ID A9V5M6_MONBE Unreviewed; 2010 AA.
AC A9V5M6;
DT 05-FEB-2008, integrated into UniProtKB/TrEMBL.
DT 05-FEB-2008, sequence version 1.
DT 24-JAN-2024, entry version 53.
DE RecName: Full=Cilia- and flagella-associated protein 91 {ECO:0000256|ARBA:ARBA00029555};
GN ORFNames=MONBRDRAFT_33486 {ECO:0000313|EMBL:EDQ87067.1};
OS Monosiga brevicollis (Choanoflagellate).
OC Eukaryota; Choanoflagellata; Craspedida; Salpingoecidae; Monosiga.
OX NCBI_TaxID=81824 {ECO:0000313|EMBL:EDQ87067.1, ECO:0000313|Proteomes:UP000001357};
RN [1] {ECO:0000313|EMBL:EDQ87067.1, ECO:0000313|Proteomes:UP000001357}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MX1 / ATCC 50154 {ECO:0000313|Proteomes:UP000001357};
RX PubMed=18273011; DOI=10.1038/nature06617;
RG JGI Sequencing;
RA King N., Westbrook M.J., Young S.L., Kuo A., Abedin M., Chapman J.,
RA Fairclough S., Hellsten U., Isogai Y., Letunic I., Marr M., Pincus D.,
RA Putnam N., Rokas A., Wright K.J., Zuzow R., Dirks W., Good M.,
RA Goodstein D., Lemons D., Li W., Lyons J.B., Morris A., Nichols S.,
RA Richter D.J., Salamov A., Bork P., Lim W.A., Manning G., Miller W.T.,
RA McGinnis W., Shapiro H., Tjian R., Grigoriev I.V., Rokhsar D.;
RT "The genome of the choanoflagellate Monosiga brevicollis and the origin of
RT metazoans.";
RL Nature 451:783-788(2008).
CC -!- SIMILARITY: Belongs to the CFAP91 family.
CC {ECO:0000256|ARBA:ARBA00029468}.
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DR EMBL; CH991561; EDQ87067.1; -; Genomic_DNA.
DR RefSeq; XP_001748010.1; XM_001747958.1.
DR EnsemblProtists; EDQ87067; EDQ87067; MONBRDRAFT_33486.
DR GeneID; 5893268; -.
DR KEGG; mbr:MONBRDRAFT_33486; -.
DR eggNOG; KOG2657; Eukaryota.
DR InParanoid; A9V5M6; -.
DR Proteomes; UP000001357; Unassembled WGS sequence.
DR GO; GO:0042995; C:cell projection; IEA:UniProtKB-KW.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-KW.
DR Gene3D; 3.40.630.10; Zn peptidases; 1.
DR InterPro; IPR026720; CFAP91.
DR InterPro; IPR032840; CFAP91_dom.
DR InterPro; IPR041084; Ncstrn_small.
DR PANTHER; PTHR22455:SF10; CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 91; 1.
DR PANTHER; PTHR22455; UNCHARACTERIZED; 1.
DR Pfam; PF14738; CFAP91; 1.
DR Pfam; PF18266; Ncstrn_small; 1.
DR Pfam; PF05450; Nicastrin; 1.
DR SUPFAM; SSF53187; Zn-dependent exopeptidases; 1.
PE 3: Inferred from homology;
KW Cell projection {ECO:0000256|ARBA:ARBA00023273};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Reference proteome {ECO:0000313|Proteomes:UP000001357}.
FT DOMAIN 730..888
FT /note="Nicastrin small lobe"
FT /evidence="ECO:0000259|Pfam:PF18266"
FT DOMAIN 1435..1587
FT /note="CFAP91"
FT /evidence="ECO:0000259|Pfam:PF14738"
FT REGION 1344..1363
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1658..1687
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1959..2010
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 1515..1557
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1755..1845
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1663..1678
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1965..1997
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2010 AA; 220840 MW; BA223CE1F7745F50 CRC64;
MSANTSLDVG LHLDLCQEIW LRCRAAISAM DLFTALSACH TVHATVALAS LLSIWPHEAS
CRLGSLLVAL TQCRQPVDAL SPLWQAWAVH VSQAQWEQLL TTAEPLVPSG EVAMLILALS
RALFEAQRYD LCEVLCALIQ RPDWRTVLTD PAISLHPHLT RVFAPPVYAC STPQLKSVFV
AQPLPEPLWP QLSREHPQHV GMLTPPASLT ATPAAVDETN SLLPSCHAAS TLAGASIYLA
SPSMPSVEAL DLPLSPISRP VHVDIDVLCA HLDVEAAERP ALPAMAPNQP VVPPSPPSPL
PPAVLALDSD SAILAAFIDE PLLPDATLSD ARTQLLQNLP QLPVETPPLT AIGGELFSRG
QRQLNRAAPA DITARHWRQY LIEEPEINGT LGHTAAWQHR CRWLQNLGVT YRGGALRVLS
SLSWNPVLVL QTMHQSVVAP SSTLPADLMH DSACLLYLPS ARLPTVNHEP VLPTLLNVVP
SPILVSDESD QGVVTGEARL TNSQLQGGLE LHAGNSDLGG QEIWLPCRQG LSDALVFALE
TKQITCVMCA EEQFPLDVVV DEQVGIVLLP DLSPDGRTLS ARVLRAAALC TRIVVIVVNR
EWCVKVTCSD LIERELALAA RESPYTQDAW CKRDWLAECH ESPQWQWLMA SGCFNPMAAG
TLLLALTLRQ LLEAVAVKDF EGVLQSAPGV PLASLKMMRV LSLVAVLALW ATTLRDKVYT
KLSGNEGVNS CTRLINVTHE IGCTSPEDGA VGIFFKIESA DELDDFRSAT ESAYIVLLEQ
NMFAQSAVLR ELGRMDKVKG AFVYKGASLP MSGQTNWNPY GGGFAMDSLA DSGTIGSHWV
DFGSKAIYYL SDSDRDDVLA RYAALNVAGK GKKPNYPVWG ARLKNFMYGV RDTDLCLRRK
HCDPLSGQNV WGSTRLVESD SEVILATAQM DAFSFFHDLS YGANSDASAV VSLIGAARLL
GLEENYDVVA NLQRNIIFNL FNGESFGYIG SSRLGFDLSR APHWPSVDQS LSFENIKGYL
ELSQVLEGDS LHAHSYKSNA DTANIVAKLQ AAAAGSSTTV VDDTASELPP ASLRGFLNEW
RDTTKQDAFP GVVVTAYDST GFANKYHGSH LDDGIATSST SDETRARLCD TAVLTAKTLV
AMANNTDVAS VSLPVDSADS AFCDFLQEMF DCVARNQTCE LARKAIGQSG ATADMPLSRY
IGVTRSSTVL NRGVYFFFNM LSEALAKDKN VSLGVNATCA PNNKVNEFQT VDWTDGRCMN
TTAYVSYIMS PAFESYYKLK SEGSNLTIHR DPRWSTWTES VWGAISADMF LMEDPAVQRT
HRLPTGATTT MPSAENMFSE LQHHPRATQH AGPPPAADVP HNGPQIMERM AMAARDYNAA
EPQGRDLLRF LNSSFLPMPT SGGFNTALLK LDMQAGPGLS APIELPPGSM VTVATQTDYR
ESETQTDPYT PDYVVRPGSA PEVLTLATLA HGVGLPAGLA EVEMIERARA RRAWEATLPP
VEDASRAIER SRAIEARELE ELKFREEEIQ RVQDERLQVL EQLIVELESN KQQDREDKLN
RHYQQRQIER NRMLARSERQ AVKDIRKLTK ARQNIEGNLK RRDIVEQYSN PASEEFAPTR
TLGGGVHDQH ANRYRVDSKH VSSYQGLLDL EASLPKSVTT PRARAAKGTN TSATGRRGGM
ASASRRRMQD TLRQLDETMS MARTGTLPIL PPIRCVERIE KAKSILRGRA MQNEMYEQKE
QRRDLIEELR STHALQAAQQ AVKEKEREQL QARREADARE TRRQATITAA VNATQSAHLG
NTLDFLSKEL VRLQEEHRIH AFAVMAERER RMREAEEAGQ RQAEEHRRAQ GDEIFRQMMQ
VHNGTVDSYL ESILLAAQED VADEQAREFV REQARRIDAA AAEAHASGYD ETDLGAQAIA
SELVTSFLLP EVEREALRGS LQREQRKLLQ GAHEAVFAKT QEVEGQRRWT GSRAATASGS
RPRTASAQTQ SRPHTTPAIA EHTGLEEDNN
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