ID A0A1B2HNZ8_9PSEU Unreviewed; 557 AA.
AC A0A1B2HNZ8;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=AMP-dependent synthetase {ECO:0000313|EMBL:ANZ39436.1};
GN ORFNames=BBK82_28690 {ECO:0000313|EMBL:ANZ39436.1};
OS Lentzea guizhouensis.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Lentzea.
OX NCBI_TaxID=1586287 {ECO:0000313|EMBL:ANZ39436.1, ECO:0000313|Proteomes:UP000093053};
RN [1] {ECO:0000313|EMBL:ANZ39436.1, ECO:0000313|Proteomes:UP000093053}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DHS C013 {ECO:0000313|EMBL:ANZ39436.1,
RC ECO:0000313|Proteomes:UP000093053};
RA Cao C.;
RT "Complete genome sequence of the Lentzea guizhouensis DHS C013.";
RL Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the ATP-dependent AMP-binding enzyme family.
CC {ECO:0000256|ARBA:ARBA00006432}.
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DR EMBL; CP016793; ANZ39436.1; -; Genomic_DNA.
DR RefSeq; WP_065917777.1; NZ_CP016793.1.
DR AlphaFoldDB; A0A1B2HNZ8; -.
DR STRING; 1586287.BBK82_28690; -.
DR KEGG; led:BBK82_28690; -.
DR OrthoDB; 9803968at2; -.
DR Proteomes; UP000093053; Chromosome.
DR GO; GO:0016878; F:acid-thiol ligase activity; IEA:UniProt.
DR GO; GO:0016405; F:CoA-ligase activity; IEA:UniProt.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR PANTHER; PTHR43605:SF10; ACYL-COA SYNTHETASE MEDIUM CHAIN FAMILY MEMBER 3; 1.
DR PANTHER; PTHR43605; ACYL-COENZYME A SYNTHETASE; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 3: Inferred from homology;
KW Ligase {ECO:0000256|ARBA:ARBA00022598};
KW Reference proteome {ECO:0000313|Proteomes:UP000093053}.
FT DOMAIN 47..399
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 450..527
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 557 AA; 61298 MW; 9BBE3B830085425F CRC64;
MASHDTYRAA RDLMLTDPES FRWPSFPDAF NWAHDWFDVI AEGNAATALH IVEEDGRERA
YSFDELRRRS NRVAHWLAGH GVGKGDSVMI MLGNQVELWE SMLAVMKLGA VIMPTTTALG
PADLGDRLRR GTVRHVVARA EDAGNVEGVP EAGTGTVLIA VGGTPAGWVG YTDADSSPDE
PLPHPQTRAE DRLLLYFTSG TTSRPKLVEH TQVSYPAGHV TTMRWIGVKP GDVHLNISSP
GWAKHAWSCF FAPWIAEATI FVYNYTRFDA AALLGQIRAK RVTTFCAPPT VWRMLIKADL
SGGPGELREV VAAGEPLNPE VVEQVGQHWG LTLRDGFGQT ETTLSVGNLP GDQVKLGSMG
RPLPGVPVVL VDPITGERAD EGEICIDLGE RPMSLMVGYF GDDERNAEAM AGGYYHTGDI
ASRDEDGYLF YIGRSDDVFK ASDYKISPFE LESVLIEHPA VTEAAVVPAP DPVRLAVPKA
YVALSPGWEP TRETALEILR HARENLAPYQ RIRRLEFAVL PKTVSGKIRR VDLRGREEQG
VDQAGEWRDE QFPELRK
//
