ID A9NHU4_ACHLI Unreviewed; 450 AA.
AC A9NHU4;
DT 05-FEB-2008, integrated into UniProtKB/TrEMBL.
DT 05-FEB-2008, sequence version 1.
DT 27-MAR-2024, entry version 88.
DE RecName: Full=Aldehyde dehydrogenase {ECO:0000256|PIRNR:PIRNR036492};
GN OrderedLocusNames=ACL_1329 {ECO:0000313|EMBL:ABX81924.1};
OS Acholeplasma laidlawii (strain PG-8A).
OC Bacteria; Mycoplasmatota; Mollicutes; Acholeplasmatales;
OC Acholeplasmataceae; Acholeplasma.
OX NCBI_TaxID=441768 {ECO:0000313|EMBL:ABX81924.1, ECO:0000313|Proteomes:UP000008558};
RN [1] {ECO:0000313|EMBL:ABX81924.1, ECO:0000313|Proteomes:UP000008558}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PG-8A {ECO:0000313|EMBL:ABX81924.1,
RC ECO:0000313|Proteomes:UP000008558};
RX PubMed=21784942; DOI=10.1128/JB.05059-11;
RA Lazarev V.N., Levitskii S.A., Basovskii Y.I., Chukin M.M., Akopian T.A.,
RA Vereshchagin V.V., Kostrjukova E.S., Kovaleva G.Y., Kazanov M.D.,
RA Malko D.B., Vitreschak A.G., Sernova N.V., Gelfand M.S., Demina I.A.,
RA Serebryakova M.V., Galyamina M.A., Vtyurin N.N., Rogov S.I., Alexeev D.G.,
RA Ladygina V.G., Govorun V.M.;
RT "Complete genome and proteome of Acholeplasma laidlawii.";
RL J. Bacteriol. 193:4943-4953(2011).
CC -!- SIMILARITY: Belongs to the aldehyde dehydrogenase family.
CC {ECO:0000256|ARBA:ARBA00009986, ECO:0000256|PIRNR:PIRNR036492,
CC ECO:0000256|RuleBase:RU003345}.
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DR EMBL; CP000896; ABX81924.1; -; Genomic_DNA.
DR RefSeq; WP_012243255.1; NC_010163.1.
DR AlphaFoldDB; A9NHU4; -.
DR STRING; 441768.ACL_1329; -.
DR GeneID; 66294295; -.
DR KEGG; acl:ACL_1329; -.
DR eggNOG; COG1012; Bacteria.
DR HOGENOM; CLU_005391_3_1_14; -.
DR OrthoDB; 9762913at2; -.
DR Proteomes; UP000008558; Chromosome.
DR GO; GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR GO; GO:0006081; P:cellular aldehyde metabolic process; IEA:InterPro.
DR CDD; cd07136; ALDH_YwdH-P39616; 1.
DR InterPro; IPR016161; Ald_DH/histidinol_DH.
DR InterPro; IPR016163; Ald_DH_C.
DR InterPro; IPR016160; Ald_DH_CS_CYS.
DR InterPro; IPR029510; Ald_DH_CS_GLU.
DR InterPro; IPR016162; Ald_DH_N.
DR InterPro; IPR015590; Aldehyde_DH_dom.
DR InterPro; IPR012394; Aldehyde_DH_NAD(P).
DR PANTHER; PTHR43570; ALDEHYDE DEHYDROGENASE; 1.
DR PANTHER; PTHR43570:SF16; ALDEHYDE DEHYDROGENASE TYPE III, ISOFORM Q; 1.
DR Pfam; PF00171; Aldedh; 1.
DR PIRSF; PIRSF036492; ALDH; 1.
DR SUPFAM; SSF53720; ALDH-like; 1.
DR PROSITE; PS00070; ALDEHYDE_DEHYDR_CYS; 1.
DR PROSITE; PS00687; ALDEHYDE_DEHYDR_GLU; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000256|PIRNR:PIRNR036492};
KW Reference proteome {ECO:0000313|Proteomes:UP000008558}.
FT DOMAIN 11..419
FT /note="Aldehyde dehydrogenase"
FT /evidence="ECO:0000259|Pfam:PF00171"
FT ACT_SITE 207
FT /evidence="ECO:0000256|PIRSR:PIRSR036492-1,
FT ECO:0000256|PROSITE-ProRule:PRU10007"
FT ACT_SITE 241
FT /evidence="ECO:0000256|PIRSR:PIRSR036492-1"
SQ SEQUENCE 450 AA; 51554 MW; 138B3FC5580B9015 CRC64;
METIVQSQKT LFLSGKTLSY EFRIRQLQKL KQLIINYQDE ILEALFKDLH KSRFEAYSTE
VGYVLKSLTH TIKGLKKWMK PKKVKTPYYL SATSSYITYD ALGTILIIGP YNYPFQLIIE
PLIGAIAAGN TVMIKPSEFA TYTEKILVKL VNNHFDKDYL YVIEGDYTVT SKLLDSKFDH
IFFTGSSRVG QIVYEKASKH LTPVTLELGG KSPTIVDETA NLKIAAERIL FGKFLNAGQT
CIAPDYIYVH DTIHDEFINI LNQVINTRYS DMNYFGRIIN ERHYKRLIGL IDETKMIQKP
TVEAETKLIS PTVLIDVTWD DKVMQEEIFG PILPVLKYAN LKDLVSLLKT KDKPLALYLF
SNDKKNQTYV FENLTFGGGA INDTIMHVSN PYLPFGGIGM SGIGAYHGFY SFKLFSHTKG
YVKKATWFDL PIIYPPYTKF KEKLIRKIFK
//
