ID A3MSH5_PYRCJ Unreviewed; 649 AA.
AC A3MSH5;
DT 03-APR-2007, integrated into UniProtKB/TrEMBL.
DT 03-APR-2007, sequence version 1.
DT 27-MAR-2024, entry version 62.
DE SubName: Full=AMP-dependent synthetase and ligase {ECO:0000313|EMBL:ABO07592.1};
GN OrderedLocusNames=Pcal_0155 {ECO:0000313|EMBL:ABO07592.1};
OS Pyrobaculum calidifontis (strain DSM 21063 / JCM 11548 / VA1).
OC Archaea; Thermoproteota; Thermoprotei; Thermoproteales; Thermoproteaceae;
OC Pyrobaculum.
OX NCBI_TaxID=410359 {ECO:0000313|EMBL:ABO07592.1, ECO:0000313|Proteomes:UP000001431};
RN [1] {ECO:0000313|EMBL:ABO07592.1, ECO:0000313|Proteomes:UP000001431}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 21063 / JCM 11548 / VA1
RC {ECO:0000313|Proteomes:UP000001431};
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E.,
RA Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J.,
RA Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Cozen A.E.,
RA Fitz-Gibbon S.T., House C.H., Saltikov C., Lowe T.M., Richardson P.;
RT "Complete sequence of Pyrobaculum calidifontis JCM 11548.";
RL Submitted (FEB-2007) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP000561; ABO07592.1; -; Genomic_DNA.
DR AlphaFoldDB; A3MSH5; -.
DR STRING; 410359.Pcal_0155; -.
DR KEGG; pcl:Pcal_0155; -.
DR eggNOG; arCOG01529; Archaea.
DR HOGENOM; CLU_000022_3_6_2; -.
DR OrthoDB; 193284at2157; -.
DR Proteomes; UP000001431; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR032387; ACAS_N.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR PANTHER; PTHR24095; ACETYL-COENZYME A SYNTHETASE; 1.
DR PANTHER; PTHR24095:SF232; ACETYL-COENZYME A SYNTHETASE; 1.
DR Pfam; PF16177; ACAS_N; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000313|EMBL:ABO07592.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT DOMAIN 8..58
FT /note="Acetyl-coenzyme A synthetase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16177"
FT DOMAIN 67..461
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 525..603
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 649 AA; 73730 MW; 1C3DFFF58E6466C9 CRC64;
MRSFFPNYEL SLKDPETYWR RVLEASAEDI YWAKWPDKIF EWEPPKPFKW FVGGYTNAGF
SAVSYKIRKY RDKPAYIYYS PELGVERKIT YWELYQLVCD YAAALRAAGV RKGDRVMVYM
PNSIEAVAVI LAAARIGAIS TTVFAGFSPK AVADRIELTE PKIIFTQDYS LRRGRRVPLK
ENIDEALKIS PWRPEKVVVK RALPEAEVAM EKGRDLTLDE FLELGKYTDC SPVFLEANEP
LFIMPTSGTT AKPKPVVHVH GGYQVWIWHG AKLVYGLEPG DVVFNTSDIG WIVGQSYIVF
APLIIGATSI LFDGAIDYPR PDVFWEVVEK YRPTLIWTSP TAARLLMRLG VEQARKHDLS
SVRRVVTAGE VLNPEVWRWL YEDVFQRRVP VIDHMWQTET GGPIFGYPYA LVKDMGYGME
YVKIKPGSAG QPLPGVEFEI VDEKGNPLPP MHKGIVVIKR PFPGLTPTLW KDHERYLKDY
WQRFEGRLVY YTGDAAHVDE EGYIWFGGRA DEVIKIAGHR IGTIEVESAL LTHPAVAEAA
VVGVPDPLRG EAIAAFVVLK PGWRPTEELK RELIEHVRRT FGPIAVFAGV EFVNMLPKTR
SGKIMRRVLK RVWTGEPIGD ISTIEEEASV EEVKEAVSRM KILAETSRE
//
