ID A7GAI0_CLOBL Unreviewed; 332 AA.
AC A7GAI0;
DT 11-SEP-2007, integrated into UniProtKB/TrEMBL.
DT 11-SEP-2007, sequence version 1.
DT 27-MAR-2024, entry version 78.
DE SubName: Full=Dehydrogenase, isocitrate/isopropylmalate family {ECO:0000313|EMBL:ABS42164.1};
GN OrderedLocusNames=CLI_0504 {ECO:0000313|EMBL:ABS42164.1};
OS Clostridium botulinum (strain Langeland / NCTC 10281 / Type F).
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=441772 {ECO:0000313|EMBL:ABS42164.1, ECO:0000313|Proteomes:UP000002410};
RN [1] {ECO:0000313|Proteomes:UP000002410}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Langeland / NCTC 10281 / Type F
RC {ECO:0000313|Proteomes:UP000002410};
RA Brinkac L.M., Daugherty S., Dodson R.J., Madupu R., Brown J.L., Bruce D.,
RA Detter C., Munk C., Smith L.A., Smith T.J., White O., Brettin T.S.;
RL Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the isocitrate and isopropylmalate
CC dehydrogenases family. {ECO:0000256|ARBA:ARBA00007769}.
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DR EMBL; CP000728; ABS42164.1; -; Genomic_DNA.
DR RefSeq; WP_003399589.1; NC_009699.1.
DR AlphaFoldDB; A7GAI0; -.
DR KEGG; cbf:CLI_0504; -.
DR HOGENOM; CLU_031953_0_1_9; -.
DR Proteomes; UP000002410; Chromosome.
DR GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR Gene3D; 3.40.718.10; Isopropylmalate Dehydrogenase; 1.
DR InterPro; IPR019818; IsoCit/isopropylmalate_DH_CS.
DR InterPro; IPR024084; IsoPropMal-DH-like_dom.
DR PANTHER; PTHR11835; DECARBOXYLATING DEHYDROGENASES-ISOCITRATE, ISOPROPYLMALATE, TARTRATE; 1.
DR PANTHER; PTHR11835:SF34; ISOCITRATE DEHYDROGENASE [NAD] SUBUNIT ALPHA, MITOCHONDRIAL; 1.
DR Pfam; PF00180; Iso_dh; 1.
DR SMART; SM01329; Iso_dh; 1.
DR SUPFAM; SSF53659; Isocitrate/Isopropylmalate dehydrogenase-like; 1.
DR PROSITE; PS00470; IDH_IMDH; 1.
PE 3: Inferred from homology;
FT DOMAIN 4..328
FT /note="Isopropylmalate dehydrogenase-like"
FT /evidence="ECO:0000259|SMART:SM01329"
SQ SEQUENCE 332 AA; 35998 MW; 25CA488736B78641 CRC64;
MKHNITLIPG DGIGPEVTEA ARKVIDAVGV DINWHVVEAG EKVLDQYGTP LPDYVLDSIK
ETKVALKGPV TTPVGKGFRS VNVTLRKSLN LYANIRPVKS YKGIKSRYEN VDLIIVRENT
EDLYAGIEHM IGDDIAESIK VITKKASDRI VDYAFDMARK ENRNKVTAVH KANIMKLSDG
LFLNCAKEVA SKNKDIDFED VIVDAMAMKL VLNPEKYDVL VMPNLYGDIL SDMAAGLVGG
LGLLPGANIG YEGAVFEAAH GAAPDIAGKN KANPTACILS GAMMLNYIGE NEKAKKIENA
IEKVFVEGKC LTEDLGGSST TEEFTKAIIE NL
//
