ID A0A1E7ET48_9STRA Unreviewed; 732 AA.
AC A0A1E7ET48;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=Ribokinase {ECO:0000256|ARBA:ARBA00016943};
GN Name=RBSK1_1 {ECO:0000313|EMBL:OEU08974.1};
GN ORFNames=FRACYDRAFT_196000 {ECO:0000313|EMBL:OEU08974.1};
OS Fragilariopsis cylindrus CCMP1102.
OC Eukaryota; Sar; Stramenopiles; Ochrophyta; Bacillariophyta;
OC Bacillariophyceae; Bacillariophycidae; Bacillariales; Bacillariaceae;
OC Fragilariopsis.
OX NCBI_TaxID=635003 {ECO:0000313|EMBL:OEU08974.1, ECO:0000313|Proteomes:UP000095751};
RN [1] {ECO:0000313|EMBL:OEU08974.1, ECO:0000313|Proteomes:UP000095751}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCMP1102 {ECO:0000313|EMBL:OEU08974.1,
RC ECO:0000313|Proteomes:UP000095751};
RG DOE Joint Genome Institute;
RA Mock T., Otillar R.P., Strauss J., Dupont C., Frickenhaus S., Maumus F.,
RA Mcmullan M., Sanges R., Schmutz J., Toseland A., Valas R., Veluchamy A.,
RA Ward B.J., Allen A., Barry K., Falciatore A., Ferrante M., Fortunato A.E.,
RA Gloeckner G., Gruber A., Hipkin R., Janech M., Kroth P., Leese F.,
RA Lindquist E., Lyon B.R., Martin J., Mayer C., Parker M., Quesneville H.,
RA Raymond J., Uhlig C., Valentin K.U., Worden A.Z., Armbrust E.V., Bowler C.,
RA Green B., Moulton V., Van Oosterhout C., Grigoriev I.;
RT "Extensive genetic diversity and differential bi-allelic expression allows
RT diatom success in the polar Southern Ocean.";
RL Submitted (SEP-2016) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KV784378; OEU08974.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1E7ET48; -.
DR EnsemblProtists; OEU08974; OEU08974; FRACYDRAFT_196000.
DR KEGG; fcy:FRACYDRAFT_196000; -.
DR InParanoid; A0A1E7ET48; -.
DR OrthoDB; 324851at2759; -.
DR Proteomes; UP000095751; Unassembled WGS sequence.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016773; F:phosphotransferase activity, alcohol group as acceptor; IEA:UniProt.
DR GO; GO:0071704; P:organic substance metabolic process; IEA:UniProt.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR GO; GO:0044238; P:primary metabolic process; IEA:UniProt.
DR Gene3D; 3.40.1190.20; -; 1.
DR Gene3D; 3.20.20.150; Divalent-metal-dependent TIM barrel enzymes; 1.
DR InterPro; IPR011611; PfkB_dom.
DR InterPro; IPR002139; Ribo/fructo_kinase.
DR InterPro; IPR029056; Ribokinase-like.
DR InterPro; IPR036237; Xyl_isomerase-like_sf.
DR InterPro; IPR013022; Xyl_isomerase-like_TIM-brl.
DR PANTHER; PTHR10584:SF166; RIBOKINASE; 1.
DR PANTHER; PTHR10584; SUGAR KINASE; 1.
DR Pfam; PF01261; AP_endonuc_2; 1.
DR Pfam; PF00294; PfkB; 1.
DR PRINTS; PR00990; RIBOKINASE.
DR SUPFAM; SSF53613; Ribokinase-like; 1.
DR SUPFAM; SSF51658; Xylose isomerase-like; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:OEU08974.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000095751};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transferase {ECO:0000313|EMBL:OEU08974.1}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 22..732
FT /note="Ribokinase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5009192213"
FT DOMAIN 41..367
FT /note="Carbohydrate kinase PfkB"
FT /evidence="ECO:0000259|Pfam:PF00294"
FT DOMAIN 464..687
FT /note="Xylose isomerase-like TIM barrel"
FT /evidence="ECO:0000259|Pfam:PF01261"
FT REGION 357..383
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 368..383
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 732 AA; 80305 MW; 57F7C33084826EB8 CRC64;
MPKLLPISAL HFWAFAFLAA AATTTTVVQV VVAATVPSSP SVLVVGSANA DTFLPVERLP
TEGENLTLIP NSEPIVDVAG GKGVTQAVAV SKILSSTSTS TSTSTPKTLF IGQLGLDHAG
KMLHQTLDMA GVICSQCGFH SDISSGRGYV FLQKQTGSVS AVVSGGTNMM GWKGWEKAWE
EKQKIRQSAT TAKTLDEEHI RCVLLQREVP EYVNLLIASC VEDYNNQCDD DNNKIVVFQD
VGGEDRPISK EMLELCDYIV PNESELKRLV ESSSPSTSST LFTNVLVTRG SSGSMLLAKD
GTVTFQSAIR CDNDAVVDET GAGDCFRAAF AVAYIIEGWD LKRSLLFASA AGSCSVEKNG
AVPSTPDRDE VSASSTSTSS RHPTFVSRVS DNMLRGGGED AFPFLIGSRL NSMKDRPDLW
RGNSSSSPPL ETPRDYVQRQ ATIRGLTCVD FNFPQHFGSF WTPPEAKKAL NEVGLVAGAV
CLRYPAKFAR GAMNHPDYEL RREAIELTKE AAEAANELGC DEVVIWSAFD GYDYPFQVDY
DEKWDQLVSA FQELCDSYPN IKFSLEYKPT DENTRFFTVP TTGAALLLVE EIDRSNMGLT
LDVGHMLMAG ENPGQSIAMV GRKRKLFGIQ LNDGFTRLAA EDGLMFGSVH PSMALEIMYQ
LHKTEFKGHL YFDTFPQRSD PVKEAEYNIR QVKRFWNAAK YDIDDSLLRQ ITNEHDAIGA
LELVDKALRY VR
//
