ID A0A1W7ABL4_9STAP Unreviewed; 66 AA.
AC A0A1W7ABL4;
DT 05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2017, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE RecName: Full=Exodeoxyribonuclease 7 small subunit {ECO:0000256|HAMAP-Rule:MF_00337};
DE EC=3.1.11.6 {ECO:0000256|HAMAP-Rule:MF_00337};
DE AltName: Full=Exodeoxyribonuclease VII small subunit {ECO:0000256|HAMAP-Rule:MF_00337};
DE Short=Exonuclease VII small subunit {ECO:0000256|HAMAP-Rule:MF_00337};
GN Name=xseB {ECO:0000256|HAMAP-Rule:MF_00337,
GN ECO:0000313|EMBL:ARQ07003.1};
GN ORFNames=ETI04_02410 {ECO:0000313|EMBL:TDM18365.1}, GL258_07305
GN {ECO:0000313|EMBL:QNR08075.1}, KFV07_07210
GN {ECO:0000313|EMBL:UTH05978.1}, MCCS_13610
GN {ECO:0000313|EMBL:ARQ07003.1};
OS Macrococcus canis.
OC Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae; Macrococcus.
OX NCBI_TaxID=1855823 {ECO:0000313|EMBL:ARQ07003.1, ECO:0000313|Proteomes:UP000194154};
RN [1] {ECO:0000313|EMBL:ARQ07003.1, ECO:0000313|Proteomes:UP000194154}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KM45013 {ECO:0000313|EMBL:ARQ07003.1,
RC ECO:0000313|Proteomes:UP000194154};
RX PubMed=27902286; DOI=10.1099/ijsem.0.001673;
RA Gobeli Brawand S., Cotting K., Gomez-Sanz E., Collaud A., Thomann A.,
RA Brodard I., Rodriguez-Campos S., Strauss C., Perreten V.;
RT "Macrococcus canis sp. nov., a skin bacterium associated with infections in
RT dogs.";
RL Int. J. Syst. Evol. Microbiol. 67:621-626(2017).
RN [2] {ECO:0000313|EMBL:ARQ07003.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=KM45013 {ECO:0000313|EMBL:ARQ07003.1};
RA Afonso C.L., Miller P.J., Scott M.A., Spackman E., Goraichik I.,
RA Dimitrov K.M., Suarez D.L., Swayne D.E.;
RL Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:TDM18365.1, ECO:0000313|Proteomes:UP000294865}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DPC7162 {ECO:0000313|EMBL:TDM18365.1,
RC ECO:0000313|Proteomes:UP000294865};
RA Mazhar S., Altermann E., Hill C., Mcauliffe O.;
RT "Draft genome sequences of Macrococcus caseolyticus, Macrococcus canis,
RT Macrococcus bohemicus and Macrococcus goetzii.";
RL Submitted (JAN-2019) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|EMBL:QNR08075.1, ECO:0000313|Proteomes:UP000516310}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Epi0082 {ECO:0000313|EMBL:QNR08075.1,
RC ECO:0000313|Proteomes:UP000516310};
RA Fernandez J.E., Perreten V., Schwendener S.;
RT "The novel macrolide resistance genes mef(F) and msr(G) are located on a
RT plasmid in Macrococcus canis and a transposon in Macrococcus
RT caseolyticus.";
RL J. Antimicrob. Chemother. 76:48-54(2020).
RN [5] {ECO:0000313|EMBL:UTH05978.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Epi0100-OL {ECO:0000313|EMBL:UTH05978.1};
RA Schwendener S., Perreten V.;
RT "Complete Genome Sequences of Macrococcus spp. from dog and cattle.";
RL Submitted (APR-2021) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Bidirectionally degrades single-stranded DNA into large acid-
CC insoluble oligonucleotides, which are then degraded further into small
CC acid-soluble oligonucleotides. {ECO:0000256|HAMAP-Rule:MF_00337}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-
CC direction to yield nucleoside 5'-phosphates.; EC=3.1.11.6;
CC Evidence={ECO:0000256|HAMAP-Rule:MF_00337};
CC -!- SUBUNIT: Heterooligomer composed of large and small subunits.
CC {ECO:0000256|HAMAP-Rule:MF_00337}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00337}.
CC -!- SIMILARITY: Belongs to the XseB family. {ECO:0000256|ARBA:ARBA00009998,
CC ECO:0000256|HAMAP-Rule:MF_00337}.
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DR EMBL; CP021059; ARQ07003.1; -; Genomic_DNA.
DR EMBL; CP046363; QNR08075.1; -; Genomic_DNA.
DR EMBL; SDQG01000001; TDM18365.1; -; Genomic_DNA.
DR EMBL; CP073804; UTH05978.1; -; Genomic_DNA.
DR STRING; 1855823.MCCS_13610; -.
DR KEGG; mcak:MCCS_13610; -.
DR OrthoDB; 9798666at2; -.
DR Proteomes; UP000194154; Chromosome.
DR Proteomes; UP000294865; Unassembled WGS sequence.
DR Proteomes; UP000516310; Chromosome.
DR Proteomes; UP001056886; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0009318; C:exodeoxyribonuclease VII complex; IEA:InterPro.
DR GO; GO:0008855; F:exodeoxyribonuclease VII activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006308; P:DNA catabolic process; IEA:UniProtKB-UniRule.
DR Gene3D; 1.10.287.1040; Exonuclease VII, small subunit; 1.
DR HAMAP; MF_00337; Exonuc_7_S; 1.
DR InterPro; IPR003761; Exonuc_VII_S.
DR InterPro; IPR037004; Exonuc_VII_ssu_sf.
DR NCBIfam; TIGR01280; xseB; 1.
DR PANTHER; PTHR34137; EXODEOXYRIBONUCLEASE 7 SMALL SUBUNIT; 1.
DR PANTHER; PTHR34137:SF1; EXODEOXYRIBONUCLEASE 7 SMALL SUBUNIT; 1.
DR Pfam; PF02609; Exonuc_VII_S; 1.
DR PIRSF; PIRSF006488; Exonuc_VII_S; 1.
DR SUPFAM; SSF116842; XseB-like; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490, ECO:0000256|HAMAP-Rule:MF_00337};
KW Exonuclease {ECO:0000256|ARBA:ARBA00022839, ECO:0000256|HAMAP-
KW Rule:MF_00337};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|HAMAP-Rule:MF_00337};
KW Nuclease {ECO:0000256|ARBA:ARBA00022722, ECO:0000256|HAMAP-Rule:MF_00337}.
FT COILED 2..29
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 66 AA; 7539 MW; D4DCF5C97B0B8610 CRC64;
MAKTFEEMMQ QLESIVKALD DEQVSLEKSI ELYEQGVKLS QACQVKLTEA EEKITKLNST
EETTNE
//
