ID A1C7S0_ASPCL Unreviewed; 457 AA.
AC A1C7S0;
DT 23-JAN-2007, integrated into UniProtKB/TrEMBL.
DT 23-JAN-2007, sequence version 1.
DT 27-MAR-2024, entry version 99.
DE SubName: Full=TRAF-like signal transducer, putative {ECO:0000313|EMBL:EAW14441.1};
GN ORFNames=ACLA_074780 {ECO:0000313|EMBL:EAW14441.1};
OS Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 /
OS NRRL 1 / QM 1276 / 107).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Fumigati.
OX NCBI_TaxID=344612 {ECO:0000313|EMBL:EAW14441.1, ECO:0000313|Proteomes:UP000006701};
RN [1] {ECO:0000313|EMBL:EAW14441.1, ECO:0000313|Proteomes:UP000006701}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1
RC {ECO:0000313|Proteomes:UP000006701};
RX PubMed=18404212; DOI=10.1371/journal.pgen.1000046;
RA Fedorova N.D., Khaldi N., Joardar V.S., Maiti R., Amedeo P., Anderson M.J.,
RA Crabtree J., Silva J.C., Badger J.H., Albarraq A., Angiuoli S., Bussey H.,
RA Bowyer P., Cotty P.J., Dyer P.S., Egan A., Galens K., Fraser-Liggett C.M.,
RA Haas B.J., Inman J.M., Kent R., Lemieux S., Malavazi I., Orvis J.,
RA Roemer T., Ronning C.M., Sundaram J.P., Sutton G., Turner G., Venter J.C.,
RA White O.R., Whitty B.R., Youngman P., Wolfe K.H., Goldman G.H.,
RA Wortman J.R., Jiang B., Denning D.W., Nierman W.C.;
RT "Genomic islands in the pathogenic filamentous fungus Aspergillus
RT fumigatus.";
RL PLoS Genet. 4:E1000046-E1000046(2008).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; DS027045; EAW14441.1; -; Genomic_DNA.
DR RefSeq; XP_001275867.1; XM_001275866.1.
DR AlphaFoldDB; A1C7S0; -.
DR STRING; 344612.A1C7S0; -.
DR EnsemblFungi; EAW14441; EAW14441; ACLA_074780.
DR GeneID; 4707540; -.
DR KEGG; act:ACLA_074780; -.
DR VEuPathDB; FungiDB:ACLA_074780; -.
DR eggNOG; KOG0297; Eukaryota.
DR HOGENOM; CLU_019709_1_1_1; -.
DR OMA; PLTTICG; -.
DR OrthoDB; 3088759at2759; -.
DR Proteomes; UP000006701; Unassembled WGS sequence.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 3.
DR InterPro; IPR027370; Znf-RING_euk.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR017907; Znf_RING_CS.
DR InterPro; IPR001293; Znf_TRAF.
DR PANTHER; PTHR10131:SF157; RING-TYPE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR10131; TNF RECEPTOR ASSOCIATED FACTOR; 1.
DR Pfam; PF13445; zf-RING_UBOX; 1.
DR Pfam; PF02176; zf-TRAF; 1.
DR SMART; SM00184; RING; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR SUPFAM; SSF49599; TRAF domain-like; 2.
DR PROSITE; PS00518; ZF_RING_1; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
DR PROSITE; PS50145; ZF_TRAF; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723, ECO:0000256|PROSITE-
KW ProRule:PRU00207}; Reference proteome {ECO:0000313|Proteomes:UP000006701};
KW Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|PROSITE-ProRule:PRU00207};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00207}.
FT DOMAIN 36..80
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT DOMAIN 178..232
FT /note="TRAF-type"
FT /evidence="ECO:0000259|PROSITE:PS50145"
FT ZN_FING 178..232
FT /note="TRAF-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00207"
FT REGION 292..327
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 400..457
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 299..327
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 404..437
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 457 AA; 50866 MW; 9597EBDB0B760DCE CRC64;
MKLEELLMME SSCDRDELVD LRGLDYVTSF DDHLMCPICH CPFIRPVRLQ CDHVFCQKCL
NSAITSFAAG RDDFTCPTCR SPTRDVYLNV PRLLINMCDD VRVKCPFTAE GCKEIVPRGH
IQSHVDKYCG YSLMDCPSAV CDRKTRKKDL NPEQKCMHQL HQCSRCEEEV MEQDYEEHVK
ELCPSLRTTC PDCQTMVFRK ALREHIDTCS EAIHACAASK YGCPVKVKRA DLTNHQQICP
LIAMGPYFET QNARLDSMEL TIRHLQQRNE IFEDGIANIR STLLDASRAL PGQDMDLRSG
SSGHPTPSSS RYAADDQSHM DGSNASASNA ATTTYLLALH ESLREEVGQL SHAITDLDAR
ASMAIMNECL RLKEDMAHTN AAVSSIRMQV QWLMNPRLHQ GQRAAGVRSN TGGNGNNQEP
RPGQLGSSNS GPSSSAGPSG LLRPRRPSDS GREGTKL
//
