ID A0A0E3SST3_METMT Unreviewed; 469 AA.
AC A0A0E3SST3;
DT 24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT 24-JUN-2015, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=Aldehyde dehydrogenase {ECO:0000313|EMBL:AKB85673.1};
DE EC=1.2.1.3 {ECO:0000313|EMBL:AKB85673.1};
GN ORFNames=MCMEM_1620 {ECO:0000313|EMBL:AKB85673.1};
OS Methanococcoides methylutens MM1.
OC Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC Methanosarcinales; Methanosarcinaceae; Methanococcoides.
OX NCBI_TaxID=1434104 {ECO:0000313|EMBL:AKB85673.1, ECO:0000313|Proteomes:UP000033048};
RN [1] {ECO:0000313|EMBL:AKB85673.1, ECO:0000313|Proteomes:UP000033048}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MM1 {ECO:0000313|EMBL:AKB85673.1,
RC ECO:0000313|Proteomes:UP000033048};
RA Henriksen J.R., Luke J., Reinhart S., Benedict M.N., Youngblut N.D.,
RA Metcalf M.E., Whitaker R.J., Metcalf W.W.;
RT "Methanogenic archaea and the global carbon cycle.";
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the aldehyde dehydrogenase family.
CC {ECO:0000256|ARBA:ARBA00009986, ECO:0000256|RuleBase:RU003345}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP009518; AKB85673.1; -; Genomic_DNA.
DR RefSeq; WP_052721390.1; NZ_CP009518.1.
DR AlphaFoldDB; A0A0E3SST3; -.
DR STRING; 1434104.MCMEM_1620; -.
DR GeneID; 24894182; -.
DR KEGG; mmet:MCMEM_1620; -.
DR PATRIC; fig|1434104.5.peg.1760; -.
DR HOGENOM; CLU_005391_3_1_2; -.
DR OrthoDB; 6342at2157; -.
DR Proteomes; UP000033048; Chromosome.
DR GO; GO:0004029; F:aldehyde dehydrogenase (NAD+) activity; IEA:UniProtKB-EC.
DR GO; GO:0043878; F:glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity; IEA:UniProtKB-EC.
DR GO; GO:0006081; P:cellular aldehyde metabolic process; IEA:InterPro.
DR InterPro; IPR016161; Ald_DH/histidinol_DH.
DR InterPro; IPR016163; Ald_DH_C.
DR InterPro; IPR016160; Ald_DH_CS_CYS.
DR InterPro; IPR029510; Ald_DH_CS_GLU.
DR InterPro; IPR016162; Ald_DH_N.
DR InterPro; IPR015590; Aldehyde_DH_dom.
DR InterPro; IPR012394; Aldehyde_DH_NAD(P).
DR PANTHER; PTHR43570; ALDEHYDE DEHYDROGENASE; 1.
DR PANTHER; PTHR43570:SF16; ALDEHYDE DEHYDROGENASE TYPE III, ISOFORM Q; 1.
DR Pfam; PF00171; Aldedh; 1.
DR PIRSF; PIRSF036492; ALDH; 1.
DR SUPFAM; SSF53720; ALDH-like; 1.
DR PROSITE; PS00070; ALDEHYDE_DEHYDR_CYS; 1.
DR PROSITE; PS00687; ALDEHYDE_DEHYDR_GLU; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|RuleBase:RU003345,
KW ECO:0000313|EMBL:AKB85673.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000033048}.
FT DOMAIN 5..437
FT /note="Aldehyde dehydrogenase"
FT /evidence="ECO:0000259|Pfam:PF00171"
FT ACT_SITE 213
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10007"
SQ SEQUENCE 469 AA; 53036 MW; 6311C42487C94BD5 CRC64;
MCLEIQQVFE IQKKNAPYLA RANAEERLER IRRIENYLQD EERLSDLYKA MYADLHKPET
EVIATEVGVV QAHINHVKRN LHKWMKDTKV PTPLPLIGTR SHIRYEPKGV VLIIAPWNFP
FNLTLVPLIY AIAAGNAAIL KPSEMAANTS AYISLMMYEL FDESEVAVFE GNESVAQQLL
DLPFNHVFFT GSPRVGKKVM SRAAEHLSSV TLELGGKSPA IVDETANVKK IAKNLAWAKF
INNGQACIAP DYLIVHESAR DGFVNEFGKA IEQLYDPSGE GIRNSSDYCR IINDHHYNRL
LTLYNDACEK DARVLYGGDF DDSDLYIAPT LLENVSGDMK IMQEEIFGPL LPMITYRNRE
DVIPVIEQNP SPLILYIASE NQGNIDYFMD SIPSGSTLTN DYMLSYSNPH LPFGGINSSG
IGKSLGFHGF VGFSNERAVM QRKWGSMGML YPPYSENIRK IFRTIYRWM
//
