ID A0A0M4N1B4_BIFLN Unreviewed; 246 AA.
AC A0A0M4N1B4; E5XX59;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 58.
DE RecName: Full=2,3-bisphosphoglycerate-dependent phosphoglycerate mutase {ECO:0000256|HAMAP-Rule:MF_01039, ECO:0000256|RuleBase:RU004512};
DE Short=BPG-dependent PGAM {ECO:0000256|HAMAP-Rule:MF_01039};
DE Short=PGAM {ECO:0000256|HAMAP-Rule:MF_01039};
DE Short=Phosphoglyceromutase {ECO:0000256|HAMAP-Rule:MF_01039};
DE Short=dPGM {ECO:0000256|HAMAP-Rule:MF_01039};
DE EC=5.4.2.11 {ECO:0000256|HAMAP-Rule:MF_01039, ECO:0000256|RuleBase:RU004512};
GN Name=gpmA {ECO:0000256|HAMAP-Rule:MF_01039,
GN ECO:0000313|EMBL:ALE36907.1};
GN ORFNames=APC1464_1480 {ECO:0000313|EMBL:PKD09835.1}, APC1468_1660
GN {ECO:0000313|EMBL:PKD03122.1}, APC1503_1718
GN {ECO:0000313|EMBL:PKC87512.1}, B5779_1740
GN {ECO:0000313|EMBL:OQM71470.1}, B5780_1748
GN {ECO:0000313|EMBL:OQM59269.1}, B5781_1788
GN {ECO:0000313|EMBL:OQM50199.1}, B5U78_02270
GN {ECO:0000313|EMBL:ROV52799.1}, BBG7_1720
GN {ECO:0000313|EMBL:ALE36907.1}, CE161_03985
GN {ECO:0000313|EMBL:RDX18684.1}, CE169_06095
GN {ECO:0000313|EMBL:RDX08327.1}, CWE05_06485
GN {ECO:0000313|EMBL:PWH08792.1}, CYJ39_04610
GN {ECO:0000313|EMBL:PKY77246.1}, DPC6316_1614
GN {ECO:0000313|EMBL:PKC83774.1}, DPC6317_1635
GN {ECO:0000313|EMBL:PKC82316.1}, DWV47_05925
GN {ECO:0000313|EMBL:RGW83251.1}, DWV59_00745
GN {ECO:0000313|EMBL:RGW66046.1}, DWZ73_05690
GN {ECO:0000313|EMBL:RHM28611.1}, DXC63_11145
GN {ECO:0000313|EMBL:RGL45371.1}, GBB40_02185
GN {ECO:0000313|EMBL:KAB7396435.1}, GBB63_06930
GN {ECO:0000313|EMBL:KAB7358505.1}, GBB65_00040
GN {ECO:0000313|EMBL:KAB7323909.1}, GBB73_07105
GN {ECO:0000313|EMBL:KAB7336856.1}, GBC43_08420
GN {ECO:0000313|EMBL:KAB7234844.1}, GBC45_05015
GN {ECO:0000313|EMBL:KAB7203652.1}, GBC97_01955
GN {ECO:0000313|EMBL:KAB7137222.1}, GBI83_07620
GN {ECO:0000313|EMBL:KAB7072265.1}, GBI87_07925
GN {ECO:0000313|EMBL:KAB7056702.1}, GBJ98_01655
GN {ECO:0000313|EMBL:KAB6914359.1}, GBJ99_01195
GN {ECO:0000313|EMBL:KAB6911937.1}, GBK06_01745
GN {ECO:0000313|EMBL:KAB6920326.1}, GBK08_02045
GN {ECO:0000313|EMBL:KAB6838751.1}, GS08_08665
GN {ECO:0000313|EMBL:AIF91169.1}, GT999_05085
GN {ECO:0000313|EMBL:MZR88690.1}, GUA24_02925
GN {ECO:0000313|EMBL:MZU07997.1}, HMPREF0177_00562
GN {ECO:0000313|EMBL:EFV37779.1}, HMPREF3231_00149
GN {ECO:0000313|EMBL:KWZ96025.1}, SAMN04489748_0183
GN {ECO:0000313|EMBL:SEB29770.1};
OS Bifidobacterium longum.
OC Bacteria; Actinomycetota; Actinomycetes; Bifidobacteriales;
OC Bifidobacteriaceae; Bifidobacterium.
OX NCBI_TaxID=216816 {ECO:0000313|EMBL:ALE36907.1, ECO:0000313|Proteomes:UP000055147};
RN [1] {ECO:0000313|EMBL:EFV37779.1, ECO:0000313|Proteomes:UP000003025}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=12_1_47BFAA {ECO:0000313|EMBL:EFV37779.1,
RC ECO:0000313|Proteomes:UP000003025};
RG The Broad Institute Genome Sequencing Platform;
RA Ward D., Earl A., Feldgarden M., Young S.K., Gargeya S., Zeng Q.,
RA Alvarado L., Berlin A., Bochicchio J., Chapman S.B., Chen Z., Freedman E.,
RA Gellesch M., Goldberg J., Griggs A., Gujja S., Heilman E., Heiman D.,
RA Howarth C., Mehta T., Neiman D., Pearson M., Roberts A., Saif S., Shea T.,
RA Shenoy N., Sisk P., Stolte C., Sykes S., White J., Yandava C.,
RA Allen-Vercoe E., Ambrose C., Strauss J., McDonald J., Haas B., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Bifidobacterium sp. strain 12_1_47BFAA.";
RL Submitted (OCT-2010) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:AIF91169.1, ECO:0000313|Proteomes:UP000028505}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BXY01 {ECO:0000313|EMBL:AIF91169.1,
RC ECO:0000313|Proteomes:UP000028505};
RA Zhao X.;
RL Submitted (JUN-2014) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:AIF91169.1, ECO:0000313|Proteomes:UP000028505}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BXY01 {ECO:0000313|EMBL:AIF91169.1,
RC ECO:0000313|Proteomes:UP000028505};
RA Yuan J., Wei X., Li H., Liu W., Wang X.;
RT "Bifidobacterium longum genome.";
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|EMBL:ALE36907.1, ECO:0000313|Proteomes:UP000055147}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BG7 {ECO:0000313|EMBL:ALE36907.1,
RC ECO:0000313|Proteomes:UP000055147};
RA Kwon S.-K., Kim J.F.;
RT "Complete genome sequence of Bifidobacterium longum BG7.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
RN [5] {ECO:0000313|EMBL:KWZ96025.1, ECO:0000313|Proteomes:UP000070323}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CMW7750 {ECO:0000313|EMBL:KWZ96025.1,
RC ECO:0000313|Proteomes:UP000070323};
RA Oliw E.H.;
RL Submitted (JAN-2016) to the EMBL/GenBank/DDBJ databases.
RN [6] {ECO:0000313|EMBL:SEB29770.1, ECO:0000313|Proteomes:UP000182842}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 20219 {ECO:0000313|EMBL:SEB29770.1,
RC ECO:0000313|Proteomes:UP000182842};
RA Varghese N., Submissions S.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
RN [7] {ECO:0000313|Proteomes:UP000256339, ECO:0000313|Proteomes:UP000257074}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=239-2 {ECO:0000313|EMBL:RDX18684.1,
RC ECO:0000313|Proteomes:UP000256339}, and N6D05
RC {ECO:0000313|EMBL:RDX08327.1, ECO:0000313|Proteomes:UP000257074};
RX PubMed=28552417; DOI=10.1016/j.anaerobe.2017.05.012;
RA Freitas A.C., Hill J.E.;
RT "Quantification, isolation and characterization of Bifidobacterium from the
RT vaginal microbiomes of reproductive aged women.";
RL Anaerobe 47:145-156(2017).
RN [8] {ECO:0000313|Proteomes:UP000192289, ECO:0000313|Proteomes:UP000192302}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1886B {ECO:0000313|EMBL:OQM71470.1,
RC ECO:0000313|Proteomes:UP000192607}, 1897B
RC {ECO:0000313|EMBL:OQM59269.1, ECO:0000313|Proteomes:UP000192302}, and
RC 1898B {ECO:0000313|EMBL:OQM50199.1,
RC ECO:0000313|Proteomes:UP000192289};
RA Lugli G.A., Duranti S., Milani C., Mancabelli L.;
RT "Maternal inheritance of bifidobacteria.";
RL Submitted (MAR-2017) to the EMBL/GenBank/DDBJ databases.
RN [9] {ECO:0000313|EMBL:PWH08792.1, ECO:0000313|Proteomes:UP000245582}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UMA026 {ECO:0000313|EMBL:PWH08792.1,
RC ECO:0000313|Proteomes:UP000245582};
RA Albert K., Sela D.A.;
RT "Draft genome sequence of Bifidobacterium longum UMA026, isolated from
RT Holstein dairy cow feces.";
RL Submitted (NOV-2017) to the EMBL/GenBank/DDBJ databases.
RN [10] {ECO:0000313|Proteomes:UP000232456, ECO:0000313|Proteomes:UP000232515}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=APC1464 {ECO:0000313|EMBL:PKD09835.1,
RC ECO:0000313|Proteomes:UP000232456}, APC1468
RC {ECO:0000313|EMBL:PKD03122.1, ECO:0000313|Proteomes:UP000232515},
RC APC1503 {ECO:0000313|EMBL:PKC87512.1,
RC ECO:0000313|Proteomes:UP000232654}, DPC6316
RC {ECO:0000313|EMBL:PKC83774.1, ECO:0000313|Proteomes:UP000232554}, and
RC DPC6317 {ECO:0000313|EMBL:PKC82316.1,
RC ECO:0000313|Proteomes:UP000232637};
RA Arboleya S.;
RT "Bifidobacterium longum APC/DPC strains.";
RL Submitted (DEC-2017) to the EMBL/GenBank/DDBJ databases.
RN [11] {ECO:0000313|EMBL:PKY77246.1, ECO:0000313|Proteomes:UP000234964}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UMB0788 {ECO:0000313|EMBL:PKY77246.1,
RC ECO:0000313|Proteomes:UP000234964};
RA Thomas-White K., Wolfe A.J.;
RT "Phylogenetic diversity of female urinary microbiome.";
RL Submitted (DEC-2017) to the EMBL/GenBank/DDBJ databases.
RN [12] {ECO:0000313|Proteomes:UP000261288, ECO:0000313|Proteomes:UP000265775}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AF08-2 {ECO:0000313|EMBL:RGW83251.1,
RC ECO:0000313|Proteomes:UP000284732}, AF11-12
RC {ECO:0000313|EMBL:RGW66046.1, ECO:0000313|Proteomes:UP000265775},
RC AF35-13AC {ECO:0000313|EMBL:RHM28611.1,
RC ECO:0000313|Proteomes:UP000265840}, and TF06-45A
RC {ECO:0000313|EMBL:RGL45371.1, ECO:0000313|Proteomes:UP000261288};
RA Zou Y., Xue W., Luo G.;
RT "A genome reference for cultivated species of the human gut microbiota.";
RL Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
RN [13] {ECO:0000313|EMBL:ROV52799.1, ECO:0000313|Proteomes:UP000273962}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ICIS-505 {ECO:0000313|EMBL:ROV52799.1,
RC ECO:0000313|Proteomes:UP000273962};
RA Andryuschenko S.V., Ivanova E.V., Perunova N.B., Semenovykh T.A.,
RA Bukharin O.V.;
RT "Draft genome sequence of some Bifidobacteria gut isolates.";
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
RN [14] {ECO:0000313|Proteomes:UP000429224, ECO:0000313|Proteomes:UP000430971}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BIOML-A118 {ECO:0000313|EMBL:KAB7234844.1,
RC ECO:0000313|Proteomes:UP000460333}, BIOML-A136
RC {ECO:0000313|EMBL:KAB7203652.1, ECO:0000313|Proteomes:UP000476628},
RC BIOML-A166 {ECO:0000313|EMBL:KAB7137222.1,
RC ECO:0000313|Proteomes:UP000461165}, BIOML-A201
RC {ECO:0000313|EMBL:KAB7072265.1, ECO:0000313|Proteomes:UP000432196},
RC BIOML-A210 {ECO:0000313|EMBL:KAB7056702.1,
RC ECO:0000313|Proteomes:UP000467387}, BIOML-A283
RC {ECO:0000313|EMBL:KAB6914359.1, ECO:0000313|Proteomes:UP000481350},
RC BIOML-A284 {ECO:0000313|EMBL:KAB6920326.1,
RC ECO:0000313|Proteomes:UP000491334}, BIOML-A286
RC {ECO:0000313|EMBL:KAB6911937.1, ECO:0000313|Proteomes:UP000429224},
RC BIOML-A320 {ECO:0000313|EMBL:KAB6838751.1,
RC ECO:0000313|Proteomes:UP000478746}, BIOML-A37
RC {ECO:0000313|EMBL:KAB7396435.1, ECO:0000313|Proteomes:UP000468842},
RC BIOML-A395 {ECO:0000313|EMBL:MZR88690.1,
RC ECO:0000313|Proteomes:UP000466472}, BIOML-A409
RC {ECO:0000313|EMBL:MZU07997.1}, BIOML-A55
RC {ECO:0000313|EMBL:KAB7358505.1, ECO:0000313|Proteomes:UP000460881},
RC BIOML-A65 {ECO:0000313|EMBL:KAB7336856.1,
RC ECO:0000313|Proteomes:UP000430971}, and BIOML-A75
RC {ECO:0000313|EMBL:KAB7323909.1, ECO:0000313|Proteomes:UP000451234};
RX PubMed=31477907; DOI=.1038/s41591-019-0559-3;
RA Poyet M., Groussin M., Gibbons S.M., Avila-Pacheco J., Jiang X.,
RA Kearney S.M., Perrotta A.R., Berdy B., Zhao S., Lieberman T.D.,
RA Swanson P.K., Smith M., Roesemann S., Alexander J.E., Rich S.A., Livny J.,
RA Vlamakis H., Clish C., Bullock K., Deik A., Scott J., Pierce K.A.,
RA Xavier R.J., Alm E.J.;
RT "A library of human gut bacterial isolates paired with longitudinal
RT multiomics data enables mechanistic microbiome research.";
RL Nat. Med. 25:1442-1452(2019).
CC -!- FUNCTION: Catalyzes the interconversion of 2-phosphoglycerate and 3-
CC phosphoglycerate. {ECO:0000256|HAMAP-Rule:MF_01039,
CC ECO:0000256|RuleBase:RU004512}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=(2R)-2-phosphoglycerate = (2R)-3-phosphoglycerate;
CC Xref=Rhea:RHEA:15901, ChEBI:CHEBI:58272, ChEBI:CHEBI:58289;
CC EC=5.4.2.11; Evidence={ECO:0000256|ARBA:ARBA00000380,
CC ECO:0000256|HAMAP-Rule:MF_01039, ECO:0000256|RuleBase:RU004512};
CC -!- PATHWAY: Carbohydrate degradation; glycolysis; pyruvate from D-
CC glyceraldehyde 3-phosphate: step 3/5. {ECO:0000256|HAMAP-Rule:MF_01039,
CC ECO:0000256|RuleBase:RU004512}.
CC -!- SIMILARITY: Belongs to the phosphoglycerate mutase family. BPG-
CC dependent PGAM subfamily. {ECO:0000256|ARBA:ARBA00006717,
CC ECO:0000256|HAMAP-Rule:MF_01039}.
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DR EMBL; CP008885; AIF91169.1; -; Genomic_DNA.
DR EMBL; CP010453; ALE36907.1; -; Genomic_DNA.
DR EMBL; ADCN01000014; EFV37779.1; -; Genomic_DNA.
DR EMBL; WEAY01000003; KAB6838751.1; -; Genomic_DNA.
DR EMBL; WDZR01000002; KAB6911937.1; -; Genomic_DNA.
DR EMBL; WDZO01000002; KAB6914359.1; -; Genomic_DNA.
DR EMBL; WDZP01000002; KAB6920326.1; -; Genomic_DNA.
DR EMBL; WDWU01000010; KAB7056702.1; -; Genomic_DNA.
DR EMBL; WDWL01000009; KAB7072265.1; -; Genomic_DNA.
DR EMBL; WDVF01000003; KAB7137222.1; -; Genomic_DNA.
DR EMBL; WDUB01000005; KAB7203652.1; -; Genomic_DNA.
DR EMBL; WDTJ01000013; KAB7234844.1; -; Genomic_DNA.
DR EMBL; WDRV01000001; KAB7323909.1; -; Genomic_DNA.
DR EMBL; WDRM01000016; KAB7336856.1; -; Genomic_DNA.
DR EMBL; WDRC01000016; KAB7358505.1; -; Genomic_DNA.
DR EMBL; WDQK01000003; KAB7396435.1; -; Genomic_DNA.
DR EMBL; LRPQ01000004; KWZ96025.1; -; Genomic_DNA.
DR EMBL; WXEF01000008; MZR88690.1; -; Genomic_DNA.
DR EMBL; WXDR01000003; MZU07997.1; -; Genomic_DNA.
DR EMBL; NAQB01000022; OQM50199.1; -; Genomic_DNA.
DR EMBL; NAQC01000021; OQM59269.1; -; Genomic_DNA.
DR EMBL; NAQL01000015; OQM71470.1; -; Genomic_DNA.
DR EMBL; PJDQ01000011; PKC82316.1; -; Genomic_DNA.
DR EMBL; PJDR01000017; PKC83774.1; -; Genomic_DNA.
DR EMBL; PJDT01000024; PKC87512.1; -; Genomic_DNA.
DR EMBL; PJEB01000029; PKD03122.1; -; Genomic_DNA.
DR EMBL; PJEE01000011; PKD09835.1; -; Genomic_DNA.
DR EMBL; PKGP01000003; PKY77246.1; -; Genomic_DNA.
DR EMBL; PHUM01000006; PWH08792.1; -; Genomic_DNA.
DR EMBL; NJNR01000028; RDX08327.1; -; Genomic_DNA.
DR EMBL; NJNZ01000017; RDX18684.1; -; Genomic_DNA.
DR EMBL; QSRZ01000013; RGL45371.1; -; Genomic_DNA.
DR EMBL; QSAR01000001; RGW66046.1; -; Genomic_DNA.
DR EMBL; QSAY01000003; RGW83251.1; -; Genomic_DNA.
DR EMBL; QRPR01000003; RHM28611.1; -; Genomic_DNA.
DR EMBL; RJZF01000002; ROV52799.1; -; Genomic_DNA.
DR EMBL; FNRW01000001; SEB29770.1; -; Genomic_DNA.
DR RefSeq; WP_007052347.1; NZ_WQQG01000005.1.
DR GeneID; 69578825; -.
DR KEGG; blx:GS08_08665; -.
DR PATRIC; fig|216816.111.peg.1762; -.
DR eggNOG; COG0588; Bacteria.
DR HOGENOM; CLU_033323_1_1_11; -.
DR OMA; RMLPYWY; -.
DR UniPathway; UPA00109; UER00186.
DR Proteomes; UP000003025; Unassembled WGS sequence.
DR Proteomes; UP000028505; Chromosome.
DR Proteomes; UP000055147; Chromosome.
DR Proteomes; UP000070323; Unassembled WGS sequence.
DR Proteomes; UP000182842; Unassembled WGS sequence.
DR Proteomes; UP000192289; Unassembled WGS sequence.
DR Proteomes; UP000192302; Unassembled WGS sequence.
DR Proteomes; UP000192607; Unassembled WGS sequence.
DR Proteomes; UP000232456; Unassembled WGS sequence.
DR Proteomes; UP000232515; Unassembled WGS sequence.
DR Proteomes; UP000232554; Unassembled WGS sequence.
DR Proteomes; UP000232637; Unassembled WGS sequence.
DR Proteomes; UP000232654; Unassembled WGS sequence.
DR Proteomes; UP000234964; Unassembled WGS sequence.
DR Proteomes; UP000245582; Unassembled WGS sequence.
DR Proteomes; UP000256339; Unassembled WGS sequence.
DR Proteomes; UP000257074; Unassembled WGS sequence.
DR Proteomes; UP000261288; Unassembled WGS sequence.
DR Proteomes; UP000265775; Unassembled WGS sequence.
DR Proteomes; UP000265840; Unassembled WGS sequence.
DR Proteomes; UP000273962; Unassembled WGS sequence.
DR Proteomes; UP000284732; Unassembled WGS sequence.
DR Proteomes; UP000429224; Unassembled WGS sequence.
DR Proteomes; UP000430971; Unassembled WGS sequence.
DR Proteomes; UP000432196; Unassembled WGS sequence.
DR Proteomes; UP000451234; Unassembled WGS sequence.
DR Proteomes; UP000460333; Unassembled WGS sequence.
DR Proteomes; UP000460881; Unassembled WGS sequence.
DR Proteomes; UP000461165; Unassembled WGS sequence.
DR Proteomes; UP000466472; Unassembled WGS sequence.
DR Proteomes; UP000467387; Unassembled WGS sequence.
DR Proteomes; UP000468842; Unassembled WGS sequence.
DR Proteomes; UP000476628; Unassembled WGS sequence.
DR Proteomes; UP000478746; Unassembled WGS sequence.
DR Proteomes; UP000481350; Unassembled WGS sequence.
DR Proteomes; UP000491334; Unassembled WGS sequence.
DR Proteomes; UP000638311; Unassembled WGS sequence.
DR GO; GO:0046538; F:2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006094; P:gluconeogenesis; IEA:UniProtKB-UniRule.
DR GO; GO:0006096; P:glycolytic process; IEA:UniProtKB-UniRule.
DR CDD; cd07067; HP_PGM_like; 1.
DR Gene3D; 3.40.50.1240; Phosphoglycerate mutase-like; 1.
DR HAMAP; MF_01039; PGAM_GpmA; 1.
DR InterPro; IPR013078; His_Pase_superF_clade-1.
DR InterPro; IPR029033; His_PPase_superfam.
DR InterPro; IPR001345; PG/BPGM_mutase_AS.
DR InterPro; IPR005952; Phosphogly_mut1.
DR NCBIfam; TIGR01258; pgm_1; 1.
DR PANTHER; PTHR11931; PHOSPHOGLYCERATE MUTASE; 1.
DR PANTHER; PTHR11931:SF0; PHOSPHOGLYCERATE MUTASE; 1.
DR Pfam; PF00300; His_Phos_1; 1.
DR PIRSF; PIRSF000709; 6PFK_2-Ptase; 2.
DR SMART; SM00855; PGAM; 1.
DR SUPFAM; SSF53254; Phosphoglycerate mutase-like; 1.
DR PROSITE; PS00175; PG_MUTASE; 1.
PE 3: Inferred from homology;
KW Gluconeogenesis {ECO:0000256|HAMAP-Rule:MF_01039};
KW Glycolysis {ECO:0000256|ARBA:ARBA00023152, ECO:0000256|HAMAP-
KW Rule:MF_01039};
KW Isomerase {ECO:0000256|ARBA:ARBA00023235, ECO:0000256|HAMAP-Rule:MF_01039}.
FT ACT_SITE 10
FT /note="Tele-phosphohistidine intermediate"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01039,
FT ECO:0000256|PIRSR:PIRSR613078-1"
FT ACT_SITE 88
FT /note="Proton donor/acceptor"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01039,
FT ECO:0000256|PIRSR:PIRSR613078-1"
FT BINDING 9..16
FT /ligand="substrate"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01039,
FT ECO:0000256|PIRSR:PIRSR613078-2"
FT BINDING 22..23
FT /ligand="substrate"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01039,
FT ECO:0000256|PIRSR:PIRSR613078-2"
FT BINDING 61
FT /ligand="substrate"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01039,
FT ECO:0000256|PIRSR:PIRSR613078-2"
FT BINDING 88..91
FT /ligand="substrate"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01039,
FT ECO:0000256|PIRSR:PIRSR613078-2"
FT BINDING 99
FT /ligand="substrate"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01039,
FT ECO:0000256|PIRSR:PIRSR613078-2"
FT BINDING 115..116
FT /ligand="substrate"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01039,
FT ECO:0000256|PIRSR:PIRSR613078-2"
FT BINDING 181..182
FT /ligand="substrate"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01039,
FT ECO:0000256|PIRSR:PIRSR613078-2"
FT SITE 180
FT /note="Transition state stabilizer"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01039,
FT ECO:0000256|PIRSR:PIRSR613078-3"
SQ SEQUENCE 246 AA; 27605 MW; 4C18E0BEC1796407 CRC64;
MTYKLVLLRH GQSAWNKTNQ FTGWVDVPLT EQGEAEAKRG GELLKEKNVL PDIVFTSLLR
RAINTANIAL DAADRLWIPV QRDWRLNERH YGALQGKNKT EIREEYGDEK FMLWRRSYAT
PPPEIDPNDQ YAQNNDPRYA GDPVPEAECL ANVVERVKPY FESAIEPELK AGKTVLIAAH
GNSLRAIVKM LDNLSEEEIA KVNIPTAIPL LYELDENFKP IKPRGEYLDP EAAAAGAAAV
AAQGQK
//
