";
RL Submitted (AUG-2020) to the EMBL/GenBank/DDBJ databases.
RN [26] {ECO:0000313|EMBL:QPF14238.1, ECO:0000313|Proteomes:UP000594659}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Res13-Abat-PEA21-P4-01-A {ECO:0000313|EMBL:QPF14238.1,
RC ECO:0000313|Proteomes:UP000594659};
RA Poulin-Laprade D., Brouard J.-S., Gagnon N., Turcotte A., Langlois A.,
RA Matte J.J., Carrillo C.D., Zaheer R., McAllister T., Topp E., Talbot G.;
RT "Resistance determinants and their genetic context in bacteria from a
RT longitudinal study of pigs reared under conventional and antibiotic-free
RT husbandry practices.";
RL Submitted (SEP-2020) to the EMBL/GenBank/DDBJ databases.
RN [27] {ECO:0000313|EMBL:MBP4958257.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=E314 {ECO:0000313|EMBL:MBP4958257.1};
RA Frenk S., Rakovitsky N.;
RT "Epidemiology and genetic characterization of 247 CRAB isolated from
RT infections.";
RL Submitted (DEC-2020) to the EMBL/GenBank/DDBJ databases.
RN [28] {ECO:0000313|EMBL:EHU2483385.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=MRSN7100 {ECO:0000313|EMBL:EHU2483385.1};
RA Mcgann P.T.;
RL Submitted (JUL-2021) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=H2O + L-glutamine = L-glutamate + NH4(+);
CC Xref=Rhea:RHEA:15889, ChEBI:CHEBI:15377, ChEBI:CHEBI:28938,
CC ChEBI:CHEBI:29985, ChEBI:CHEBI:58359; EC=3.5.1.2;
CC Evidence={ECO:0000256|ARBA:ARBA00001062, ECO:0000256|HAMAP-
CC Rule:MF_00313};
CC -!- SUBUNIT: Homotetramer. {ECO:0000256|ARBA:ARBA00011881,
CC ECO:0000256|HAMAP-Rule:MF_00313}.
CC -!- SIMILARITY: Belongs to the glutaminase family.
CC {ECO:0000256|ARBA:ARBA00011076, ECO:0000256|HAMAP-Rule:MF_00313}.
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DR EMBL; CP014539; AML66321.1; -; Genomic_DNA.
DR EMBL; CP020579; ARG02847.1; -; Genomic_DNA.
DR EMBL; CP024613; ATU57252.1; -; Genomic_DNA.
DR EMBL; CP027178; AVI34406.1; -; Genomic_DNA.
DR EMBL; CP021321; AWW85922.1; -; Genomic_DNA.
DR EMBL; CP033869; AYY90169.1; -; Genomic_DNA.
DR EMBL; LN997846; CUW34357.1; -; Genomic_DNA.
DR EMBL; AAYNHF020000002; EHU2483385.1; -; Genomic_DNA.
DR EMBL; LLFO01000100; KQD53055.1; -; Genomic_DNA.
DR EMBL; JACSVK010000016; MBD0219906.1; -; Genomic_DNA.
DR EMBL; JAEHMK010000002; MBP4958257.1; -; Genomic_DNA.
DR EMBL; VYTH01000004; MQZ67691.1; -; Genomic_DNA.
DR EMBL; WWCH01000001; MYM77355.1; -; Genomic_DNA.
DR EMBL; NGHO01000026; OTT25223.1; -; Genomic_DNA.
DR EMBL; PHJU02000033; PQL81443.1; -; Genomic_DNA.
DR EMBL; NEPB01000014; PRN35219.1; -; Genomic_DNA.
DR EMBL; CP036283; QBH53232.1; -; Genomic_DNA.
DR EMBL; CP040425; QCT16898.1; -; Genomic_DNA.
DR EMBL; CP045528; QFX71300.1; -; Genomic_DNA.
DR EMBL; CP033243; QFY69830.1; -; Genomic_DNA.
DR EMBL; CP051875; QJF36313.1; -; Genomic_DNA.
DR EMBL; CP050385; QJH20340.1; -; Genomic_DNA.
DR EMBL; CP062919; QPF14238.1; -; Genomic_DNA.
DR EMBL; UFDJ01000002; SSI23675.1; -; Genomic_DNA.
DR EMBL; UFMQ01000002; SST18689.1; -; Genomic_DNA.
DR EMBL; VHGY01000007; TPU68668.1; -; Genomic_DNA.
DR RefSeq; WP_000856712.1; NZ_WYAT01000018.1.
DR KEGG; abw:BL01_11520; -.
DR OMA; RNPMINS; -.
DR Proteomes; UP000051023; Unassembled WGS sequence.
DR Proteomes; UP000066661; Chromosome I.
DR Proteomes; UP000070545; Chromosome.
DR Proteomes; UP000192723; Chromosome.
DR Proteomes; UP000194553; Unassembled WGS sequence.
DR Proteomes; UP000229219; Chromosome.
DR Proteomes; UP000233757; Unassembled WGS sequence.
DR Proteomes; UP000237823; Unassembled WGS sequence.
DR Proteomes; UP000249421; Chromosome.
DR Proteomes; UP000252694; Unassembled WGS sequence.
DR Proteomes; UP000257523; Chromosome.
DR Proteomes; UP000262697; Unassembled WGS sequence.
DR Proteomes; UP000268766; Chromosome.
DR Proteomes; UP000273577; Chromosome.
DR Proteomes; UP000300722; Chromosome.
DR Proteomes; UP000315888; Unassembled WGS sequence.
DR Proteomes; UP000325982; Chromosome.
DR Proteomes; UP000326952; Chromosome.
DR Proteomes; UP000420346; Unassembled WGS sequence.
DR Proteomes; UP000480763; Unassembled WGS sequence.
DR Proteomes; UP000501210; Chromosome.
DR Proteomes; UP000502990; Chromosome.
DR Proteomes; UP000594659; Chromosome.
DR Proteomes; UP000634608; Unassembled WGS sequence.
DR Proteomes; UP000673677; Unassembled WGS sequence.
DR Proteomes; UP000737470; Unassembled WGS sequence.
DR GO; GO:0004359; F:glutaminase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006541; P:glutamine metabolic process; IEA:InterPro.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.30.750.24; STAS domain; 1.
DR HAMAP; MF_00313; Glutaminase; 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR015868; Glutaminase.
DR InterPro; IPR002645; STAS_dom.
DR InterPro; IPR036513; STAS_dom_sf.
DR NCBIfam; TIGR03814; Gln_ase; 1.
DR PANTHER; PTHR12544; GLUTAMINASE; 1.
DR PANTHER; PTHR12544:SF29; GLUTAMINASE; 1.
DR Pfam; PF04960; Glutaminase; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR SUPFAM; SSF52091; SpoIIaa-like; 1.
DR PROSITE; PS50801; STAS; 1.
PE 3: Inferred from homology;
KW Acetylation {ECO:0000256|HAMAP-Rule:MF_00313};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|HAMAP-Rule:MF_00313}.
FT DOMAIN 316..398
FT /note="STAS"
FT /evidence="ECO:0000259|PROSITE:PS50801"
FT BINDING 64
FT /ligand="substrate"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00313"
FT BINDING 113
FT /ligand="substrate"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00313"
FT BINDING 157
FT /ligand="substrate"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00313"
FT BINDING 164
FT /ligand="substrate"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00313"
FT BINDING 188
FT /ligand="substrate"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00313"
FT BINDING 240
FT /ligand="substrate"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00313"
FT BINDING 258
FT /ligand="substrate"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00313"
SQ SEQUENCE 440 AA; 48239 MW; B7DF0E5867FF435C CRC64;
MKTPLPDYLA NVIEACDIDN SGHLADYIPE LANANPNRLA LAMSTVDGEI YSVGDDDVEF
TIQSISKPFV YAYVLQQLGI DAVLAKVGVE PSGEAFNEIS LGKDGRPKNP MINSGAITVH
SLIQVKHGLH SAEILRRFMS ELAGRELSFD ESVYDSEVKT AYRNLSIGYM LRTVGILETD
PVDIVNGYIR QCAIMVTVKD LVRMGSVLAN GGVDPKTGKR LLNRSVVRQV LSVMMSCGMY
DAAGDWLSTV GIPAKSGVAG GILGVLPGQV SIAAFSPRLD EHGHSVRGID ILERLSRDMG
LHLMEGTPSA QTIVQSHYRT GKDASLSVYV LRGVLKFTEA EMLLRILQDE TTDQSTIVID
LTQISLIHDV GKRMFLEGVD RLIDDGHTLV LVDPEQRLDH ARTAKDRELH VYHDFDDLLE
KHEIPAKKKT YSDIAALLNC
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