ID B4U287_STREM Unreviewed; 594 AA.
AC B4U287;
DT 23-SEP-2008, integrated into UniProtKB/TrEMBL.
DT 23-SEP-2008, sequence version 1.
DT 27-MAR-2024, entry version 73.
DE SubName: Full=Beta-galactosidase Bga {ECO:0000313|EMBL:ACG62104.1};
GN Name=bga {ECO:0000313|EMBL:ACG62104.1};
GN OrderedLocusNames=Sez_0741 {ECO:0000313|EMBL:ACG62104.1};
OS Streptococcus equi subsp. zooepidemicus (strain MGCS10565).
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC Streptococcus.
OX NCBI_TaxID=552526 {ECO:0000313|EMBL:ACG62104.1, ECO:0000313|Proteomes:UP000001873};
RN [1] {ECO:0000313|EMBL:ACG62104.1, ECO:0000313|Proteomes:UP000001873}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGCS10565 {ECO:0000313|EMBL:ACG62104.1,
RC ECO:0000313|Proteomes:UP000001873};
RX PubMed=18716664; DOI=10.1371/journal.pone.0003026;
RA Beres S.B., Sesso R., Pinto S.W.L., Hoe N.P., Porcella S.F., Deleo F.R.,
RA Musser J.M.;
RT "Genome sequence of a lancefield group C Streptococcus zooepidemicus strain
RT causing epidemic nephritis: new information about an old disease.";
RL PLoS ONE 3:E3026-E3026(2008).
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 35 family.
CC {ECO:0000256|ARBA:ARBA00009809, ECO:0000256|RuleBase:RU003679}.
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DR EMBL; CP001129; ACG62104.1; -; Genomic_DNA.
DR RefSeq; WP_012515378.1; NC_011134.1.
DR AlphaFoldDB; B4U287; -.
DR CAZy; GH35; Glycoside Hydrolase Family 35.
DR KEGG; sez:Sez_0741; -.
DR HOGENOM; CLU_007853_7_2_9; -.
DR Proteomes; UP000001873; Chromosome.
DR GO; GO:0004565; F:beta-galactosidase activity; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 2.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR InterPro; IPR026283; B-gal_1-like.
DR InterPro; IPR048912; BetaGal1-like_ABD1.
DR InterPro; IPR048913; BetaGal_gal-bd.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR031330; Gly_Hdrlase_35_cat.
DR InterPro; IPR001944; Glycoside_Hdrlase_35.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR23421:SF165; BETA-GALACTOSIDASE; 1.
DR PANTHER; PTHR23421; BETA-GALACTOSIDASE RELATED; 1.
DR Pfam; PF21317; BetaGal_ABD_1; 1.
DR Pfam; PF21467; BetaGal_gal-bd; 1.
DR Pfam; PF01301; Glyco_hydro_35; 1.
DR PIRSF; PIRSF006336; B-gal; 1.
DR PRINTS; PR00742; GLHYDRLASE35.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801}.
FT DOMAIN 9..327
FT /note="Glycoside hydrolase 35 catalytic"
FT /evidence="ECO:0000259|Pfam:PF01301"
FT DOMAIN 373..486
FT /note="Beta-galactosidase 1-like first all-beta"
FT /evidence="ECO:0000259|Pfam:PF21317"
FT DOMAIN 505..563
FT /note="Beta-galactosidase galactose-binding"
FT /evidence="ECO:0000259|Pfam:PF21467"
FT ACT_SITE 156
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR006336-1"
FT ACT_SITE 238
FT /note="Nucleophile"
FT /evidence="ECO:0000256|PIRSR:PIRSR006336-1"
SQ SEQUENCE 594 AA; 68329 MW; 013957F54E26EA26 CRC64;
MKQFCVKEQF YLDGKPFKIL SGAIHYFRIA PDSWPRVLYQ LKALGFNTVE TYIPWNMHEP
RKGQFTFEGI ADVEAFLDLA QEYGLYAIVR PSPYICAEWE FGGLPAWLLT ENCRVRSSDE
VFLKHVSDYY DVLLPKLVKR QLDNGGNILM FQLENEYGSY GEEKDYLRKL KELMLAKGIS
APLFTSDGPW LATLASGSLI DDDVFVTGNF GSNASKQFAS MQDFFQAHQK QWPLMCMEFW
LGWFNRWNEP IIRRDPKEAV DAIMEAIELG SINLYMFCGG TNFGFMNGSS ARLQKDLPQI
TSYDYDALLD EAGNPTKKYI LLQERLKERY PQLSFAEPMT SPTMALESIK LSARVSLFKT
IKNVSALKKS FYPCNMEELD QPTGYLLYRT HLARHSKEER LRVIDARDRI QLFLDEKHVK
TQYQEEIGQD ILIHQEDETT QLDLLVENMG RVSYGHKLTA PSQQKGLGRG LMADLHFVGH
WEHFLLDFQE LDWIDFSAGW TDGVPGFYAY DFDCQQPADT YLDLSQFGKG IALVNGVNLG
RFWKVGPTLS LYIPKGLLKQ GQNRLLIFET EGQFSESIRL TKEPIYNDIK GENL
//
