GenomeNet

Database: UniProt/TrEMBL
Entry: A0A0P0FQC8_BACT4
LinkDB: A0A0P0FQC8_BACT4
Original site: A0A0P0FQC8_BACT4 
ID   A0A0P0FQC8_BACT4        Unreviewed;       481 AA.
AC   A0A0P0FQC8;
DT   20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT   20-JAN-2016, sequence version 1.
DT   27-SEP-2017, entry version 13.
DE   SubName: Full=Alpha-amylase {ECO:0000313|EMBL:ALJ42831.1};
DE            EC=3.2.1.1 {ECO:0000313|EMBL:ALJ42831.1};
GN   ORFNames=BJP75_17805 {ECO:0000313|EMBL:OGX99304.1}, Btheta7330_03297
GN   {ECO:0000313|EMBL:ALJ42831.1};
OS   Bacteroides thetaiotaomicron.
OC   Bacteria; Bacteroidetes; Bacteroidia; Bacteroidales; Bacteroidaceae;
OC   Bacteroides.
OX   NCBI_TaxID=818 {ECO:0000313|EMBL:ALJ42831.1, ECO:0000313|Proteomes:UP000066931};
RN   [1] {ECO:0000313|EMBL:ALJ42831.1, ECO:0000313|Proteomes:UP000066931}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=7330 {ECO:0000313|EMBL:ALJ42831.1,
RC   ECO:0000313|Proteomes:UP000066931};
RX   PubMed=26430127;
RA   Wu M., McNulty N.P., Rodionov D.A., Khoroshkin M.S., Griffin N.W.,
RA   Cheng J., Latreille P., Kerstetter R.A., Terrapon N., Henrissat B.,
RA   Osterman A.L., Gordon J.I.;
RT   "Genetic determinants of in vivo fitness and diet responsiveness in
RT   multiple human gut Bacteroides.";
RL   Science 350:AAC5992-AAC5992(2015).
RN   [2] {ECO:0000313|EMBL:OGX99304.1, ECO:0000313|Proteomes:UP000178402}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=14-106904-2 {ECO:0000313|EMBL:OGX99304.1,
RC   ECO:0000313|Proteomes:UP000178402};
RA   Sydenham T.V., Kaallman O., Giske C.G., Kemp M., Justesen U.S.;
RT   "A unique case of metronidazole resistant Bacteroides fragilis and B.
RT   thetaiotaomicron from one patient; first report of nimJ metronidazole
RT   resistance gene in B. thetaiotaomicron.";
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; CP012937; ALJ42831.1; -; Genomic_DNA.
DR   EMBL; MKXM01000023; OGX99304.1; -; Genomic_DNA.
DR   RefSeq; WP_008766792.1; NZ_MKXM01000023.1.
DR   EnsemblBacteria; ALJ42831; ALJ42831; Btheta7330_03297.
DR   GeneID; 31617750; -.
DR   KEGG; btho:Btheta7330_03297; -.
DR   PATRIC; fig|818.23.peg.3390; -.
DR   KO; K01176; -.
DR   Proteomes; UP000066931; Chromosome.
DR   Proteomes; UP000178402; Unassembled WGS sequence.
DR   GO; GO:0004556; F:alpha-amylase activity; IEA:UniProtKB-EC.
DR   GO; GO:0103025; F:alpha-amylase activity (releasing maltohexaose); IEA:UniProtKB-EC.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   InterPro; IPR013776; A-amylase_thermo.
DR   InterPro; IPR006047; Glyco_hydro_13_cat_dom.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   Pfam; PF00128; Alpha-amylase; 1.
DR   PIRSF; PIRSF001021; Alph-amls_thrmst; 1.
DR   SMART; SM00642; Aamy; 1.
DR   SUPFAM; SSF51445; SSF51445; 1.
PE   4: Predicted;
KW   Calcium {ECO:0000256|PIRSR:PIRSR001021-2};
KW   Complete proteome {ECO:0000313|Proteomes:UP000066931,
KW   ECO:0000313|Proteomes:UP000178402};
KW   Glycosidase {ECO:0000313|EMBL:ALJ42831.1};
KW   Hydrolase {ECO:0000313|EMBL:ALJ42831.1};
KW   Metal-binding {ECO:0000256|PIRSR:PIRSR001021-2}.
FT   DOMAIN        4    410       Aamy. {ECO:0000259|SMART:SM00642}.
FT   ACT_SITE    232    232       Nucleophile. {ECO:0000256|PIRSR:
FT                                PIRSR001021-1}.
FT   ACT_SITE    262    262       Proton donor. {ECO:0000256|PIRSR:
FT                                PIRSR001021-1}.
FT   METAL       103    103       Calcium 1. {ECO:0000256|PIRSR:
FT                                PIRSR001021-2}.
FT   METAL       182    182       Calcium 2; via carbonyl oxygen.
FT                                {ECO:0000256|PIRSR:PIRSR001021-2}.
FT   METAL       195    195       Calcium 1. {ECO:0000256|PIRSR:
FT                                PIRSR001021-2}.
FT   METAL       201    201       Calcium 1. {ECO:0000256|PIRSR:
FT                                PIRSR001021-2}.
FT   METAL       203    203       Calcium 2. {ECO:0000256|PIRSR:
FT                                PIRSR001021-2}.
FT   METAL       236    236       Calcium 1; via carbonyl oxygen.
FT                                {ECO:0000256|PIRSR:PIRSR001021-2}.
SQ   SEQUENCE   481 AA;  55272 MW;  B6BF20C6F0C90C90 CRC64;
     MENGVMMQYF EWHLPNDGKL WKQIKEDALH LHDIGVTAVW IPPAYKADEQ QDEGYATYDL
     YDLGEFDQKG TIRTKYGTKD ELKKMIDELH KYHIAVYLDV VLNHKAGGDF TEKFMVVEVD
     PKERTKALGE PFEIQGWTGY SFHGRKDKHS DFKWHWYHFS GTGFDDAQKR SGVFQIQGEG
     KAWSEGVDSE NGNYDFLLCN DIDLDHPEVV SELNRWGKWV SNELNLDGMR LDAIKHMKDQ
     FVAQFLDAVR SERGNDFYAV GEYWNGDLEA LDAYIEAVGH KVNLFDVPLH YNMFQASQEG
     KDYDLRDILK DTLVEHHPDL AVTIVDNHDT QRGSSLESNV GDWFKPLAYG LILLMKEGYP
     CLFYGDYYGI KGEKSPHTRI IDILLDARRK YAYGDQIEYF DHPSTIGFIR TGDEEHNGSG
     LVFLMSNDEA GSKIMSLGEK HKGEVWHEIT GSISEEITLD EEGNGEFSVE SRNLAVWVKK
     D
//
DBGET integrated database retrieval system