ID   B1ZKL3_METPB            Unreviewed;       576 AA.
AC   B1ZKL3;
DT   20-MAY-2008, integrated into UniProtKB/TrEMBL.
DT   20-MAY-2008, sequence version 1.
DT   27-MAR-2024, entry version 95.
DE   RecName: Full=DNA ligase (ATP) {ECO:0000256|ARBA:ARBA00012727};
DE            EC=6.5.1.1 {ECO:0000256|ARBA:ARBA00012727};
GN   OrderedLocusNames=Mpop_3432 {ECO:0000313|EMBL:ACB81583.1};
OS   Methylorubrum populi (strain ATCC BAA-705 / NCIMB 13946 / BJ001)
OS   (Methylobacterium populi).
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC   Methylobacteriaceae; Methylorubrum.
OX   NCBI_TaxID=441620 {ECO:0000313|EMBL:ACB81583.1, ECO:0000313|Proteomes:UP000007136};
RN   [1] {ECO:0000313|EMBL:ACB81583.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BJ001 {ECO:0000313|EMBL:ACB81583.1};
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA   Bruce D., Goodwin L., Pitluck S., Chertkov O., Brettin T., Detter J.C.,
RA   Han C., Kuske C.R., Schmutz J., Larimer F., Land M., Hauser L.,
RA   Kyrpides N., Mikhailova N., Marx C., Richardson P.;
RT   "Complete sequence of chromosome of Methylobacterium populi BJ001.";
RL   Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + (deoxyribonucleotide)n-3'-hydroxyl + 5'-phospho-
CC         (deoxyribonucleotide)m = (deoxyribonucleotide)n+m + AMP +
CC         diphosphate.; EC=6.5.1.1; Evidence={ECO:0000256|ARBA:ARBA00034003};
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DR   EMBL; CP001029; ACB81583.1; -; Genomic_DNA.
DR   RefSeq; WP_012455300.1; NC_010725.1.
DR   AlphaFoldDB; B1ZKL3; -.
DR   STRING; 441620.Mpop_3432; -.
DR   KEGG; mpo:Mpop_3432; -.
DR   eggNOG; COG1793; Bacteria.
DR   HOGENOM; CLU_005138_6_2_5; -.
DR   OrthoDB; 9767858at2; -.
DR   Proteomes; UP000007136; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003910; F:DNA ligase (ATP) activity; IEA:UniProtKB-EC.
DR   GO; GO:0006310; P:DNA recombination; IEA:InterPro.
DR   GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR   CDD; cd07897; Adenylation_DNA_ligase_Bac1; 1.
DR   CDD; cd07972; OBF_DNA_ligase_Arch_LigB; 1.
DR   Gene3D; 1.10.3260.10; DNA ligase, ATP-dependent, N-terminal domain; 1.
DR   Gene3D; 3.30.470.30; DNA ligase/mRNA capping enzyme; 1.
DR   Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR   InterPro; IPR026333; ATP_dep_DNA_lig_pp_1105_fam.
DR   InterPro; IPR012309; DNA_ligase_ATP-dep_C.
DR   InterPro; IPR012310; DNA_ligase_ATP-dep_cent.
DR   InterPro; IPR016059; DNA_ligase_ATP-dep_CS.
DR   InterPro; IPR036599; DNA_ligase_N_sf.
DR   InterPro; IPR012340; NA-bd_OB-fold.
DR   NCBIfam; TIGR04120; DNA_lig_bact; 1.
DR   PANTHER; PTHR45674; DNA LIGASE 1/3 FAMILY MEMBER; 1.
DR   PANTHER; PTHR45674:SF13; DNA LIGASE-RELATED; 1.
DR   Pfam; PF04679; DNA_ligase_A_C; 1.
DR   Pfam; PF01068; DNA_ligase_A_M; 1.
DR   SUPFAM; SSF56091; DNA ligase/mRNA capping enzyme, catalytic domain; 1.
DR   SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
DR   PROSITE; PS00697; DNA_LIGASE_A1; 1.
DR   PROSITE; PS50160; DNA_LIGASE_A3; 1.
PE   4: Predicted;
KW   DNA replication {ECO:0000256|ARBA:ARBA00022705};
KW   Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000313|EMBL:ACB81583.1}.
FT   DOMAIN          322..459
FT                   /note="ATP-dependent DNA ligase family profile"
FT                   /evidence="ECO:0000259|PROSITE:PS50160"
FT   REGION          87..116
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        90..113
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   576 AA;  64128 MW;  7EA391C59623F2E4 CRC64;
     MNDFAHLLDR LAYEPRRNAK LRLLQDFFAG TPDPERGWAL AAMTGGLTFR EAKPALIRAL
     VEERVDPVLF SLSHNYVGDL AETTALIWPG PEQDPPPSAR EGSPGPGHNN PPPSVPTLAE
     VVETLATTPK RALPQHLTRW LDALDETGRW ALLKLVTGNL RVGVSARLAK TAVGALGGHE
     ADAVEEVWHG LKPPYPELFA WVEGRGERPE SRNPAPFRPP MLSHPVEEFE DLDKLEPEAF
     SAEWKWDGIR VQLAGGRDNQ GRQVQKIYSR TGEDISDAFP DLAEAITFDG AIDGELLILR
     EGRVQSFNVL QQRLNRKAVT GKLLDEFPAH VRAYDVLSAE GEDLRGLPFA ERRPRLETLV
     RQLDHARIDL SPLVPFATWN EVAAARADPA SAGAGADADA IEGVMLKRLN SPYLPGRPKG
     PWWKWKREPY VVDAVMMYAQ RGHGKRSSFY SDYTFGCWRE GAEGEELVPV GKAYHGFTDA
     ELQKLDRYVR NHTTKRFGPV REVAYGRDAG LVLEIAFEGV QRSTRHKSGV AMRFPRVSRI
     RWDKPAAEAD RVEVLERILA RGEREVAPGA AMEASE
//