ID A4YNG9_BRASO Unreviewed; 495 AA.
AC A4YNG9;
DT 29-MAY-2007, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2007, sequence version 1.
DT 27-MAR-2024, entry version 87.
DE SubName: Full=Aldehyde dehydrogenase NAD-linked {ECO:0000313|EMBL:CAL75445.1};
DE EC=1.2.1.3 {ECO:0000313|EMBL:CAL75445.1};
GN OrderedLocusNames=BRADO1563 {ECO:0000313|EMBL:CAL75445.1};
OS Bradyrhizobium sp. (strain ORS 278).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Nitrobacteraceae; Bradyrhizobium.
OX NCBI_TaxID=114615 {ECO:0000313|EMBL:CAL75445.1, ECO:0000313|Proteomes:UP000001994};
RN [1] {ECO:0000313|EMBL:CAL75445.1, ECO:0000313|Proteomes:UP000001994}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ORS 278 {ECO:0000313|Proteomes:UP000001994};
RX PubMed=17540897; DOI=10.1126/science.1139548;
RA Giraud E., Moulin L., Vallenet D., Barbe V., Cytryn E., Avarre J.C.,
RA Jaubert M., Simon D., Cartieaux F., Prin Y., Bena G., Hannibal L.,
RA Fardoux J., Kojadinovic M., Vuillet L., Lajus A., Cruveiller S., Rouy Z.,
RA Mangenot S., Segurens B., Dossat C., Franck W.L., Chang W.S., Saunders E.,
RA Bruce D., Richardson P., Normand P., Dreyfus B., Pignol D., Stacey G.,
RA Emerich D., Vermeglio A., Medigue C., Sadowsky M.;
RT "Legumes symbioses: absence of nod genes in photosynthetic bradyrhizobia.";
RL Science 316:1307-1312(2007).
CC -!- SIMILARITY: Belongs to the aldehyde dehydrogenase family.
CC {ECO:0000256|RuleBase:RU003345}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CU234118; CAL75445.1; -; Genomic_DNA.
DR AlphaFoldDB; A4YNG9; -.
DR STRING; 114615.BRADO1563; -.
DR KEGG; bra:BRADO1563; -.
DR eggNOG; COG1012; Bacteria.
DR HOGENOM; CLU_005391_1_0_5; -.
DR Proteomes; UP000001994; Chromosome.
DR GO; GO:0004029; F:aldehyde dehydrogenase (NAD+) activity; IEA:UniProtKB-EC.
DR GO; GO:0043878; F:glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity; IEA:UniProtKB-EC.
DR CDD; cd07097; ALDH_KGSADH-YcbD; 1.
DR InterPro; IPR016161; Ald_DH/histidinol_DH.
DR InterPro; IPR016163; Ald_DH_C.
DR InterPro; IPR016160; Ald_DH_CS_CYS.
DR InterPro; IPR029510; Ald_DH_CS_GLU.
DR InterPro; IPR016162; Ald_DH_N.
DR InterPro; IPR015590; Aldehyde_DH_dom.
DR PANTHER; PTHR11699:SF211; ALDEHYDE DEHYDROGENASE FAMILY 16 MEMBER A1; 1.
DR PANTHER; PTHR11699; ALDEHYDE DEHYDROGENASE-RELATED; 1.
DR Pfam; PF00171; Aldedh; 1.
DR SUPFAM; SSF53720; ALDH-like; 1.
DR PROSITE; PS00070; ALDEHYDE_DEHYDR_CYS; 1.
DR PROSITE; PS00687; ALDEHYDE_DEHYDR_GLU; 1.
PE 3: Inferred from homology;
KW NADP {ECO:0000256|ARBA:ARBA00022857};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000256|RuleBase:RU003345};
KW Reference proteome {ECO:0000313|Proteomes:UP000001994}.
FT DOMAIN 26..489
FT /note="Aldehyde dehydrogenase"
FT /evidence="ECO:0000259|Pfam:PF00171"
FT ACT_SITE 263
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10007"
SQ SEQUENCE 495 AA; 52940 MW; A1A2EB3CCC92B403 CRC64;
MCQHSRASLE SFEMNAILKN FIAGEWVDGS GVTRNINPSN TNDVVGEYAK ADKAQTEKAI
AAAKAAFPAW SRSTPQERYD ALNKISAEIL SRKEELGRLL AREEGKTLPE GIGEVARAGQ
IFAFFAGEAL RLTGEKGASV RPGLDVEITR EAVGVVGMIT PWNFPIAIPA WKIAPALCYG
NTVVFKPAEL VPGSAHALSE IIARSGIPAG VFNLVVGSGS VVGQTLLEHP DVAAISFTGS
VGTGRKIAQA CVLSNPMKKF QLEMGGKNPL VVLDDADVKV AVEAAANGAY FSTGQRCTAS
SRLIVTEGIH DKFVAALTER LKGLVVDDAV KQGTHIGPVV DGNQLEQDQR YLKIGQDEGA
KLAWGGELLN RESPGFYMQP ALFTEANNNM RIAREEIFGP VACVIRAKNY DEALAISNDT
EFGLAAGVCT TSLKYASHFK RNSEAGMVMV NLPTAGVDYH VPFGGRKGSS YGAREQGSYA
REFYTTVKTA YTFPV
//
