ID A7ZE58_CAMC1 Unreviewed; 610 AA.
AC A7ZE58;
DT 23-OCT-2007, integrated into UniProtKB/TrEMBL.
DT 23-OCT-2007, sequence version 1.
DT 27-MAR-2024, entry version 80.
DE SubName: Full=Cell division protein FtsI / penicillin-binding protein {ECO:0000313|EMBL:EAT97765.2};
DE EC=3.4.16.4 {ECO:0000313|EMBL:EAT97765.2};
GN Name=ftsI {ECO:0000313|EMBL:EAT97765.2};
GN ORFNames=CCC13826_0055 {ECO:0000313|EMBL:EAT97765.2};
OS Campylobacter concisus (strain 13826).
OC Bacteria; Campylobacterota; Epsilonproteobacteria; Campylobacterales;
OC Campylobacteraceae; Campylobacter.
OX NCBI_TaxID=360104 {ECO:0000313|EMBL:EAT97765.2, ECO:0000313|Proteomes:UP000001121};
RN [1] {ECO:0000313|Proteomes:UP000001121}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=13826 {ECO:0000313|Proteomes:UP000001121};
RA Fouts D.E., Mongodin E.F., Puiu D., Sebastian Y., Miller W.G.,
RA Mandrell R.E., On S., Nelson K.E.;
RT "Genome sequence of Campylobacter concisus 13826 isolated from human
RT feces.";
RL Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP000792; EAT97765.2; -; Genomic_DNA.
DR RefSeq; WP_012139982.1; NC_009802.2.
DR AlphaFoldDB; A7ZE58; -.
DR STRING; 360104.CCC13826_0055; -.
DR KEGG; cco:CCC13826_0055; -.
DR eggNOG; COG0768; Bacteria.
DR HOGENOM; CLU_009289_6_4_7; -.
DR OrthoDB; 9789078at2; -.
DR Proteomes; UP000001121; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR GO; GO:0009002; F:serine-type D-Ala-D-Ala carboxypeptidase activity; IEA:UniProtKB-EC.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR Gene3D; 3.30.450.330; -; 1.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR005311; PBP_dimer.
DR InterPro; IPR036138; PBP_dimer_sf.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR PANTHER; PTHR30627:SF1; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE FTSI; 1.
DR Pfam; PF03717; PBP_dimer; 1.
DR Pfam; PF00905; Transpeptidase; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
PE 4: Predicted;
KW Carboxypeptidase {ECO:0000313|EMBL:EAT97765.2};
KW Cell cycle {ECO:0000313|EMBL:EAT97765.2};
KW Cell division {ECO:0000313|EMBL:EAT97765.2};
KW Hydrolase {ECO:0000313|EMBL:EAT97765.2};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Protease {ECO:0000313|EMBL:EAT97765.2};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 9..28
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 46..210
FT /note="Penicillin-binding protein dimerisation"
FT /evidence="ECO:0000259|Pfam:PF03717"
FT DOMAIN 267..571
FT /note="Penicillin-binding protein transpeptidase"
FT /evidence="ECO:0000259|Pfam:PF00905"
SQ SEQUENCE 610 AA; 68140 MW; 5ACB4AF15A508F92 CRC64;
MNSRKSKITI LFLLITFGIS IFVLVIFYRA SIERKLPKLQ TSDVNTAIRG NIVTKDGFSI
SSSQKLYKVM LDTRNIDPNK KEMFIKLYSL YSGDDPNKVR KIINGTKGLV TLSYSIDAKG
ATYLQELSRK LNRKGILISY LDPKTGLASF QGMRVMESGQ NRKFMSKDAL TPAIGYVSKT
ESDALTKSKG VKGLERYYED YLAPIQNAKI LGPRDIGNNI ILTSDSNLAT RVDGYNAVLS
IPLKFQTKLE QILDEKREFL DAKELIICIM NSKNGEILAL ASSSRYDPSN IRKQDYSALN
SSASEYAYEV GSVFKPFIFS ILLQEKKVNP FELVNTYNGR YQLGKRIIKD THPEPFMSAE
DIIVHSSNIG MIQLVDRLNG PQIYQGLLNF GFSRKTGIDL PYEQVGMMPT VTKLNSSTYK
ATVSYGYGLQ ATFMQLLKAY NTFNNKGIEV TPHMVAYLER NGKRYDLPKA EPAQVISQET
AKIMKRILIK TVEKGTGLKA FTPGLEIGGK TGTAHIASGK GGYSNTYNGS FFGFVNDTRG
NSYTIGVLAR DPKKPYYYFG AQSALPTFKK AVDLMVEDGY LFPDPNVIAE FEAKKDKLKN
DKAKQKPALD
//
