ID A0A1A9J3K9_9ACTN Unreviewed; 354 AA.
AC A0A1A9J3K9;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=DNA ligase (ATP) {ECO:0000256|ARBA:ARBA00012727};
DE EC=6.5.1.1 {ECO:0000256|ARBA:ARBA00012727};
GN ORFNames=A8713_27125 {ECO:0000313|EMBL:ANH94402.1};
OS Streptomyces sp. SAT1.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1849967 {ECO:0000313|EMBL:ANH94402.1, ECO:0000313|Proteomes:UP000078022};
RN [1] {ECO:0000313|EMBL:ANH94402.1, ECO:0000313|Proteomes:UP000078022}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SAT1 {ECO:0000313|EMBL:ANH94402.1,
RC ECO:0000313|Proteomes:UP000078022};
RA Dou G.;
RT "Complete genome of endophytic Streptomyces sp.";
RL Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + (deoxyribonucleotide)n-3'-hydroxyl + 5'-phospho-
CC (deoxyribonucleotide)m = (deoxyribonucleotide)n+m + AMP +
CC diphosphate.; EC=6.5.1.1; Evidence={ECO:0000256|ARBA:ARBA00034003};
CC -!- SIMILARITY: Belongs to the ATP-dependent DNA ligase family.
CC {ECO:0000256|ARBA:ARBA00007572}.
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DR EMBL; CP015849; ANH94402.1; -; Genomic_DNA.
DR RefSeq; WP_064536291.1; NZ_CP015849.1.
DR AlphaFoldDB; A0A1A9J3K9; -.
DR STRING; 1849967.A8713_27125; -.
DR KEGG; strt:A8713_27125; -.
DR Proteomes; UP000078022; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0003910; F:DNA ligase (ATP) activity; IEA:UniProtKB-EC.
DR GO; GO:0006310; P:DNA recombination; IEA:InterPro.
DR GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR CDD; cd07905; Adenylation_DNA_ligase_LigC; 1.
DR CDD; cd07970; OBF_DNA_ligase_LigC; 1.
DR Gene3D; 3.30.470.30; DNA ligase/mRNA capping enzyme; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR InterPro; IPR044119; Adenylation_LigC-like.
DR InterPro; IPR012309; DNA_ligase_ATP-dep_C.
DR InterPro; IPR012310; DNA_ligase_ATP-dep_cent.
DR InterPro; IPR016059; DNA_ligase_ATP-dep_CS.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR044117; OBF_LigC-like.
DR PANTHER; PTHR45674; DNA LIGASE 1/3 FAMILY MEMBER; 1.
DR PANTHER; PTHR45674:SF9; DNA LIGASE 3; 1.
DR Pfam; PF04679; DNA_ligase_A_C; 1.
DR Pfam; PF01068; DNA_ligase_A_M; 1.
DR SUPFAM; SSF56091; DNA ligase/mRNA capping enzyme, catalytic domain; 1.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
DR PROSITE; PS00697; DNA_LIGASE_A1; 1.
PE 3: Inferred from homology;
KW Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000313|EMBL:ANH94402.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000078022}.
FT DOMAIN 11..197
FT /note="ATP-dependent DNA ligase family profile"
FT /evidence="ECO:0000259|Pfam:PF01068"
FT DOMAIN 216..330
FT /note="DNA ligase ATP-dependent C-terminal"
FT /evidence="ECO:0000259|Pfam:PF04679"
SQ SEQUENCE 354 AA; 39444 MW; 5756F68693557A9C CRC64;
MELPVMPPVK PMLAKPVARI PPGMHYEAKW DGFRAIVFRD GAEVELGSRT GKPLTRYFPE
LVAAFRERLP ERCVLDGEIV IAREGRLDFD ALTERIHPAD SRVRALAERT PASFVAFDLL
ALDAETLLDV ALADRRALLE RALAGAGAPV HVAPATTDID VARQWFEQYE GAGLDGVIAK
PPGLPYLQDQ RAMFKIKHER TADVVVAGYR LHKSGPVVGS LLLGLYDGRG VLQHVGVAAA
FPMKRRAELI EELAPLRMDD PAGHPWAAWS EEAAHESARL PGAPSRWSGR KDLSWVPLRP
ERVAEVAYDH MENGARFRHT ARFRRWRPDR APESCTYAQL EEPVRYDLAR ILGP
//
