ID A0A0U3PVC8_9ACTN Unreviewed; 4643 AA.
AC A0A0U3PVC8;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=OTU domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=AS200_04285 {ECO:0000313|EMBL:ALV31356.1};
OS Streptomyces sp. CdTB01.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1725411 {ECO:0000313|EMBL:ALV31356.1, ECO:0000313|Proteomes:UP000068029};
RN [1] {ECO:0000313|EMBL:ALV31356.1, ECO:0000313|Proteomes:UP000068029}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CdTB01 {ECO:0000313|EMBL:ALV31356.1,
RC ECO:0000313|Proteomes:UP000068029};
RA Tian Y., Zhou G., Yang H., Lu X.;
RT "Complete genome sequence of the Streptomyces sp. strain CdTB01, a
RT bacterium tolerant to cadmium.";
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
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DR EMBL; CP013743; ALV31356.1; -; Genomic_DNA.
DR RefSeq; WP_058921042.1; NZ_CP013743.1.
DR STRING; 1725411.AS200_04285; -.
DR KEGG; scx:AS200_04285; -.
DR OrthoDB; 1215854at2; -.
DR Proteomes; UP000068029; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR PANTHER; PTHR47246; MUCIN-19; 1.
DR PANTHER; PTHR47246:SF1; MUCIN-19; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000068029};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 148..172
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 184..208
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 220..238
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 286..350
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 365..576
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 701..729
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 747..804
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1134..1154
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1355..1405
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1658..1779
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1870..1904
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1932..1958
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1998..2023
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2103..2152
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2212..2281
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2400..2425
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2897..2919
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3014..3040
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3266..3301
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3341..3424
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3525..3547
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3559..3593
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 306..346
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 391..408
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 450..526
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1359..1373
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1741..1775
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1870..1897
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1942..1958
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3346..3360
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3385..3418
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 4643 AA; 497341 MW; 3BBC84D20ABF5B71 CRC64;
MSVEMPPELA WVARLAVGQA WPKGNEDDLH ALGQAWQDAA LELKGISGQI GASGNGVLES
VGGQVADEFR GFVTQLEASL PEMAESAGQL GKLGKHTAVQ VEYAKYMILG QLILLAAQIA
EWAFFAPEVI PVAITSARLA VKMILRRLLI SVATGVALNV GLDVAVQTIQ FLEGDRTQWS
TENTVSAVVS GAIGGAMGGL FFGAGGVLAP RFAHSLLGKG ILGAATGIST AGIMYGIYHS
GQDEFGTSIS AGALGALGGG GKRRFGGKGD TFKVDPVHVN VPDALTFGRS DLPAPVPAEK
PESPSATGTF KESTQNTGTT EKNTTGEATA PAVAATHGTS TSVSEPVAAP RDPAQVRELP
GFSTTVTTAH AAPSRGDAGT TAPMGRAATA QPRGTTGSGG TTGAAASATG ARPSAAATGA
RRSTEISTGT RAATPGPAPA VRTETGVSTR DEPRTSAPTE NAAETAPRPS AATRTQTGPD
PVRTTQATTA GAVTETAPPA GTTGEQHTAA PPPQVSAATT PTARTADASA PPDGDGTAPP
HRQTAATAPS PAPEPPTPLG GHRAAGREPA PRMTLDRTPR FVVRSGYEAR RFVYQDERFT
DLTIRVAFRD SGARHDVDAV WHRMADGVEE FLNAPRYRLP NGDRLHVTVV RARPGEEPHL
TVDLVGRDRA MDQRSWWPDA DPVDFAHEIG HQVGLRDEYR DRDTPHRPAV EGSLQGDYRA
PAPEGLRQAG LRDRHLRLIG AGIGDLGEPA VAGRAADEAP SPDRPASDGA PPYDAQWERA
RAAAQGHERS HTWVDPVSDP QGAARGVQRS MPAVAPRMHQ LLRPSVYSPD NMLVMQPGYA
SGDQFGILAM LLAEPNMHVL IARGPGPGEP GHDPILDKSR AIEAFYRESG IDEDRIWVLD
LPKLEQGNVW PQLNDAATDI AQYRWGINKD FHEMYEKGEL WGVSSGTDYV ARLFSPAMRS
ALRDAWHLEG HDPEIVAWLG EKGVRIPEGD KGVLVLWSRF TGKATQWSHL RGRMEHDTSF
EGTRQLIRNL AADYKAVIIT GDPHPDGTKA GKWDELVQQM RAELGTEHIH NLTGFWRSPT
PRLEAWGGDT RTGQFRLYDH LARLHSVQHL GFRSGNLEAV ALIGHPVRYL EESDSTGSSR
MSAWHAENKR PDSRRTLEPG YERIVVSAPP TASGRYAKQF EPKELQALYQ PPDPNSWFRK
PAEAYREEHG FGYEDVEQIR EDLRLTGAHQ EREAFDAARV RDVLRRYHKA VAEIRQYPDY
PRHAQTDVDR FLAPLDAIAA MHPATYAGGA TQMYADLVSG FLPRMPDVSS ILRRVRYSVA
WAHYAQQQAA VQASHQGVAP GGDEVMPRAP VADDLVTSSD GTAMVSRPTR SRPSDDVPSA
PAAESSAQAA ARAERSADHP AFSAVPTTDG FAELRHLSDT AVTETDASSR YGMPVANFRK
FRQFAADRGL RIDVRPTNPT SVRWLEEGKL PKPKEIKAKS INDLDVALGA RPEHRGLVGY
FEPVLPERGD HDEAVWSRIQ ARYAQRAEEF RVLAPVMADL RERGLFKVED GLVYGRDDRN
NWTEITGDHD LFDISTPGGT RLKGERQDEV VGAMKANAMA VMHPPHMSWE PTSPFSKSIY
NKIVESHQEG GEPLLRFRPD LLNAELVHAP REFLIKLPEP EPEPVPEQPE AKTVQPEPSA
APGLPLLTPP RIEYPVLHSP EPEGTIGARP VEPEVQPVAE SQPVTGNAVR DAEPEPMVVE
PDGEPATPDP PGDAPQPTEE PGDHAAPPPE PSGPPAQLRG RHLRSLAGIR ITDAPGPEEL
RARLVGMLPA AHAGDRQVVQ KLDVEFDPVA FRAGHEEMVN GGRRFQLRVN GVLHDVVLTA
RPAEWRLREE QAPDAEKTGK GFERSAEAKR ETEPKKTSLT TSEAGLDLAP TVIRSDGGHP
DRLAVINPSV KAGGATHATD TSVKEAAETG SKTSLTGPTD TYVSRFRYDV AVIGPDGRRR
SGPAGEPLVG EVTAEVTRPG AGRPEGEPAR WNGWESGRPG RPEGRPLDVT GLSGLHADVF
RHLPSEQRPD GTAHRDILEF LSPKNVVDGF EHAAGSGLVS KRLDLSDGGH AWLRLTLEPG
TSVHEGTVSG KDAFTSKETG EHGAGRTDTS GWGLGLNGGG ARRVRQSTTT EESTWLTVTG
GYTYARSEAH QEKGKQTFSV EHTLERAGTA DLIRTQVRFR VEVLREHLSP RADGLHDVRP
VPDPGSAPGG APRDVENPSA PRTGEVIRVR PHPATPPVAE AQDGTPSAAG PGTRPAPGDL
RAPLTAQRTA FVDVPGSTEL ERHITDRLRE VAPGVLPPPD IASGRVTPQA LESQRLLRAR
LSPSGLRADG GRLLDGTFRI TLDASHLPGL PGRAYEVVVR ADIGTGRHEG AAATTVKSTV
ARGHASEKGV TRGGKHTLGV SGNVRSALNP QDSVRAFGLA GVDGSYAPSR QTVAVGETQT
KRTFQHKGPV DAFSYPVGYR VLVASHREGD PPSALPARSV ADGGASGTVR DVVLAEGDRL
HVEVRRPEVS ASAPPYLRPG RLPQLHSVTH VGDEAGFRRQ AVTALRNAYD SRRADSEPPR
VPELDEAVDA LTGRAQLPGL VSASQAGWVN TLDRHVGDGR DPDTVGLSVR TRLTDLTYEE
TLSGDGTLDL ELKASAATTL GDQTSWSLKG NLGPDFGRFP ETATGALTTS YQLRGGVKAK
LGGQWDDTDT VKQQTTASRT AGHTGTWHVY RATAEVSVVG RITDATGAPH LGRALRRDHE
ILVLLSEEDA ALLRAADAAV ATARPPELRA TLLDQNISGG VLVDLPDTDA VLREIHEQVR
GPGDVAVPVA ALPFADTFAP DALAARYDEL VGPGILDRHV EVTRAGRVVT EVLVRGIPGT
WTDQGVRSDR PLTREVSAAD TVKGKSASKR SAGLEGSLRA AVRPPVAHLN SASLTPGAAF
EGSRGDGAES GVTTTIGHKT SGFGGESALF ATTLGYEVTV TRRTETGRFV HLPKTPATVG
PARATAWVPA SLTQSATAPP HPQVPNDPGR PAARPAPSAN HPFDIELART NAQARAERAA
WQNELDAAHD LVGFDRGKAL HDAAVETQAT PLPWGDGLLG QIGASYSWAL ARGTGLARWA
VRSALPEHLT ATVTRFLDTF AADPRLGRAH DLSREQRLTV EEQFAIRQAL SGQSPAALFH
RLTGRERVIR IPGTSLALSM EAIGPAEEVA RRDAADDELT VTVKDEADTS AADTANWNVS
PLDFSVLTED PVLNIPLNTG RMTRDQSYDV ARPVTRAPGT PGRPTPDSAL PHGRTATEPG
KVKITELAFL MRQPVRITIR RHDDATGNGA PRFVTGHVFH WSTTPAAGPP SASASRPGPS
QGRPTAPAAE PTAAPRPLRG PAPAPRSSGS QTDETAPRAP LTGATGATSA SGTADGGHPA
TATLTHGVTF GAEDATRPGP EEIAAIDALA AELAHDAVRR TTLGRTPPQI LISGHGTAAV
AGRPHFGRAF QLGAERADGV RDVLARRLDA HLRDLGSPLT SDAFTITTES RGPDLPHGTD
PAHDTPEARR RATITVVHRP DPDAVPTTPA AQRAHAVAQP PAADPRPPVR PEQWRARRDH
AVWAVLRTER YDPARDPAAD RPASGLLAGR DVVVRAAVAR IQADDGRWVR NLSLHLPVRF
GEGFTAADLG AYRERLQALL DTYVNDGRRL PGSGDQLHID VELEHRPDHA EAVEISRSER
PAAAWDQFTF PLGTHEGIRD DARALHEMLH YAGLPDRYHD TTTLFRRLER QSERTGLMAD
IDTIDVPDTY LRAIAEVTDS GPVLRDLPFT DGAKPPVTAP GPTGAEARET LLAADPEPHP
AGPVRPPAAA PFAGRSQAYV DDLMREVRHP QTETDHGRNW AGSGRPPLDT TNYVVVDVDG
RRTPYEVPWS DAYIVMARVR GDQITLETPG ATTPDGKIRL TDAEDFAALL ASDPRLPAGA
DIVLALLGRQ SAVSGLPQAV SEATGRRVWA PSAGTLRIAS QRIGSRKRER FELLDTDLRW
AATTSAAHPD HFAHLRAEHL LTQEYTVTAG DGDAVLFHRL PATRYESFSD ASRSDPDLPA
LTLPTQSLDV VPVGAFPDIR VSQDRTLAID GDGLSQHAYA TERAVDEANA RLAAAGSKVR
LTADPEVSLT FQREDGLPTP PLLRITPEFL TRSQRSEEEA CRDFAQMVSG QVRASHVVFR
VPGERVATAQ ISALDTAEVT GTHHLAESLA QVADGALDPA RTGPAWAAAQ TARDDRGVGG
QGGSPLPGRE YGSALGYGQV DDPRRYALTQ AARRTGINEA AWAEVGEGYL VQSINAADDD
GRPTLAFNHA KPTASNASHF GYHFATVVLA SEDGQTQITL ENHARVSRNR ATMSRAVELN
LESPAAGLRA LATVLEDRAR FAERVNADEG HQNALRARAR LADRLAAARE ARDRGAPVEE
QERTFQQAAT AMLRAAPMID GKHQWYFRSY SRRPGESMHE SHAELLSRDY SAEANPLTLV
VLHGHGVSAP EHRFIPFEAS GAMADSAGFK LGHLAEQLVR SGLWNLAHGL PLPAVRLTGH
DGGSAPQPDL EFTAAMAETV RDALRLRLAD VLREHGSDTD PDAFRVTVAS GLRRHDGRGQ
APEVTFEVDD WRDSRDDHEG ARG
//
