ID   A5EQF4_BRASB            Unreviewed;       482 AA.
AC   A5EQF4;
DT   12-JUN-2007, integrated into UniProtKB/TrEMBL.
DT   12-JUN-2007, sequence version 1.
DT   27-MAR-2024, entry version 88.
DE   SubName: Full=Aldehyde dehydrogenase {ECO:0000313|EMBL:ABQ38398.1};
DE            EC=1.2.1.3 {ECO:0000313|EMBL:ABQ38398.1};
GN   OrderedLocusNames=BBta_6489 {ECO:0000313|EMBL:ABQ38398.1};
OS   Bradyrhizobium sp. (strain BTAi1 / ATCC BAA-1182).
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC   Nitrobacteraceae; Bradyrhizobium.
OX   NCBI_TaxID=288000 {ECO:0000313|EMBL:ABQ38398.1, ECO:0000313|Proteomes:UP000000246};
RN   [1] {ECO:0000313|EMBL:ABQ38398.1, ECO:0000313|Proteomes:UP000000246}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BTAi1 / ATCC BAA-1182 {ECO:0000313|Proteomes:UP000000246};
RX   PubMed=17540897; DOI=10.1126/science.1139548;
RA   Giraud E., Moulin L., Vallenet D., Barbe V., Cytryn E., Avarre J.C.,
RA   Jaubert M., Simon D., Cartieaux F., Prin Y., Bena G., Hannibal L.,
RA   Fardoux J., Kojadinovic M., Vuillet L., Lajus A., Cruveiller S., Rouy Z.,
RA   Mangenot S., Segurens B., Dossat C., Franck W.L., Chang W.S., Saunders E.,
RA   Bruce D., Richardson P., Normand P., Dreyfus B., Pignol D., Stacey G.,
RA   Emerich D., Vermeglio A., Medigue C., Sadowsky M.;
RT   "Legumes symbioses: absence of nod genes in photosynthetic bradyrhizobia.";
RL   Science 316:1307-1312(2007).
CC   -!- SIMILARITY: Belongs to the aldehyde dehydrogenase family.
CC       {ECO:0000256|RuleBase:RU003345}.
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DR   EMBL; CP000494; ABQ38398.1; -; Genomic_DNA.
DR   RefSeq; WP_012046339.1; NC_009485.1.
DR   AlphaFoldDB; A5EQF4; -.
DR   STRING; 288000.BBta_6489; -.
DR   KEGG; bbt:BBta_6489; -.
DR   eggNOG; COG1012; Bacteria.
DR   HOGENOM; CLU_005391_1_0_5; -.
DR   OrthoDB; 9812625at2; -.
DR   Proteomes; UP000000246; Chromosome.
DR   GO; GO:0004029; F:aldehyde dehydrogenase (NAD+) activity; IEA:UniProtKB-EC.
DR   GO; GO:0043878; F:glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity; IEA:UniProtKB-EC.
DR   CDD; cd07097; ALDH_KGSADH-YcbD; 1.
DR   InterPro; IPR016161; Ald_DH/histidinol_DH.
DR   InterPro; IPR016163; Ald_DH_C.
DR   InterPro; IPR016160; Ald_DH_CS_CYS.
DR   InterPro; IPR029510; Ald_DH_CS_GLU.
DR   InterPro; IPR016162; Ald_DH_N.
DR   InterPro; IPR015590; Aldehyde_DH_dom.
DR   PANTHER; PTHR11699:SF211; ALDEHYDE DEHYDROGENASE FAMILY 16 MEMBER A1; 1.
DR   PANTHER; PTHR11699; ALDEHYDE DEHYDROGENASE-RELATED; 1.
DR   Pfam; PF00171; Aldedh; 1.
DR   SUPFAM; SSF53720; ALDH-like; 1.
DR   PROSITE; PS00070; ALDEHYDE_DEHYDR_CYS; 1.
DR   PROSITE; PS00687; ALDEHYDE_DEHYDR_GLU; 1.
PE   3: Inferred from homology;
KW   NADP {ECO:0000256|ARBA:ARBA00022857};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW   ECO:0000256|RuleBase:RU003345}.
FT   DOMAIN          13..476
FT                   /note="Aldehyde dehydrogenase"
FT                   /evidence="ECO:0000259|Pfam:PF00171"
FT   ACT_SITE        250
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU10007"
SQ   SEQUENCE   482 AA;  51450 MW;  EC88819291D39535 CRC64;
     MNAILKNFIA GEWVDGSGVT RNINPSNTND VVGEYAKADR AQTEKAIAAA KAAFPAWSRS
     TPQERYDALN KISAEILSRK EELGRLLARE EGKTLPEGIG EVARAGQIFA FFAGEALRLT
     GEKGASVRPG LDVEITREAV GVVGMITPWN FPIAIPAWKI APALCYGNTV VFKPAELVPG
     SAHALSEIIA RSGLPAGVFN LVVGSGSVVG QTLLEHPDVA AISFTGSVGT GRKIAQACVL
     SNPMKKFQLE MGGKNPLVVL DDADVKVAVE AAANGAYFST GQRCTASSRL IVTEGIHDTF
     VAALTERLKG LVVDDAVKQG THIGPVVDAN QLEQDQRYLK IGQDEGAKLA WGGELLNRET
     PGFYMQPALF TEATNNMRIA REEIFGPVAC VIRAKNYDEA LAISNDTEFG LAAGVCTTSL
     KYASHFKRNS EAGMVMVNLP TAGVDYHVPF GGRKGSSYGA REQGSYAREF YTTVKTAYTF
     PV
//