ID B1I307_DESAP Unreviewed; 813 AA.
AC B1I307;
DT 29-APR-2008, integrated into UniProtKB/TrEMBL.
DT 29-APR-2008, sequence version 1.
DT 27-MAR-2024, entry version 80.
DE RecName: Full=phosphomannomutase {ECO:0000256|ARBA:ARBA00012730};
DE EC=5.4.2.8 {ECO:0000256|ARBA:ARBA00012730};
GN OrderedLocusNames=Daud_0863 {ECO:0000313|EMBL:ACA59376.1};
OS Desulforudis audaxviator (strain MP104C).
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Peptococcaceae;
OC Desulforudis.
OX NCBI_TaxID=477974 {ECO:0000313|EMBL:ACA59376.1, ECO:0000313|Proteomes:UP000008544};
RN [1] {ECO:0000313|Proteomes:UP000008544}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MP104C {ECO:0000313|Proteomes:UP000008544};
RA Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E.,
RA Tice H., Bruce D., Pitluck S., Lowry S.R., Larimer F., Land M.L.,
RA Hauser L., Kyrpides N., Ivanova N.N., Richardson P.;
RT "Complete sequence of chromosome of Desulforudis audaxviator MP104C.";
RL Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ACA59376.1, ECO:0000313|Proteomes:UP000008544}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MP104C {ECO:0000313|EMBL:ACA59376.1,
RC ECO:0000313|Proteomes:UP000008544};
RX PubMed=18845759; DOI=10.1126/science.1155495;
RA Chivian D., Brodie E.L., Alm E.J., Culley D.E., Dehal P.S., Desantis T.Z.,
RA Gihring T.M., Lapidus A., Lin L.H., Lowry S.R., Moser D.P.,
RA Richardson P.M., Southam G., Wanger G., Pratt L.M., Andersen G.L.,
RA Hazen T.C., Brockman F.J., Arkin A.P., Onstott T.C.;
RT "Environmental genomics reveals a single-species ecosystem deep within
RT Earth.";
RL Science 322:275-278(2008).
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- SIMILARITY: Belongs to the phosphohexose mutase family.
CC {ECO:0000256|ARBA:ARBA00010231}.
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DR EMBL; CP000860; ACA59376.1; -; Genomic_DNA.
DR AlphaFoldDB; B1I307; -.
DR STRING; 477974.Daud_0863; -.
DR KEGG; dau:Daud_0863; -.
DR eggNOG; COG0836; Bacteria.
DR eggNOG; COG1109; Bacteria.
DR HOGENOM; CLU_014562_0_0_9; -.
DR OrthoDB; 9806956at2; -.
DR Proteomes; UP000008544; Chromosome.
DR GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR GO; GO:0008928; F:mannose-1-phosphate guanylyltransferase (GDP) activity; IEA:UniProtKB-EC.
DR GO; GO:0004475; F:mannose-1-phosphate guanylyltransferase (GTP) activity; IEA:InterPro.
DR GO; GO:0004615; F:phosphomannomutase activity; IEA:UniProtKB-EC.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR CDD; cd02509; GDP-M1P_Guanylyltransferase; 1.
DR CDD; cd03089; PMM_PGM; 1.
DR Gene3D; 3.40.120.10; Alpha-D-Glucose-1,6-Bisphosphate, subunit A, domain 3; 3.
DR Gene3D; 3.30.310.50; Alpha-D-phosphohexomutase, C-terminal domain; 1.
DR InterPro; IPR005844; A-D-PHexomutase_a/b/a-I.
DR InterPro; IPR016055; A-D-PHexomutase_a/b/a-I/II/III.
DR InterPro; IPR005845; A-D-PHexomutase_a/b/a-II.
DR InterPro; IPR005846; A-D-PHexomutase_a/b/a-III.
DR InterPro; IPR005843; A-D-PHexomutase_C.
DR InterPro; IPR036900; A-D-PHexomutase_C_sf.
DR InterPro; IPR016066; A-D-PHexomutase_CS.
DR InterPro; IPR005841; Alpha-D-phosphohexomutase_SF.
DR InterPro; IPR049577; GMPP_N.
DR InterPro; IPR005835; NTP_transferase_dom.
DR InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR PANTHER; PTHR43771; PHOSPHOMANNOMUTASE; 1.
DR PANTHER; PTHR43771:SF1; PHOSPHOMANNOMUTASE; 1.
DR Pfam; PF00483; NTP_transferase; 1.
DR Pfam; PF02878; PGM_PMM_I; 1.
DR Pfam; PF02879; PGM_PMM_II; 1.
DR Pfam; PF02880; PGM_PMM_III; 1.
DR Pfam; PF00408; PGM_PMM_IV; 1.
DR PRINTS; PR00509; PGMPMM.
DR SUPFAM; SSF159283; Guanosine diphospho-D-mannose pyrophosphorylase/mannose-6-phosphate isomerase linker domain; 1.
DR SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 1.
DR SUPFAM; SSF55957; Phosphoglucomutase, C-terminal domain; 1.
DR SUPFAM; SSF53738; Phosphoglucomutase, first 3 domains; 3.
DR PROSITE; PS00710; PGM_PMM; 1.
PE 3: Inferred from homology;
KW Isomerase {ECO:0000256|ARBA:ARBA00023235, ECO:0000313|EMBL:ACA59376.1};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotidyltransferase {ECO:0000313|EMBL:ACA59376.1};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000008544};
KW Transferase {ECO:0000313|EMBL:ACA59376.1}.
FT DOMAIN 12..292
FT /note="Nucleotidyl transferase"
FT /evidence="ECO:0000259|Pfam:PF00483"
FT DOMAIN 364..477
FT /note="Alpha-D-phosphohexomutase alpha/beta/alpha"
FT /evidence="ECO:0000259|Pfam:PF02878"
FT DOMAIN 514..613
FT /note="Alpha-D-phosphohexomutase alpha/beta/alpha"
FT /evidence="ECO:0000259|Pfam:PF02879"
FT DOMAIN 618..726
FT /note="Alpha-D-phosphohexomutase alpha/beta/alpha"
FT /evidence="ECO:0000259|Pfam:PF02880"
FT DOMAIN 733..805
FT /note="Alpha-D-phosphohexomutase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00408"
SQ SEQUENCE 813 AA; 90308 MW; E283D921F0CCFD6C CRC64;
MTASERRWFP VAVIMAGGVG TRFWPLSTED RPKQFLQLFG ERSLLQQTRD RLAAFVAPEH
TLVLTNERFT YLVRAQLPEI PEANIIGEPA RRDTAGAVTL AALLCRRRFG DPAMIVLPAD
HVIQPVEEFQ RVLASALEAA RREKALYAFG IPPTHPATGY GYLERGEKVL DDGGVVHYRL
LRFKEKPDAE TARAYVDSGR FFWNSGIFVW TADTILEAVR KHLPGHLGVL EPLAALDGSD
DWTTGLRRLF PLLPAVSIDY GVMEKAENVR AVAATFSWSD VGGWTALEPF LEKDTSNNAC
RGRVRSLKAG SNIVFCEDPE ETVSLIGVRD LIVVRAGKQT LVVPRQRAEE LKELAEPKKR
TVCFKAYDIR GRVPDDLNED IAYAVGQAYT ALFRPARVVV GRDVRHSSPP LSRALIRGLT
DSGVDVLDIG LCGTEQVYFA TFDLGVDGGI MVTASHNPVD YNGMKLVRKE ARPVSGDSGL
REMEALLAGG DLAARLPKRA RPPGRVTRVE IMDRYVAHLL RYVDVSILKP YKVVCNAGNG
GAGLVIDALE KHLPFRFSKY FFEPDGTFPN GVPNPLLPEN RRVTSEAVLR EGADIGIAWD
GDFDRCFLFD EKGAFVEGYY IVGLLAGHQL ALHPGAKIIH DPRLTWNTIE IVRQAGGIPV
LNKTGHAFIK ERMRAEDAVY GGEMSAHHYF RDFAYCDSGM IPWLLVLEIM SRTGKPLSEL
VGERMRLFPI SGEINRSVAD PAAVLARVRA RYEPEALNVD ETDGISLEFE RWRFNLRLSN
TEPVVRLNVE TRGDEALLRQ KTAEILAEMD GQG
//
