ID A0A1B0VHF6_FERIS Unreviewed; 560 AA.
AC A0A1B0VHF6;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE SubName: Full=2-oxoacid:acceptor oxidoreductase subunit alpha {ECO:0000313|EMBL:AMW32165.1};
GN ORFNames=NA23_01795 {ECO:0000313|EMBL:AMW32165.1};
OS Fervidobacterium islandicum.
OC Bacteria; Thermotogota; Thermotogae; Thermotogales; Fervidobacteriaceae;
OC Fervidobacterium.
OX NCBI_TaxID=2423 {ECO:0000313|EMBL:AMW32165.1, ECO:0000313|Proteomes:UP000093740};
RN [1] {ECO:0000313|EMBL:AMW32165.1, ECO:0000313|Proteomes:UP000093740}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AW-1 {ECO:0000313|EMBL:AMW32165.1,
RC ECO:0000313|Proteomes:UP000093740};
RX PubMed=26421103; DOI=10.1186/s40793-015-0063-4;
RA Lee Y.J., Jeong H., Park G.S., Kwak Y., Lee S.J., Lee S.J., Park M.K.,
RA Kim J.Y., Kang H.K., Shin J.H., Lee D.W.;
RT "Genome sequence of a native-feather degrading extremely thermophilic
RT Eubacterium, Fervidobacterium islandicum AW-1.";
RL Stand. Genomic Sci. 10:71-71(2015).
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DR EMBL; CP014334; AMW32165.1; -; Genomic_DNA.
DR RefSeq; WP_033191330.1; NZ_CP014334.2.
DR AlphaFoldDB; A0A1B0VHF6; -.
DR STRING; 2423.NA23_01795; -.
DR KEGG; fia:NA23_01795; -.
DR eggNOG; COG0674; Bacteria.
DR eggNOG; COG1014; Bacteria.
DR OrthoDB; 9794954at2; -.
DR Proteomes; UP000093740; Chromosome.
DR GO; GO:0016903; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors; IEA:InterPro.
DR CDD; cd07034; TPP_PYR_PFOR_IOR-alpha_like; 1.
DR Gene3D; 3.40.50.920; -; 1.
DR Gene3D; 3.40.50.970; -; 1.
DR Gene3D; 3.40.920.10; Pyruvate-ferredoxin oxidoreductase, PFOR, domain III; 1.
DR InterPro; IPR022367; 2-oxoacid/accept_OxRdtase_asu.
DR InterPro; IPR019752; Pyrv/ketoisovalerate_OxRed_cat.
DR InterPro; IPR002880; Pyrv_Fd/Flavodoxin_OxRdtase_N.
DR InterPro; IPR002869; Pyrv_flavodox_OxRed_cen.
DR InterPro; IPR029061; THDP-binding.
DR InterPro; IPR009014; Transketo_C/PFOR_II.
DR NCBIfam; TIGR03710; OAFO_sf; 1.
DR PANTHER; PTHR32154:SF20; 2-OXOGLUTARATE OXIDOREDUCTASE SUBUNIT KORA; 1.
DR PANTHER; PTHR32154; PYRUVATE-FLAVODOXIN OXIDOREDUCTASE-RELATED; 1.
DR Pfam; PF01558; POR; 1.
DR Pfam; PF01855; POR_N; 1.
DR SUPFAM; SSF53323; Pyruvate-ferredoxin oxidoreductase, PFOR, domain III; 1.
DR SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 1.
DR SUPFAM; SSF52922; TK C-terminal domain-like; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT DOMAIN 15..172
FT /note="Pyruvate/ketoisovalerate oxidoreductase catalytic"
FT /evidence="ECO:0000259|Pfam:PF01558"
FT DOMAIN 203..436
FT /note="Pyruvate flavodoxin/ferredoxin oxidoreductase
FT pyrimidine binding"
FT /evidence="ECO:0000259|Pfam:PF01855"
SQ SEQUENCE 560 AA; 62175 MW; 8ADDBEBC606D918B CRC64;
MEKKSEISIV LSGAAGQGIQ AVEHILTRVA KDSGFHVFAT KEYMSRVRGG NNSTEIRISS
QPVKAYVDRI DILVPLNDNA IERLRSRITD ETLILGEKRY VEKEKNSIGL MLEEIAESFG
NKIYENSVAI GVLAGIINAD ENALVNNIRA YFLKKSEEVV KANINAALKG YEIGKSFGLK
FEITPSEEVK KQYLLNGSEA VAKGAIAGGC NFISSYPMSP ATTVFTELSR LSRQHGILVD
QAEDEIAAAN MAIAAWYAGA RAMVSTSGGG FALMTEAISL SGMIETPIVV HLGQRPGPAT
GLPTRTEQGD LNLVLYAGHG DFPRIIYAPG NLCEAYELGA RAFNMADKYQ VPVFVLTDQY
FLDSFYNVDE MPQAKIERYI IKTDENYKRY ALTDDGISPR GIPGYGKGLV RVDSDEHDEY
GHITESAEVR RKMVEKRLKK MEKILQDAVP PKLFGSEDYK YLIVTWGSTQ LIVREALERL
GKKDVAMLHF SQVYPVPPIA ENYFKKAEKI IFLEQNAIGQ FANLIKLTFD GVDTRRRILK
YDGFPFSVEQ VVEAISKEVE
//
