ID A0A0U3T6F5_9ACTN Unreviewed; 489 AA.
AC A0A0U3T6F5;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Cell division protein FtsI {ECO:0000313|EMBL:ALX06184.1};
GN ORFNames=AERYTH_16515 {ECO:0000313|EMBL:ALX06184.1};
OS Aeromicrobium erythreum.
OC Bacteria; Actinomycetota; Actinomycetes; Propionibacteriales;
OC Nocardioidaceae; Aeromicrobium.
OX NCBI_TaxID=2041 {ECO:0000313|EMBL:ALX06184.1, ECO:0000313|Proteomes:UP000067689};
RN [1] {ECO:0000313|EMBL:ALX06184.1, ECO:0000313|Proteomes:UP000067689}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AR18 {ECO:0000313|EMBL:ALX06184.1,
RC ECO:0000313|Proteomes:UP000067689};
RX PubMed=1883712;
RA Miller E.S., Woese C.R., Brenner S.;
RT "Description of the erythromycin-producing bacterium Arthrobacter sp.
RT strain NRRL B-3381 as Aeromicrobium erythreum gen. nov., sp. nov.";
RL Int. J. Syst. Bacteriol. 41:363-368(1991).
CC -!- SIMILARITY: Belongs to the transpeptidase family.
CC {ECO:0000256|ARBA:ARBA00007171}.
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DR EMBL; CP011502; ALX06184.1; -; Genomic_DNA.
DR RefSeq; WP_067860878.1; NZ_CP011502.1.
DR AlphaFoldDB; A0A0U3T6F5; -.
DR STRING; 2041.AERYTH_16515; -.
DR KEGG; aer:AERYTH_16515; -.
DR PATRIC; fig|2041.4.peg.3455; -.
DR OrthoDB; 9766847at2; -.
DR Proteomes; UP000067689; Chromosome.
DR GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR036138; PBP_dimer_sf.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR PANTHER; PTHR30627:SF24; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE PBPA; 1.
DR Pfam; PF00905; Transpeptidase; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000313|EMBL:ALX06184.1};
KW Cell division {ECO:0000313|EMBL:ALX06184.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000067689}.
FT DOMAIN 159..484
FT /note="Penicillin-binding protein transpeptidase"
FT /evidence="ECO:0000259|Pfam:PF00905"
SQ SEQUENCE 489 AA; 51380 MW; B4A70A31EFBD53F2 CRC64;
MNKPIRNLAV ACLVLFAALL INVNYVQFVE AGDLNARQGN KRVIDADFSR DRGAILVGDE
PVAESKPSKD QYKFQRVYPQ STLYAPLTGY FSYIYGSANL ERSQNQVLSG SDNRLFVSRV
VDLLANKKPQ GGSVELTINP RAQKVAASGL EALGEGTKGA VAALDPKTGA VLAMVSQPSY
DPNVLASHDF SKVTEAMKRL QANEDDPLTN RATQQILPPG STFKLVTAAA ALEDLNLKAD
SRVKGGASLS FPGIQYTLPN ENGGNCGGDP ITFEQALQVS CNVSFGDLAG KIGQDKLDEQ
ARKFGFGTDP LEGLASNASQ FTAEGTDLEA PQLAQSGIGQ FEVAATPLQM AMVGAGIAND
GVVMKPQVVK SVRSPSLRVL DSLEPEELDR AMSADNAAIL RSMMVATVQS GTATSAQIPG
VQVGAKTGTA QSTPDRPPYA WFVALAPAND PKVAVAVVVE SSSTARNEIA GGRLAGPIAR
SVIEAVLGE
//
