ID A0A0H3KAI3_STAAE Unreviewed; 1501 AA.
AC A0A0H3KAI3;
DT 16-SEP-2015, integrated into UniProtKB/TrEMBL.
DT 16-SEP-2015, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE RecName: Full=YSIRK-type signal peptide-containing protein {ECO:0008006|Google:ProtNLM};
GN OrderedLocusNames=NWMN_2392 {ECO:0000313|EMBL:BAF68664.1};
OS Staphylococcus aureus (strain Newman).
OC Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
OC Staphylococcus.
OX NCBI_TaxID=426430 {ECO:0000313|EMBL:BAF68664.1, ECO:0000313|Proteomes:UP000006386};
RN [1] {ECO:0000313|EMBL:BAF68664.1, ECO:0000313|Proteomes:UP000006386}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Newman {ECO:0000313|EMBL:BAF68664.1,
RC ECO:0000313|Proteomes:UP000006386};
RX PubMed=17951380; DOI=10.1128/JB.01000-07;
RA Baba T., Bae T., Schneewind O., Takeuchi F., Hiramatsu K.;
RT "Genome sequence of Staphylococcus aureus strain Newman and comparative
RT analysis of staphylococcal genomes: polymorphism and evolution of two major
RT pathogenicity islands.";
RL J. Bacteriol. 190:300-310(2008).
CC -!- SUBCELLULAR LOCATION: Secreted, cell wall
CC {ECO:0000256|ARBA:ARBA00004168}; Peptidoglycan-anchor
CC {ECO:0000256|ARBA:ARBA00004168}.
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DR EMBL; AP009351; BAF68664.1; -; Genomic_DNA.
DR KEGG; sae:NWMN_2392; -.
DR HOGENOM; CLU_000977_4_0_9; -.
DR Proteomes; UP000006386; Chromosome.
DR Gene3D; 2.20.230.30; -; 4.
DR Gene3D; 2.60.120.200; -; 1.
DR Gene3D; 2.20.230.10; Resuscitation-promoting factor rpfb; 1.
DR InterPro; IPR011098; G5_dom.
DR InterPro; IPR019931; LPXTG_anchor.
DR InterPro; IPR031477; SasG_E.
DR InterPro; IPR005877; YSIRK_signal_dom.
DR NCBIfam; TIGR01167; LPXTG_anchor; 1.
DR NCBIfam; TIGR01168; YSIRK_signal; 1.
DR PANTHER; PTHR37824; IRON-REGULATED SURFACE DETERMINANT PROTEIN C; 1.
DR PANTHER; PTHR37824:SF1; IRON-REGULATED SURFACE DETERMINANT PROTEIN C; 1.
DR Pfam; PF18483; Bact_lectin; 1.
DR Pfam; PF07501; G5; 8.
DR Pfam; PF00746; Gram_pos_anchor; 1.
DR Pfam; PF17041; SasG_E; 7.
DR Pfam; PF04650; YSIRK_signal; 1.
DR SMART; SM01208; G5; 8.
DR PROSITE; PS51109; G5; 8.
DR PROSITE; PS50847; GRAM_POS_ANCHORING; 1.
PE 4: Predicted;
KW Cell wall {ECO:0000256|ARBA:ARBA00022512};
KW Peptidoglycan-anchor {ECO:0000256|ARBA:ARBA00023088};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Secreted {ECO:0000256|ARBA:ARBA00022512};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT DOMAIN 421..503
FT /note="G5"
FT /evidence="ECO:0000259|PROSITE:PS51109"
FT DOMAIN 549..631
FT /note="G5"
FT /evidence="ECO:0000259|PROSITE:PS51109"
FT DOMAIN 677..759
FT /note="G5"
FT /evidence="ECO:0000259|PROSITE:PS51109"
FT DOMAIN 805..887
FT /note="G5"
FT /evidence="ECO:0000259|PROSITE:PS51109"
FT DOMAIN 933..1015
FT /note="G5"
FT /evidence="ECO:0000259|PROSITE:PS51109"
FT DOMAIN 1061..1143
FT /note="G5"
FT /evidence="ECO:0000259|PROSITE:PS51109"
FT DOMAIN 1189..1271
FT /note="G5"
FT /evidence="ECO:0000259|PROSITE:PS51109"
FT DOMAIN 1317..1399
FT /note="G5"
FT /evidence="ECO:0000259|PROSITE:PS51109"
FT DOMAIN 1469..1501
FT /note="Gram-positive cocci surface proteins LPxTG"
FT /evidence="ECO:0000259|PROSITE:PS50847"
FT REGION 77..145
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 442..469
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 498..1475
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 94..123
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 442..460
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 504..528
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 554..588
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 632..656
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 682..716
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 760..784
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 810..844
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 888..912
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 938..972
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1016..1040
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1066..1100
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1144..1168
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1194..1228
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1248..1277
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1305..1320
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1330..1354
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1355..1369
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1387..1411
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1437..1472
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1501 AA; 164725 MW; 052471FD600724F3 CRC64;
MQMRDKKGPV NKRVDFLSNK LNKYSIRKFT VGTASILIGS LMYLGTQQEA EAAENNIENP
TTLKDNVQSK EVKIEEVTNK DTAPQGVEAK SEVTSNKDTI EHEPSVKAED ISKKEDTPKE
VADVAEVQPK SSVTHNAETP KVRKARSVDE GSFDITRDSK NVVESTPITI QGKEHFEGYG
SVDIQKKPTD LGVSEVTRFN VGNESNGLIG ALQLKNKIDF SKDFNFKVRV ANNHQSNTTG
ADGWGFLFSK GNAEEYLTNG GILGDKGLVN SGGFKIDTGY IYTSSMDKTE KQAGQGYRGY
GAFVKNDSSG NSQMVGENID KSKTNFLNYA DNSTNTSDGK FHGQRLNDVI LTYVASTGKM
RAEYAGKTWE TSITDLGLSK NQAYNFLITS SQRWGLNQGI NANGWMRTDL KGSEFTFTPE
APKTITELEK KVEEIPFKKE RKFNPDLAPG TEKVTREGQK GEKTITTPTL KNPLTGVIIS
KGEPKEEITK DPINELTEYG PETIAPGHRD EFDPKLPTGK KEEVPGKPGI KNPETGDVVR
PPVDSVTKYG PVKGDSIVEK EEIPFEKERK FNPDLAPGTE KVTREGQKGE KTITTPTLKN
PLTGEIISKG ESKEEITKDP INELTEYGPE TITPGHRDEF DPKLPTGEKE EVPGKPGIKN
PETGDVVRPP VDSVTKYGPV KGDSIVEKEE IPFEKERKFN PDLAPGTEKV TREGQKGEKT
ITTPTLKNPL TGVIISKGEP KEEITKDPIN ELTEYGPETI TPGHRDEFDP KLPTGEKEEV
PGKPGIKNPE TGDVVRPPVD SVTKYGPVKG DSIVEKEEIP FKKERKFNPD LAPGTEKVTR
EGQKGEKTIT TPTLKNPLTG EIISKGESKE EITKDPINEL TEYGPETITP GHRDEFDPKL
PTGEKEEVPG KPGIKNPETG DVVRPPVDSV TKYGPVKGDS IVEKEEIPFK KERKFNPDLA
PGTEKVTREG QKGEKTITTP TLKNPLTGEI ISKGESKEEI TKDPINELTE YGPETITPGH
RDEFDPKLPT GEKEEVPGKP GIKNPETGDV VRPPVDSVTK YGPVKGDSIV EKEEIPFEKE
RKFNPDLAPG TEKVTREGQK GEKTITTPTL KNPLTGEIIS KGESKEEITK DPINELTEYG
PETITPGHRD EFDPKLPTGE KEEVPGKPGI KNPETGDVVR PPVDSVTKYG PVKGDSIVEK
EEIPFEKERK FNPDLAPGTE KVTREGQKGE KTITTPTLKN PLTGEIISKG ESKEEITKDP
VNELTEFGGE KIPQGHKDIF DPNLPTDQTE KVPGKPGIKN PDTGKVIEEP VDDVIKHGPK
TGTPETKTVE IPFETKREFN PKLQPGEERV KQEGQPGSKT ITTPITVNPL TGEKVGEGQP
TEEITKQPVD KIVEFGGEKP KDPKGPENPE KPSRPTHPSG PVNPNNPGLS KDRAKPNGPV
HSMDKNDKVK KSKIAKESVA NQEKKRAELP KTGLESTQKG LIFSSIIGIA GLMLLARRRK
N
//
