ID   A0A0P0DPH1_SPHMC        Unreviewed;       476 AA.
AC   A0A0P0DPH1;
DT   20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT   20-JAN-2016, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   SubName: Full=Aldehyde dehydrogenase {ECO:0000313|EMBL:ALJ16153.1};
GN   ORFNames=LH19_25020 {ECO:0000313|EMBL:ALJ16153.1};
OS   Sphingopyxis macrogoltabida (Sphingomonas macrogoltabidus).
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC   Sphingomonadaceae; Sphingopyxis.
OX   NCBI_TaxID=33050 {ECO:0000313|EMBL:ALJ16153.1, ECO:0000313|Proteomes:UP000062472};
RN   [1] {ECO:0000313|EMBL:ALJ16153.1, ECO:0000313|Proteomes:UP000062472}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=203 {ECO:0000313|EMBL:ALJ16153.1,
RC   ECO:0000313|Proteomes:UP000062472};
RA   Ohtsubo Y., Nagata Y., Numata M., Tsuchikane K., Hosoyama A., Yamazoe A.,
RA   Tsuda M., Fujita N., Kawai F.;
RT   "Complete genome sequence of a mutant derivative (NBRC15033) of
RT   polyethylene glycol-degrading strain Sphingopyxis macrogoltabidus strain
RT   203.";
RL   Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the aldehyde dehydrogenase family.
CC       {ECO:0000256|RuleBase:RU003345}.
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DR   EMBL; CP009429; ALJ16153.1; -; Genomic_DNA.
DR   RefSeq; WP_054732486.1; NZ_CP013344.1.
DR   AlphaFoldDB; A0A0P0DPH1; -.
DR   STRING; 33050.AN936_21755; -.
DR   KEGG; smaz:LH19_25020; -.
DR   PATRIC; fig|33050.6.peg.5094; -.
DR   OrthoDB; 9761688at2; -.
DR   Proteomes; UP000062472; Chromosome.
DR   GO; GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR   CDD; cd07097; ALDH_KGSADH-YcbD; 1.
DR   InterPro; IPR016161; Ald_DH/histidinol_DH.
DR   InterPro; IPR016163; Ald_DH_C.
DR   InterPro; IPR016160; Ald_DH_CS_CYS.
DR   InterPro; IPR029510; Ald_DH_CS_GLU.
DR   InterPro; IPR016162; Ald_DH_N.
DR   InterPro; IPR015590; Aldehyde_DH_dom.
DR   PANTHER; PTHR11699:SF211; ALDEHYDE DEHYDROGENASE FAMILY 16 MEMBER A1; 1.
DR   PANTHER; PTHR11699; ALDEHYDE DEHYDROGENASE-RELATED; 1.
DR   Pfam; PF00171; Aldedh; 1.
DR   SUPFAM; SSF53720; ALDH-like; 1.
DR   PROSITE; PS00070; ALDEHYDE_DEHYDR_CYS; 1.
DR   PROSITE; PS00687; ALDEHYDE_DEHYDR_GLU; 1.
PE   3: Inferred from homology;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW   ECO:0000256|RuleBase:RU003345}.
FT   DOMAIN          11..472
FT                   /note="Aldehyde dehydrogenase"
FT                   /evidence="ECO:0000259|Pfam:PF00171"
FT   ACT_SITE        245
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU10007"
SQ   SEQUENCE   476 AA;  49849 MW;  E784E19A9EDAF297 CRC64;
     MKLSHLIDGE WVASDASAAS INPSNTEEVV AHYPLGGAAE VDAAVAAARR AFGGWAAASP
     EVRSDLLDRV GSTVMARAAE LGELLAREEG KTRAEATGEV MRAARIFKYF AGEALRRHGR
     TLESTRPGLD VEVWREAVGV VGLITPWNFP IAIPAWKAAP ALAFGNTVVL KPAQHTPAVA
     HALAAIIAEC GAPAGVFNLV LGQGQVGAAV AAHPGIDAIS FTGSQAVGGK VAQAAVARGA
     RVQLEMGGKN PLVVLADANL DRAVAIALDG GFFQTGQRCT ASSRVIVEDA VHDRFVAALA
     ERASALRVGA ALDPATEVGP ASNQSQYEQN LRYIDIATAD GGRLVTGGDA LRLDTPGYYM
     RPALIADTAP DMRINREEVF GPLVSTVRVK DYDEALAVAN QGDFGLSAGI VTTSLARARH
     FRRNVRAGMV MVNLPTAGVD YHVPFGGTRG SSYGPREQGF AAVDFYTQMK TVYVGD
//