ID A0A0H3G7T2_BRUSU Unreviewed; 607 AA.
AC A0A0H3G7T2;
DT 16-SEP-2015, integrated into UniProtKB/TrEMBL.
DT 16-SEP-2015, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Penicillin-binding protein {ECO:0000313|EMBL:AEM18766.1};
GN OrderedLocusNames=BS1330_I1431 {ECO:0000313|EMBL:AEM18766.1};
OS Brucella suis biovar 1 (strain 1330).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Brucellaceae; Brucella/Ochrobactrum group; Brucella.
OX NCBI_TaxID=204722 {ECO:0000313|EMBL:AEM18766.1, ECO:0000313|Proteomes:UP000007104};
RN [1] {ECO:0000313|EMBL:AEM18766.1, ECO:0000313|Proteomes:UP000007104}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1330 {ECO:0000313|EMBL:AEM18766.1,
RC ECO:0000313|Proteomes:UP000007104};
RX PubMed=22038969; DOI=10.1128/JB.06181-11;
RA Tae H., Shallom S., Settlage R., Preston D., Adams L.G., Garner H.R.;
RT "Revised genome sequence of Brucella suis 1330.";
RL J. Bacteriol. 193:6410-6410(2011).
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DR EMBL; CP002997; AEM18766.1; -; Genomic_DNA.
DR RefSeq; WP_002964545.1; NZ_KN046804.1.
DR AlphaFoldDB; A0A0H3G7T2; -.
DR GeneID; 58775513; -.
DR KEGG; bsi:BS1330_I1431; -.
DR PATRIC; fig|204722.21.peg.925; -.
DR HOGENOM; CLU_009289_6_2_5; -.
DR PhylomeDB; A0A0H3G7T2; -.
DR Proteomes; UP000007104; Chromosome I.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR Gene3D; 3.30.450.330; -; 1.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR005311; PBP_dimer.
DR InterPro; IPR036138; PBP_dimer_sf.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR PANTHER; PTHR30627:SF1; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE FTSI; 1.
DR Pfam; PF03717; PBP_dimer; 1.
DR Pfam; PF00905; Transpeptidase; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 49..72
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 89..200
FT /note="Penicillin-binding protein dimerisation"
FT /evidence="ECO:0000259|Pfam:PF03717"
FT DOMAIN 261..561
FT /note="Penicillin-binding protein transpeptidase"
FT /evidence="ECO:0000259|Pfam:PF00905"
FT REGION 586..607
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 607 AA; 66126 MW; 1397201D4B1A1993 CRC64;
MRLRLFSAKK KAPDGSIHGE VPAGDEKLAG NMAFVGSRKR HGNRARNRLW MAIACFAGIY
GVMAGKLVYF GMIGGVDQDA AGPFVHQLAS RPDILDRNGE ILATDIKTAS LYAEPRKIVD
PDETIEMLST VLPDLDWEAT YKRLKSGAGF VWIKRGLTPK QQSQIMALGV PGIGFRTEKR
RFYPGGPTAS HILGLVNVDN QGIAGMEKYI DSQGLSDLRS VGLATGQSLE PVHLSIDIRV
QHIMRDVLVK AMERYRAIAA GAVVLNVKTG EVIAMSSVPD FDPNNPVHAL DKDRLNRMSA
GTYEMGSTIK SFTTAMALDS GKFTLQSKLD ASRPLVFGRQ TIRDFHGKGR WLTLPEVFIF
SSNIGSGREA DAVGIEGHRA FLKKIGLLDR MQTELPEVAR PVEPRVWKKV HSMTISFGHG
MMTTPLQTAV GAAALMNGGK LIEPTFLPRT EAQAARASKQ VIHPQVSADM RYLYRLNSTA
PGGSGRRATV PGYRVGGKTG TAEKVINGRY SKDVRFNAFL ASFPMDNPTY VVLTIIDEPK
PEEGKFSATA GLNAAPMVAE IIRRSASFLG VSPDFRKEAL PASVENVSGR PDFQQEVPPA
MVSNEYD
//
