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Database: UniProt/TrEMBL
Entry: A0A0M4DHN8_STRPR
LinkDB: A0A0M4DHN8_STRPR
Original site: A0A0M4DHN8_STRPR 
ID   A0A0M4DHN8_STRPR        Unreviewed;      1272 AA.
AC   A0A0M4DHN8;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   07-JUN-2017, entry version 9.
DE   SubName: Full=Alpha-ketoglutarate decarboxylase {ECO:0000313|EMBL:ALC20905.1};
GN   ORFNames=SPRI_2599 {ECO:0000313|EMBL:ALC20905.1};
OS   Streptomyces pristinaespiralis.
OC   Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
OC   Streptomyces.
OX   NCBI_TaxID=38300 {ECO:0000313|EMBL:ALC20905.1};
RN   [1] {ECO:0000313|EMBL:ALC20905.1, ECO:0000313|Proteomes:UP000060513}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=HCCB 10218 {ECO:0000313|EMBL:ALC20905.1,
RC   ECO:0000313|Proteomes:UP000060513};
RA   Tian J., Yang J., Li L., Ruan L., Wei W., Zheng G., Wei Z., Yang S.,
RA   Ge M., Jiang W., Lu Y.;
RT   "Genome sequence of the pristinamycin over-producing bacterium
RT   Streptomyces pristinaespiralis HCCB10218.";
RL   Submitted (AUG-2015) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CP011340; ALC20905.1; -; Genomic_DNA.
DR   RefSeq; WP_053557736.1; NZ_CP011340.1.
DR   EnsemblBacteria; ALC20905; ALC20905; SPRI_2599.
DR   KEGG; spri:SPRI_2599; -.
DR   PATRIC; fig|38300.4.peg.2742; -.
DR   KO; K00164; -.
DR   Proteomes; UP000060513; Chromosome.
DR   GO; GO:0004591; F:oxoglutarate dehydrogenase (succinyl-transferring) activity; IEA:InterPro.
DR   GO; GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
DR   GO; GO:0016746; F:transferase activity, transferring acyl groups; IEA:InterPro.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; IEA:InterPro.
DR   InterPro; IPR001078; 2-oxoacid_DH_actylTfrase.
DR   InterPro; IPR032106; 2-oxogl_dehyd_N.
DR   InterPro; IPR011603; 2oxoglutarate_DH_E1.
DR   InterPro; IPR001017; DH_E1.
DR   InterPro; IPR031717; KGD_C.
DR   InterPro; IPR029061; THDP-binding.
DR   InterPro; IPR005475; Transketolase-like_Pyr-bd.
DR   PANTHER; PTHR23152; PTHR23152; 1.
DR   Pfam; PF00198; 2-oxoacid_dh; 1.
DR   Pfam; PF16078; 2-oxogl_dehyd_N; 1.
DR   Pfam; PF00676; E1_dh; 1.
DR   Pfam; PF16870; OxoGdeHyase_C; 1.
DR   Pfam; PF02779; Transket_pyr; 1.
DR   PIRSF; PIRSF000157; Oxoglu_dh_E1; 1.
DR   SMART; SM00861; Transket_pyr; 1.
DR   SUPFAM; SSF52518; SSF52518; 2.
DR   TIGRFAMs; TIGR00239; 2oxo_dh_E1; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000060513}.
FT   DOMAIN      924   1117       Transket_pyr. {ECO:0000259|SMART:
FT                                SM00861}.
SQ   SEQUENCE   1272 AA;  139429 MW;  D454E572C66CC4F2 CRC64;
     MSSQSPSNSS ISTDQAGQGQ NPAAAFGANE WLVDEIYQQY LQDPNSVDRA WWDFFADYKP
     GAAATADAPA AGAKQTQSDA AAVTAAAPAP AAAPARPETP AQPAPAAPAP AAPAAPAAQA
     PAPAKAAPAA APAKPAAKPA PAAKADGSQA EGPEFVTLRG PAAAVAKNMN ASLELPTATS
     VRAVPVKLLF DNRIVINNHL KRARGGKISF THLIGYAMVQ AIKAMPSMNW SFAEKDGKPT
     LVKPDHVNFG LAIDLVKPNG DRQLVVAGIK KAETLNFFEF WQAYEDIVRR ARTNKLTMDD
     FTGVTVSLTN PGGLGTVHSV PRLMPGQSVI MGVGSMDYPA EFQGTSQDTL NKLGISKVMT
     LTSTYDHRVI QGAASGEFLR IVANFLLGEE GFYDEIFESL RIPYEPVRWL KDIDASHDDD
     VTKAARVFEL IHSYRVRGHV MADTDPLEYR QRKHPDLDIT EHGLTLWDLE REFAVGGFAG
     KSMMKLRDIL GVLRESYCRT TGIEFMHIQD PKQRKWLQDR VERAASKPER EEQLRILRRL
     NAAEAFEIFL QTKYVGQKRF SLEGGESVIP LLDAVIDSAA ESRLDEVVIG MAHRGRLNVL
     ANIVGKSYAQ IFREFEGNLD PKSMHGSGDV KYHLGAEGTF TGLDGEQIKV SLVANPSHLE
     AVDPVLEGVS RAKQDVINKG GTDFTVLPIA LHGDAAFAGQ GVVAETLNMS QLRGYRTGGT
     VHVVINNQVG FTAAPESSRS SMYATDVARM IEAPIFHVNG DDPEAVVRVA RLAFEFRQAF
     NKDVVIDLIC YRRRGHNEGD NPSFTNPQMY NLIDKKRSVR KLYTESLIGR GDITLEEAEQ
     SLQDFQGQLE KVFAEVREAT SHPAPAHVPD VEAEFPVAVN TAVSQEVVKR IAESQVNIPD
     NITVHPRLMP QMQRRAASVE DGTIDWGMGE TLAIGSLLME GTPVRLSGQD TRRGTFGQRH
     AVLVDQETGE DYTPLLYLSE DQARYNVYDS LLSEYAAMGF EYGYSLARPD ALVMWEAQFG
     DFVNGAQTVV DEFISSAEQK WGQHSGVTLL LPHGYEGQGP DHSSARPERF LQMCAQDNMT
     VAMPTLPSNY FHLLRWQVHN PHHKPLIVFT PKSMLRLKAA ASKVEEFTTG GFRPVIGDDS
     VDPNAVRKVV FCSGKVYYDL EAEREKRGVT DTAIIRLERL YPLPGAEVQA EIAKYPNAEK
     YLWTQEEPAN QGAWPFIALN LIDHLDLAVG ADIPHGERLR RISRPHSSSP AVGSAKRHQA
     EQQQLVNEVF DA
//
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